ko pathway ratio_in_study ratio_in_pop p_value ko04744 Phototransduction 14/233 36/7206 1.86919688828e-12 ko04724 Glutamatergic synapse 18/233 152/7206 1.67946889995e-06 ko04070 Phosphatidylinositol signaling system 14/233 112/7206 1.32555535058e-05 ko04725 Cholinergic synapse 15/233 160/7206 0.000194031028879 ko05032 Morphine addiction 12/233 110/7206 0.000209394488484 ko04740 Olfactory transduction 10/233 80/7206 0.000232498798177 ko04964 Proximal tubule bicarbonate reclamation 6/233 29/7206 0.000272411036615 ko04742 Taste transduction 8/233 61/7206 0.000709944266667 ko04727 GABAergic synapse 11/233 110/7206 0.00080966892075 ko04745 Phototransduction - fly 6/233 38/7206 0.00124143344027 ko04911 Insulin secretion 11/233 117/7206 0.0013515386493 ko04080 Neuroactive ligand-receptor interaction 26/233 423/7206 0.00152427299155 ko00562 Inositol phosphate metabolism 9/233 89/7206 0.00221528855566 ko04972 Pancreatic secretion 10/233 111/7206 0.00304024730159 ko04971 Gastric acid secretion 9/233 98/7206 0.00426874167027 ko04726 Serotonergic synapse 11/233 137/7206 0.0046892098574 ko04024 cAMP signaling pathway 18/233 279/7206 0.00485113966357 ko04919 Thyroid hormone signaling pathway 11/233 143/7206 0.00646010678492 ko04925 Aldosterone synthesis and secretion 9/233 105/7206 0.0067113759925 ko04020 Calcium signaling pathway 17/233 265/7206 0.00673340327446 ko04010 MAPK signaling pathway 19/233 321/7206 0.00926719770473 ko04960 Aldosterone-regulated sodium reabsorption 5/233 41/7206 0.00981901344 ko00830 Retinol metabolism 5/233 42/7206 0.010859669612 ko04961 Endocrine and other factor-regulated calcium reabsorption 6/233 59/7206 0.0115473494938 ko04713 Circadian entrainment 10/233 136/7206 0.0124666992737 ko04810 Regulation of actin cytoskeleton 2/233 264/7206 0.0126028801909 ko04072 Phospholipase D signaling pathway 13/233 197/7206 0.01267805838 ko04723 Retrograde endocannabinoid signaling 12/233 175/7206 0.0139852630367 ko04062 Chemokine signaling pathway 13/233 201/7206 0.0144076502281 ko04720 Long-term potentiation 8/233 99/7206 0.0144888755565 ko04728 Dopaminergic synapse 12/233 185/7206 0.0186720831756 ko04722 Neurotrophin signaling pathway 11/233 160/7206 0.0192967666061 ko04071 Sphingolipid signaling pathway 11/233 162/7206 0.0202572454783 ko00910 Nitrogen metabolism 3/233 19/7206 0.0220521398277 ko05166 HTLV-I infection 3/233 292/7206 0.0263839075921 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/233 1/7206 0.0323341659729 ko04970 Salivary secretion 7/233 95/7206 0.0336676641602 ko05033 Nicotine addiction 5/233 56/7206 0.033960829321 ko04974 Protein digestion and absorption 7/233 96/7206 0.0353575813043 ko05203 Viral carcinogenesis 3/233 277/7206 0.0360682410853 ko02010 ABC transporters 4/233 39/7206 0.036167305108 ko04260 Cardiac muscle contraction 7/233 98/7206 0.0389040751185 ko04721 Synaptic vesicle cycle 6/233 80/7206 0.0442435980643 ko04976 Bile secretion 6/233 80/7206 0.0442435980643 ko04973 Carbohydrate digestion and absorption 4/233 42/7206 0.0456971358054 ko04921 Oxytocin signaling pathway 12/233 209/7206 0.0458060381458 ko05230 Central carbon metabolism in cancer 6/233 81/7206 0.046548633547