ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	169/943	423/7206	6.67215460315e-47
ko05033	Nicotine addiction	48/943	56/7206	7.00287147305e-35
ko04724	Glutamatergic synapse	79/943	152/7206	2.5718139825e-31
ko05032	Morphine addiction	58/943	110/7206	1.20989420939e-23
ko04727	GABAergic synapse	57/943	110/7206	9.33221005329e-23
ko04728	Dopaminergic synapse	75/943	185/7206	3.03788307644e-21
ko04713	Circadian entrainment	62/943	136/7206	6.89161952508e-21
ko04024	cAMP signaling pathway	95/943	279/7206	3.15943308963e-20
ko04725	Cholinergic synapse	65/943	160/7206	1.34567288037e-18
ko04721	Synaptic vesicle cycle	43/943	80/7206	3.03908083101e-18
ko04723	Retrograde endocannabinoid signaling	68/943	175/7206	3.59424293174e-18
ko04911	Insulin secretion	49/943	117/7206	6.27753889731e-15
ko04742	Taste transduction	32/943	61/7206	1.66338531336e-13
ko04921	Oxytocin signaling pathway	65/943	209/7206	4.557105873e-12
ko04020	Calcium signaling pathway	76/943	265/7206	6.63050214863e-12
ko04726	Serotonergic synapse	49/943	137/7206	7.67114287087e-12
ko05031	Amphetamine addiction	38/943	91/7206	8.14401327661e-12
ko04720	Long-term potentiation	39/943	99/7206	3.73017243514e-11
ko04261	Adrenergic signaling in cardiomyocytes	61/943	205/7206	2.72715224981e-10
ko04744	Phototransduction	20/943	36/7206	1.65304696911e-09
ko05030	Cocaine addiction	30/943	73/7206	2.09843033379e-09
ko04970	Salivary secretion	33/943	95/7206	4.80204810647e-08
ko03040	Spliceosome	1/943	145/7206	5.9344878118e-08
ko05203	Viral carcinogenesis	10/943	277/7206	8.40021651733e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	27/943	74/7206	2.55297024424e-07
ko04971	Gastric acid secretion	32/943	98/7206	3.90642282018e-07
ko04740	Olfactory transduction	28/943	80/7206	4.17811544399e-07
ko04060	Cytokine-cytokine receptor interaction	5/943	191/7206	5.98742356484e-07
ko04010	MAPK signaling pathway	74/943	321/7206	6.51334271723e-07
ko04925	Aldosterone synthesis and secretion	33/943	105/7206	1.05444854604e-06
ko05168	Herpes simplex infection	5/943	182/7206	1.84446524312e-06
ko04621	NOD-like receptor signaling pathway	4/943	157/7206	6.28099251916e-06
ko04514	Cell adhesion molecules (CAMs)	36/943	130/7206	8.39392153102e-06
ko04972	Pancreatic secretion	32/943	111/7206	1.08464766722e-05
ko03013	RNA transport	5/943	166/7206	1.15296084268e-05
ko05164	Influenza A	5/943	167/7206	1.18329578964e-05
ko04072	Phospholipase D signaling pathway	48/943	197/7206	1.3331943982e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	25/943	79/7206	1.35295375619e-05
ko04022	cGMP-PKG signaling pathway	51/943	216/7206	2.02522131233e-05
ko04360	Axon guidance	53/943	233/7206	4.14781411636e-05
ko04260	Cardiac muscle contraction	28/943	98/7206	5.08757095976e-05
ko05322	Systemic lupus erythematosus	5/943	151/7206	7.10578879125e-05
ko04540	Gap junction	32/943	128/7206	0.000272375555304
ko04120	Ubiquitin mediated proteolysis	5/943	138/7206	0.000287449174535
ko04730	Long-term depression	22/943	78/7206	0.000308386840762
ko03008	Ribosome biogenesis in eukaryotes	1/943	79/7206	0.000315177282587
ko05169	Epstein-Barr virus infection	11/943	206/7206	0.000327584326314
ko04141	Protein processing in endoplasmic reticulum	9/943	184/7206	0.000340393675956
ko04915	Estrogen signaling pathway	32/943	131/7206	0.000344346981425
ko04612	Antigen processing and presentation	1/943	77/7206	0.000482667118389
ko05414	Dilated cardiomyopathy	28/943	112/7206	0.000562937609956
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/943	14/7206	0.000955022499559
ko04966	Collecting duct acid secretion	10/943	26/7206	0.00102676590576
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/943	182/7206	0.00112828181438
ko04976	Bile secretion	21/943	80/7206	0.00128578353393
ko00240	Pyrimidine metabolism	4/943	110/7206	0.00145959625576
ko05162	Measles	5/943	120/7206	0.00154734585827
ko04110	Cell cycle	7/943	145/7206	0.00165482679935
ko05205	Proteoglycans in cancer	19/943	271/7206	0.00169661688762
ko04064	NF-kappa B signaling pathway	3/943	96/7206	0.00190017804806
ko04640	Hematopoietic cell lineage	1/943	64/7206	0.00235153788959
ko04745	Phototransduction - fly	12/943	38/7206	0.00243626080357
ko04750	Inflammatory mediator regulation of TRP channels	28/943	122/7206	0.00255374163998
ko04964	Proximal tubule bicarbonate reclamation	10/943	29/7206	0.00267913189104
ko04070	Phosphatidylinositol signaling system	26/943	112/7206	0.00276406784704
ko04350	TGF-beta signaling pathway	4/943	103/7206	0.00287645965343
ko05140	Leishmaniasis	2/943	75/7206	0.00313677846904
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/943	59/7206	0.00319848537361
ko04214	Apoptosis - fly	2/943	72/7206	0.00454951727403
ko00310	Lysine degradation	2/943	73/7206	0.00458208590356
ko04014	Ras signaling pathway	53/943	279/7206	0.00478337459556
ko03018	RNA degradation	3/943	84/7206	0.00524363712742
ko05016	Huntington's disease	15/943	215/7206	0.00535048576745
ko05161	Hepatitis B	11/943	173/7206	0.00588145900735
ko00480	Glutathione metabolism	1/943	55/7206	0.00776498912772
ko05321	Inflammatory bowel disease (IBD)	1/943	56/7206	0.0080493804166
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	6/943	15/7206	0.00865330966699
ko04924	Renin secretion	20/943	86/7206	0.0090759683142
ko04217	Necroptosis	12/943	178/7206	0.00924113851438
ko05145	Toxoplasmosis	7/943	126/7206	0.0105280485424
ko04015	Rap1 signaling pathway	51/943	278/7206	0.0108501333806
ko04146	Peroxisome	4/943	89/7206	0.0109460476276
ko00590	Arachidonic acid metabolism	1/943	52/7206	0.0115356304224
ko04140	Autophagy - animal	11/943	164/7206	0.0132828448923
ko04657	IL-17 signaling pathway	4/943	87/7206	0.0153359469672
ko05410	Hypertrophic cardiomyopathy (HCM)	22/943	100/7206	0.015606939694
ko05166	HTLV-I infection	25/943	292/7206	0.016746506197
ko01200	Carbon metabolism	8/943	128/7206	0.0169999809314
ko04973	Carbohydrate digestion and absorption	11/943	42/7206	0.0193098026001
ko00330	Arginine and proline metabolism	2/943	61/7206	0.0201165096479
ko05110	Vibrio cholerae infection	15/943	63/7206	0.0217881316073
ko04930	Type II diabetes mellitus	13/943	54/7206	0.0241296264016
ko05034	Alcoholism	43/943	238/7206	0.0243693441382
ko03022	Basal transcription factors	1/943	44/7206	0.0247415838812
ko00071	Fatty acid degradation	1/943	45/7206	0.0248030964193
ko00620	Pyruvate metabolism	1/943	46/7206	0.0253466483542
ko03420	Nucleotide excision repair	1/943	46/7206	0.0253466483542
ko04630	Jak-STAT signaling pathway	9/943	132/7206	0.0269035729995
ko03320	PPAR signaling pathway	3/943	69/7206	0.0295627404918
ko05215	Prostate cancer	7/943	111/7206	0.0323867621223
ko00983	Drug metabolism - other enzymes	1/943	42/7206	0.0365955415636
ko05222	Small cell lung cancer	5/943	89/7206	0.0380403556531
ko01524	Platinum drug resistance	4/943	76/7206	0.0396033118607
ko00280	Valine, leucine and isoleucine degradation	2/943	54/7206	0.0405602623805
ko04912	GnRH signaling pathway	24/943	122/7206	0.0407846489034
ko04510	Focal adhesion	21/943	240/7206	0.0409882025753
ko00512	Mucin type O-glycan biosynthesis	8/943	29/7206	0.0456708316612
ko04658	Th1 and Th2 cell differentiation	6/943	96/7206	0.0466392200065