ko pathway ratio_in_study ratio_in_pop p_value ko00281 Geraniol degradation 4/245 5/7206 6.34961697028e-06 ko04512 ECM-receptor interaction 12/245 79/7206 1.23339395704e-05 ko00020 Citrate cycle (TCA cycle) 8/245 35/7206 1.69033889601e-05 ko04510 Focal adhesion 21/245 240/7206 6.09359375768e-05 ko04060 Cytokine-cytokine receptor interaction 18/245 191/7206 8.00628714862e-05 ko05146 Amoebiasis 12/245 99/7206 0.000121837976595 ko04668 TNF signaling pathway 13/245 120/7206 0.000202656413429 ko04974 Protein digestion and absorption 11/245 96/7206 0.000383998037578 ko01200 Carbon metabolism 13/245 128/7206 0.000384831159658 ko05410 Hypertrophic cardiomyopathy (HCM) 11/245 100/7206 0.000547170824899 ko00620 Pyruvate metabolism 7/245 46/7206 0.000829976268446 ko04621 NOD-like receptor signaling pathway 14/245 157/7206 0.000870265030683 ko04657 IL-17 signaling pathway 9/245 87/7206 0.00266112021483 ko05164 Influenza A 13/245 167/7206 0.00439898566466 ko05414 Dilated cardiomyopathy 10/245 112/7206 0.00463799128607 ko04210 Apoptosis 14/245 180/7206 0.00501467264642 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 8/245 79/7206 0.00517285062641 ko04932 Non-alcoholic fatty liver disease (NAFLD) 14/245 182/7206 0.0052264426153 ko00760 Nicotinate and nicotinamide metabolism 5/245 34/7206 0.00541471405904 ko04380 Osteoclast differentiation 11/245 134/7206 0.00576955865773 ko00500 Starch and sucrose metabolism 5/245 35/7206 0.00614564616934 ko00643 Styrene degradation 2/245 4/7206 0.00660163109496 ko05161 Hepatitis B 13/245 173/7206 0.00825465037117 ko05145 Toxoplasmosis 10/245 126/7206 0.010455123882 ko04920 Adipocytokine signaling pathway 8/245 89/7206 0.0104855612803 ko05321 Inflammatory bowel disease (IBD) 6/245 56/7206 0.0113816374574 ko04623 Cytosolic DNA-sensing pathway 5/245 41/7206 0.0120333304267 ko00010 Glycolysis / Gluconeogenesis 7/245 74/7206 0.0124990359875 ko05142 Chagas disease (American trypanosomiasis) 10/245 130/7206 0.0128553565303 ko00362 Benzoate degradation 2/245 6/7206 0.0157752030818 ko00071 Fatty acid degradation 5/245 45/7206 0.0175877613466 ko00260 Glycine, serine and threonine metabolism 5/245 48/7206 0.0227163586151 ko04933 AGE-RAGE signaling pathway in diabetic complications 10/245 135/7206 0.0253774147846 ko05034 Alcoholism 2/245 238/7206 0.0262662577315 ko00380 Tryptophan metabolism 5/245 50/7206 0.0266227338292 ko05010 Alzheimer's disease 13/245 202/7206 0.0269284824485 ko00640 Propanoate metabolism 4/245 34/7206 0.0271667683965 ko04662 B cell receptor signaling pathway 7/245 88/7206 0.0296511739668 ko00627 Aminobenzoate degradation 2/245 9/7206 0.0353975321221 ko00930 Caprolactam degradation 2/245 9/7206 0.0353975321221 ko00280 Valine, leucine and isoleucine degradation 5/245 54/7206 0.0356591007975 ko05120 Epithelial cell signaling in Helicobacter pylori infection 7/245 92/7206 0.0365561227453 ko05205 Proteoglycans in cancer 16/245 271/7206 0.0374739011827 ko05416 Viral myocarditis 5/245 55/7206 0.0381799101533 ko04660 T cell receptor signaling pathway 9/245 124/7206 0.0382331527327 ko05134 Legionellosis 6/245 74/7206 0.0393535945826 ko05140 Leishmaniasis 6/245 75/7206 0.0416105195554 ko05211 Renal cell carcinoma 7/245 96/7206 0.0444481326436 ko04658 Th1 and Th2 cell differentiation 7/245 96/7206 0.0444481326436 ko04064 NF-kappa B signaling pathway 7/245 96/7206 0.0444481326436 ko04630 Jak-STAT signaling pathway 9/245 132/7206 0.0454772594187