ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	43/559	152/7206	1.97641192439e-14
ko05033	Nicotine addiction	24/559	56/7206	5.75665747019e-13
ko04080	Neuroactive ligand-receptor interaction	73/559	423/7206	2.79829089501e-11
ko04727	GABAergic synapse	31/559	110/7206	1.07904408138e-10
ko04728	Dopaminergic synapse	42/559	185/7206	1.11386947852e-10
ko04713	Circadian entrainment	30/559	136/7206	1.09616788376e-07
ko04723	Retrograde endocannabinoid signaling	35/559	175/7206	1.29116680481e-07
ko05032	Morphine addiction	26/559	110/7206	1.83648790465e-07
ko04744	Phototransduction	14/559	36/7206	1.8644104677e-07
ko04721	Synaptic vesicle cycle	21/559	80/7206	4.35103159796e-07
ko04740	Olfactory transduction	21/559	80/7206	4.35103159796e-07
ko04742	Taste transduction	18/559	61/7206	4.40355898053e-07
ko04725	Cholinergic synapse	32/559	160/7206	4.51282224819e-07
ko04260	Cardiac muscle contraction	23/559	98/7206	1.07719903934e-06
ko04974	Protein digestion and absorption	21/559	96/7206	1.03474081574e-05
ko04261	Adrenergic signaling in cardiomyocytes	34/559	205/7206	2.49653512613e-05
ko04911	Insulin secretion	23/559	117/7206	2.54171446713e-05
ko05164	Influenza A	1/559	167/7206	2.85073095183e-05
ko04060	Cytokine-cytokine receptor interaction	2/559	191/7206	4.79425860655e-05
ko05030	Cocaine addiction	16/559	73/7206	0.00011349073442
ko05031	Amphetamine addiction	18/559	91/7206	0.000175501040056
ko03040	Spliceosome	1/559	145/7206	0.000210356749868
ko04950	Maturity onset diabetes of the young	9/559	29/7206	0.000232991598385
ko04512	ECM-receptor interaction	16/559	79/7206	0.000300048467647
ko04976	Bile secretion	16/559	80/7206	0.00034877005747
ko05014	Amyotrophic lateral sclerosis (ALS)	15/559	74/7206	0.000455754406801
ko05168	Herpes simplex infection	3/559	182/7206	0.000597469055215
ko04978	Mineral absorption	10/559	40/7206	0.000731777603448
ko04726	Serotonergic synapse	22/559	137/7206	0.0009682491134
ko04024	cAMP signaling pathway	37/559	279/7206	0.00123134088979
ko05162	Measles	1/559	120/7206	0.00147791877972
ko04141	Protein processing in endoplasmic reticulum	4/559	184/7206	0.00186815988612
ko04120	Ubiquitin mediated proteolysis	2/559	138/7206	0.00193867232564
ko04151	PI3K-Akt signaling pathway	47/559	390/7206	0.00237413894651
ko00430	Taurine and hypotaurine metabolism	5/559	14/7206	0.0030614092706
ko05322	Systemic lupus erythematosus	3/559	151/7206	0.00328433548452
ko05016	Huntington's disease	6/559	215/7206	0.00394828145525
ko03013	RNA transport	4/559	166/7206	0.0049923506081
ko04964	Proximal tubule bicarbonate reclamation	7/559	29/7206	0.00563375986151
ko05203	Viral carcinogenesis	10/559	277/7206	0.00575575653214
ko00564	Glycerophospholipid metabolism	1/559	99/7206	0.00670744249471
ko04611	Platelet activation	4/559	163/7206	0.00698648462162
ko05166	HTLV-I infection	11/559	292/7206	0.00701160312208
ko04514	Cell adhesion molecules (CAMs)	19/559	130/7206	0.00704395435632
ko04140	Autophagy - animal	4/559	164/7206	0.00707107140794
ko04150	mTOR signaling pathway	5/559	184/7206	0.00724885266336
ko04621	NOD-like receptor signaling pathway	4/559	157/7206	0.00958273560063
ko04217	Necroptosis	5/559	178/7206	0.00979674528786
ko05410	Hypertrophic cardiomyopathy (HCM)	15/559	100/7206	0.0125407281806
ko05169	Epstein-Barr virus infection	7/559	206/7206	0.016377233007
ko05152	Tuberculosis	6/559	187/7206	0.0173753664784
ko05414	Dilated cardiomyopathy	16/559	112/7206	0.0183580393891
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	12/559	79/7206	0.0195243423073
ko04138	Autophagy - yeast	1/559	81/7206	0.0199388955739
ko04137	Mitophagy - animal	1/559	82/7206	0.0201483922928
ko03008	Ribosome biogenesis in eukaryotes	1/559	79/7206	0.0305241924736
ko00350	Tyrosine metabolism	6/559	33/7206	0.0388794788848
ko00830	Retinol metabolism	7/559	42/7206	0.0407862335817
ko04010	MAPK signaling pathway	35/559	321/7206	0.0415521033392
ko04113	Meiosis - yeast	1/559	70/7206	0.0417734578316
ko04214	Apoptosis - fly	1/559	72/7206	0.0425885541178
ko04142	Lysosome	5/559	151/7206	0.0435060053622
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/559	59/7206	0.0450055931342
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/559	182/7206	0.0480745003459
ko04144	Endocytosis	17/559	342/7206	0.0487205939808
ko04970	Salivary secretion	13/559	95/7206	0.0493936115995