ko pathway ratio_in_study ratio_in_pop p_value ko05032 Morphine addiction 18/190 110/7206 4.05790874747e-10 ko04744 Phototransduction 11/190 36/7206 1.08456040488e-09 ko04727 GABAergic synapse 17/190 110/7206 3.17446796114e-09 ko04740 Olfactory transduction 14/190 80/7206 1.59577620011e-08 ko04723 Retrograde endocannabinoid signaling 20/190 175/7206 2.65697280069e-08 ko05033 Nicotine addiction 11/190 56/7206 1.69575659036e-07 ko04728 Dopaminergic synapse 19/190 185/7206 3.3459752712e-07 ko04713 Circadian entrainment 15/190 136/7206 2.51024793837e-06 ko04726 Serotonergic synapse 15/190 137/7206 2.75440925121e-06 ko04725 Cholinergic synapse 16/190 160/7206 4.22401484482e-06 ko04080 Neuroactive ligand-receptor interaction 27/190 423/7206 2.35049183371e-05 ko04742 Taste transduction 9/190 61/7206 2.70321079891e-05 ko04724 Glutamatergic synapse 14/190 152/7206 4.35393228481e-05 ko04721 Synaptic vesicle cycle 9/190 80/7206 0.000234850125628 ko04974 Protein digestion and absorption 9/190 96/7206 0.000914259236322 ko04512 ECM-receptor interaction 7/190 79/7206 0.00463461974111 ko04151 PI3K-Akt signaling pathway 20/190 390/7206 0.00480052819429 ko04062 Chemokine signaling pathway 12/190 201/7206 0.00671719341723 ko05166 HTLV-I infection 1/190 292/7206 0.00752314674346 ko05014 Amyotrophic lateral sclerosis (ALS) 6/190 74/7206 0.0130353865014 ko04730 Long-term depression 6/190 78/7206 0.0165855552494 ko04978 Mineral absorption 4/190 40/7206 0.0204171861105 ko00830 Retinol metabolism 4/190 42/7206 0.0240145953164 ko04371 Apelin signaling pathway 10/190 177/7206 0.026689103716 ko05203 Viral carcinogenesis 2/190 277/7206 0.0350364985709 ko04964 Proximal tubule bicarbonate reclamation 3/190 29/7206 0.0398802047151 ko05169 Epstein-Barr virus infection 1/190 206/7206 0.04537290366