ko pathway ratio_in_study ratio_in_pop p_value ko05217 Basal cell carcinoma 27/310 68/7206 5.82988326268e-20 ko04550 Signaling pathways regulating pluripotency of stem cells 31/310 165/7206 1.85793837031e-12 ko05224 Breast cancer 30/310 174/7206 4.20426616317e-11 ko04340 Hedgehog signaling pathway 17/310 58/7206 1.52502608612e-10 ko04390 Hippo signaling pathway 30/310 188/7206 3.06018339544e-10 ko05200 Pathways in cancer 51/310 492/7206 2.27710377347e-09 ko03030 DNA replication 13/310 38/7206 2.76162400656e-09 ko04310 Wnt signaling pathway 27/310 181/7206 1.12291919497e-08 ko05205 Proteoglycans in cancer 34/310 271/7206 1.27996866508e-08 ko04080 Neuroactive ligand-receptor interaction 1/310 423/7206 1.80403752906e-07 ko04360 Axon guidance 27/310 233/7206 2.14630816159e-06 ko03410 Base excision repair 9/310 38/7206 2.42826648045e-05 ko04330 Notch signaling pathway 11/310 62/7206 5.56517105905e-05 ko04916 Melanogenesis 17/310 142/7206 0.000115586230699 ko04110 Cell cycle 17/310 145/7206 0.000149857030585 ko05166 HTLV-I infection 27/310 292/7206 0.000159463870601 ko04950 Maturity onset diabetes of the young 7/310 29/7206 0.000175431625554 ko05222 Small cell lung cancer 12/310 89/7206 0.000392054893751 ko04350 TGF-beta signaling pathway 13/310 103/7206 0.000437277192299 ko05202 Transcriptional misregulation in cancer 19/310 188/7206 0.000667080821125 ko04921 Oxytocin signaling pathway 1/310 209/7206 0.00158140826734 ko04062 Chemokine signaling pathway 1/310 201/7206 0.00231311449046 ko05206 MicroRNAs in cancer 16/310 177/7206 0.00422932085997 ko04020 Calcium signaling pathway 3/310 265/7206 0.00503528701075 ko04612 Antigen processing and presentation 9/310 77/7206 0.00551755758396 ko04144 Endocytosis 5/310 342/7206 0.00567868564223 ko04910 Insulin signaling pathway 1/310 172/7206 0.00711758316602 ko00240 Pyrimidine metabolism 11/310 110/7206 0.00746716819743 ko05418 Fluid shear stress and atherosclerosis 15/310 173/7206 0.0114710251345 ko04218 Cellular senescence 15/310 177/7206 0.0125440112958 ko04072 Phospholipase D signaling pathway 2/310 197/7206 0.0184483029696 ko04512 ECM-receptor interaction 8/310 79/7206 0.0197052635502 ko04341 Hedgehog signaling pathway - fly 5/310 38/7206 0.0223378380428 ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 4/310 26/7206 0.0237616634805 ko05168 Herpes simplex infection 2/310 182/7206 0.0249512562892 ko04022 cGMP-PKG signaling pathway 3/310 216/7206 0.0260599387992 ko00230 Purine metabolism 15/310 194/7206 0.0285017346536 ko04726 Serotonergic synapse 1/310 137/7206 0.0312696082455 ko03020 RNA polymerase 4/310 29/7206 0.0341528243262 ko04723 Retrograde endocannabinoid signaling 2/310 175/7206 0.0354136301911 ko00514 Other types of O-glycan biosynthesis 4/310 30/7206 0.0381177790668 ko04150 mTOR signaling pathway 14/310 184/7206 0.0394188474104 ko01522 Endocrine resistance 10/310 124/7206 0.0446039836217 ko00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 3/310 19/7206 0.0458436097012 ko04630 Jak-STAT signaling pathway 1/310 132/7206 0.0465634163506 ko04725 Cholinergic synapse 2/310 160/7206 0.0487040824123