ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	15/293	56/7206	3.46431540853e-09
ko04724	Glutamatergic synapse	24/293	152/7206	8.14521398399e-09
ko04080	Neuroactive ligand-receptor interaction	42/293	423/7206	5.85014847647e-08
ko04727	GABAergic synapse	19/293	110/7206	7.09200250594e-08
ko04911	Insulin secretion	19/293	117/7206	1.96285689225e-07
ko05032	Morphine addiction	18/293	110/7206	3.68741613999e-07
ko04723	Retrograde endocannabinoid signaling	23/293	175/7206	5.36548151977e-07
ko04726	Serotonergic synapse	19/293	137/7206	2.3818623722e-06
ko04721	Synaptic vesicle cycle	14/293	80/7206	3.31320062443e-06
ko04725	Cholinergic synapse	20/293	160/7206	6.59943057836e-06
ko04970	Salivary secretion	14/293	95/7206	2.58996882816e-05
ko04742	Taste transduction	11/293	61/7206	2.82864871391e-05
ko04020	Calcium signaling pathway	26/293	265/7206	3.82522144597e-05
ko04070	Phosphatidylinositol signaling system	15/293	112/7206	4.2601076529e-05
ko04072	Phospholipase D signaling pathway	21/293	197/7206	4.56783862259e-05
ko04010	MAPK signaling pathway	29/293	321/7206	5.78390342073e-05
ko04713	Circadian entrainment	16/293	136/7206	0.000117069589589
ko04720	Long-term potentiation	13/293	99/7206	0.00016926903159
ko04925	Aldosterone synthesis and secretion	13/293	105/7206	0.000306997378758
ko04921	Oxytocin signaling pathway	20/293	209/7206	0.000454821691059
ko04024	cAMP signaling pathway	24/293	279/7206	0.000489575010184
ko04972	Pancreatic secretion	13/293	111/7206	0.000530799038654
ko04964	Proximal tubule bicarbonate reclamation	6/293	29/7206	0.000923793632953
ko04730	Long-term depression	10/293	78/7206	0.00114790645067
ko04710	Circadian rhythm	7/293	43/7206	0.00156322587333
ko04728	Dopaminergic synapse	17/293	185/7206	0.00176577187373
ko04744	Phototransduction	6/293	36/7206	0.00298289586169
ko05169	Epstein-Barr virus infection	1/293	206/7206	0.00344593360412
ko04022	cGMP-PKG signaling pathway	18/293	216/7206	0.00409944164496
ko04151	PI3K-Akt signaling pathway	6/293	390/7206	0.0054481028539
ko04261	Adrenergic signaling in cardiomyocytes	17/293	205/7206	0.00577305937525
ko04930	Type II diabetes mellitus	7/293	54/7206	0.00587226656915
ko05200	Pathways in cancer	9/293	492/7206	0.00627181622451
ko04141	Protein processing in endoplasmic reticulum	1/293	184/7206	0.00717660883219
ko05203	Viral carcinogenesis	3/293	277/7206	0.00735133395819
ko00562	Inositol phosphate metabolism	9/293	89/7206	0.00985178159073
ko05161	Hepatitis B	1/293	173/7206	0.010371485279
ko05224	Breast cancer	1/293	174/7206	0.0103995639043
ko04217	Necroptosis	1/293	178/7206	0.0106998169197
ko05166	HTLV-I infection	4/293	292/7206	0.0142819309188
ko04145	Phagosome	1/293	162/7206	0.0149945510938
ko04550	Signaling pathways regulating pluripotency of stem cells	1/293	165/7206	0.0151042841848
ko04976	Bile secretion	8/293	80/7206	0.015545522645
ko04750	Inflammatory mediator regulation of TRP channels	11/293	122/7206	0.0166209535266
ko00604	Glycosphingolipid biosynthesis - ganglio series	3/293	14/7206	0.0173525590182
ko04971	Gastric acid secretion	9/293	98/7206	0.0177921404126
ko04621	NOD-like receptor signaling pathway	1/293	157/7206	0.0220737124983
ko04960	Aldosterone-regulated sodium reabsorption	5/293	41/7206	0.0242838309634
ko05167	Kaposi's sarcoma-associated herpesvirus infection	2/293	191/7206	0.024944812279
ko05030	Cocaine addiction	7/293	73/7206	0.0281933244275
ko05031	Amphetamine addiction	8/293	91/7206	0.0311747267062
ko04110	Cell cycle	1/293	145/7206	0.0313881765708
ko04961	Endocrine and other factor-regulated calcium reabsorption	6/293	59/7206	0.0317865110713
ko05168	Herpes simplex infection	2/293	182/7206	0.0350352029995
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/293	182/7206	0.0350352029995
ko05152	Tuberculosis	2/293	187/7206	0.0359796833029
ko04540	Gap junction	10/293	128/7206	0.0398921117121
ko00901	Indole alkaloid biosynthesis	1/293	1/7206	0.0406605606441
ko02025	Biofilm formation - Pseudomonas aeruginosa	1/293	1/7206	0.0406605606441
ko04380	Osteoclast differentiation	1/293	134/7206	0.044942805066
ko04120	Ubiquitin mediated proteolysis	1/293	138/7206	0.045971121215