ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	134/839	423/7206	3.13557378159e-30
ko04724	Glutamatergic synapse	69/839	152/7206	4.64888677389e-26
ko05033	Nicotine addiction	37/839	56/7206	6.46871828073e-22
ko04713	Circadian entrainment	55/839	136/7206	4.07723362787e-18
ko04020	Calcium signaling pathway	81/839	265/7206	2.57896631275e-17
ko05032	Morphine addiction	46/839	110/7206	5.19804704852e-16
ko04721	Synaptic vesicle cycle	37/839	80/7206	8.20230943383e-15
ko04727	GABAergic synapse	44/839	110/7206	1.6043521728e-14
ko04728	Dopaminergic synapse	60/839	185/7206	2.26566325545e-14
ko04024	cAMP signaling pathway	78/839	279/7206	2.62259715019e-14
ko04723	Retrograde endocannabinoid signaling	57/839	175/7206	8.45332637619e-14
ko04744	Phototransduction	23/839	36/7206	1.30629116342e-13
ko04911	Insulin secretion	44/839	117/7206	2.17693566424e-13
ko04725	Cholinergic synapse	52/839	160/7206	1.19238252707e-12
ko04921	Oxytocin signaling pathway	60/839	209/7206	1.25446056317e-11
ko04726	Serotonergic synapse	44/839	137/7206	1.05469876586e-10
ko04720	Long-term potentiation	35/839	99/7206	4.76069655458e-10
ko05031	Amphetamine addiction	33/839	91/7206	7.02072869809e-10
ko04970	Salivary secretion	31/839	95/7206	4.15102334135e-08
ko04925	Aldosterone synthesis and secretion	33/839	105/7206	4.28052491964e-08
ko04261	Adrenergic signaling in cardiomyocytes	51/839	205/7206	9.37707499641e-08
ko04742	Taste transduction	23/839	61/7206	1.19936201247e-07
ko04070	Phosphatidylinositol signaling system	32/839	112/7206	7.80595454695e-07
ko04745	Phototransduction - fly	16/839	38/7206	1.83574957946e-06
ko05322	Systemic lupus erythematosus	2/839	151/7206	2.28806225911e-06
ko03010	Ribosome	1/839	129/7206	2.75528541265e-06
ko04971	Gastric acid secretion	28/839	98/7206	3.8097036086e-06
ko04022	cGMP-PKG signaling pathway	49/839	216/7206	4.00392481508e-06
ko04730	Long-term depression	24/839	78/7206	4.55672349724e-06
ko05030	Cocaine addiction	23/839	73/7206	4.5938909928e-06
ko03040	Spliceosome	2/839	145/7206	5.07819894938e-06
ko04010	MAPK signaling pathway	64/839	321/7206	1.05786260635e-05
ko04750	Inflammatory mediator regulation of TRP channels	31/839	122/7206	2.07861872052e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	22/839	74/7206	2.08105517982e-05
ko05169	Epstein-Barr virus infection	7/839	206/7206	3.51247614784e-05
ko05168	Herpes simplex infection	6/839	182/7206	8.84283243022e-05
ko04072	Phospholipase D signaling pathway	42/839	197/7206	0.00010101791286
ko04972	Pancreatic secretion	27/839	111/7206	0.000144132094241
ko05203	Viral carcinogenesis	14/839	277/7206	0.000176769961305
ko04110	Cell cycle	4/839	145/7206	0.000193591140742
ko04710	Circadian rhythm	14/839	43/7206	0.000229729609202
ko03013	RNA transport	6/839	166/7206	0.000337335939222
ko05164	Influenza A	6/839	167/7206	0.000338745317197
ko05162	Measles	3/839	120/7206	0.000463796928676
ko04626	Plant-pathogen interaction	8/839	18/7206	0.000489316746723
ko04060	Cytokine-cytokine receptor interaction	8/839	191/7206	0.000515946172803
ko04740	Olfactory transduction	20/839	80/7206	0.000690320172559
ko04922	Glucagon signaling pathway	28/839	128/7206	0.000753990270651
ko04260	Cardiac muscle contraction	23/839	98/7206	0.000756325732613
ko04924	Renin secretion	21/839	86/7206	0.000943611972139
ko04141	Protein processing in endoplasmic reticulum	8/839	184/7206	0.000970149841193
ko03008	Ribosome biogenesis in eukaryotes	1/839	79/7206	0.00115739905752
ko04120	Ubiquitin mediated proteolysis	5/839	138/7206	0.00119888092362
ko05130	Pathogenic Escherichia coli infection	1/839	77/7206	0.00180756445715
ko04612	Antigen processing and presentation	1/839	77/7206	0.00180756445715
ko04966	Collecting duct acid secretion	9/839	26/7206	0.00186942039374
ko04540	Gap junction	27/839	128/7206	0.00192462412932
ko04621	NOD-like receptor signaling pathway	7/839	157/7206	0.00238615613515
ko05200	Pathways in cancer	37/839	492/7206	0.00273397985561
ko04014	Ras signaling pathway	49/839	279/7206	0.00299067255475
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/839	14/7206	0.0032157140925
ko04964	Proximal tubule bicarbonate reclamation	9/839	29/7206	0.0043466969209
ko04514	Cell adhesion molecules (CAMs)	26/839	130/7206	0.00526441546053
ko04510	Focal adhesion	15/839	240/7206	0.00564102139406
ko04064	NF-kappa B signaling pathway	3/839	96/7206	0.00569439622944
ko05166	HTLV-I infection	20/839	292/7206	0.00685141998947
ko00562	Inositol phosphate metabolism	19/839	89/7206	0.0072569999361
ko04930	Type II diabetes mellitus	13/839	54/7206	0.00891238787909
ko05140	Leishmaniasis	2/839	75/7206	0.0101578267573
ko05160	Hepatitis C	8/839	153/7206	0.0102337424123
ko04657	IL-17 signaling pathway	3/839	87/7206	0.0111194591361
ko05222	Small cell lung cancer	3/839	89/7206	0.0113792261799
ko05161	Hepatitis B	10/839	173/7206	0.011534652114
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/839	79/7206	0.01189952799
ko04915	Estrogen signaling pathway	25/839	131/7206	0.0124380508767
ko00680	Methane metabolism	9/839	34/7206	0.0133797638225
ko04114	Oocyte meiosis	26/839	139/7206	0.0152128703263
ko05110	Vibrio cholerae infection	14/839	63/7206	0.0157235018794
ko00010	Glycolysis / Gluconeogenesis	16/839	74/7206	0.0157473956703
ko04371	Apelin signaling pathway	31/839	177/7206	0.0174304412063
ko04630	Jak-STAT signaling pathway	7/839	132/7206	0.0191870951445
ko05217	Basal cell carcinoma	2/839	68/7206	0.0208645366871
ko00230	Purine metabolism	33/839	194/7206	0.0228380365706
ko04960	Aldosterone-regulated sodium reabsorption	10/839	41/7206	0.0229258237936
ko05224	Breast cancer	11/839	174/7206	0.0229457187483
ko05414	Dilated cardiomyopathy	21/839	112/7206	0.0249049762619
ko05010	Alzheimer's disease	34/839	202/7206	0.0254529864865
ko05205	Proteoglycans in cancer	20/839	271/7206	0.0258920499905
ko04360	Axon guidance	38/839	233/7206	0.0288626152602
ko04610	Complement and coagulation cascades	3/839	79/7206	0.0317719210962
ko03420	Nucleotide excision repair	1/839	46/7206	0.0378655698466
ko05219	Bladder cancer	1/839	48/7206	0.038653805076
ko04214	Apoptosis - fly	3/839	72/7206	0.0423340481573
ko04151	PI3K-Akt signaling pathway	33/839	390/7206	0.0425082692712
ko04330	Notch signaling pathway	2/839	62/7206	0.0432889707635
ko04622	RIG-I-like receptor signaling pathway	2/839	62/7206	0.0432889707635
ko04668	TNF signaling pathway	7/839	120/7206	0.044058828212