ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	65/415	145/7206	4.53421671173e-43
ko03030	DNA replication	26/415	38/7206	3.93316277649e-24
ko03050	Proteasome	27/415	54/7206	6.86370883549e-20
ko03013	RNA transport	40/415	166/7206	2.50787803158e-15
ko00240	Pyrimidine metabolism	31/415	110/7206	4.00039220799e-14
ko03430	Mismatch repair	14/415	22/7206	7.47137427042e-13
ko04110	Cell cycle	33/415	145/7206	4.30478196551e-12
ko03410	Base excision repair	17/415	38/7206	5.74812313114e-12
ko03420	Nucleotide excision repair	18/415	46/7206	2.13803177367e-11
ko03020	RNA polymerase	14/415	29/7206	1.24724922528e-10
ko04080	Neuroactive ligand-receptor interaction	1/415	423/7206	2.50060022323e-10
ko05169	Epstein-Barr virus infection	37/415	206/7206	3.42955824802e-10
ko04111	Cell cycle - yeast	23/415	90/7206	7.35782927739e-10
ko03015	mRNA surveillance pathway	23/415	93/7206	1.48428875461e-09
ko03460	Fanconi anemia pathway	15/415	51/7206	9.29498949555e-08
ko04113	Meiosis - yeast	17/415	70/7206	2.83252150437e-07
ko00230	Purine metabolism	29/415	194/7206	1.72915564884e-06
ko03022	Basal transcription factors	12/415	44/7206	4.4393664774e-06
ko03008	Ribosome biogenesis in eukaryotes	16/415	79/7206	8.23892379971e-06
ko03018	RNA degradation	16/415	84/7206	1.86948591635e-05
ko04144	Endocytosis	4/415	342/7206	2.22413896909e-05
ko04020	Calcium signaling pathway	2/415	265/7206	3.68832906845e-05
ko04010	MAPK signaling pathway	4/415	321/7206	6.51515623504e-05
ko03440	Homologous recombination	10/415	41/7206	8.04036728205e-05
ko04120	Ubiquitin mediated proteolysis	20/415	138/7206	0.000111695365715
ko04360	Axon guidance	2/415	233/7206	0.000160487166557
ko05168	Herpes simplex infection	23/415	182/7206	0.000306879227203
ko04022	cGMP-PKG signaling pathway	2/415	216/7206	0.00049876895617
ko04024	cAMP signaling pathway	4/415	279/7206	0.000531188298225
ko04921	Oxytocin signaling pathway	2/415	209/7206	0.000719059302369
ko04723	Retrograde endocannabinoid signaling	1/415	175/7206	0.000746046818036
ko04060	Cytokine-cytokine receptor interaction	2/415	191/7206	0.00145014712847
ko04014	Ras signaling pathway	5/415	279/7206	0.00152339591667
ko03060	Protein export	6/415	23/7206	0.00153408669868
ko04725	Cholinergic synapse	1/415	160/7206	0.00156364416522
ko04623	Cytosolic DNA-sensing pathway	8/415	41/7206	0.00201152871414
ko04724	Glutamatergic synapse	1/415	152/7206	0.0022520647778
ko05012	Parkinson's disease	1/415	155/7206	0.00236861804088
ko04510	Focal adhesion	4/415	240/7206	0.0027623261443
ko04810	Regulation of actin cytoskeleton	5/415	264/7206	0.00289486962875
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/415	182/7206	0.00309427791382
ko04261	Adrenergic signaling in cardiomyocytes	3/415	205/7206	0.0035002998088
ko04933	AGE-RAGE signaling pathway in diabetic complications	1/415	135/7206	0.0047218275181
ko04713	Circadian entrainment	1/415	136/7206	0.0047229441004
ko04931	Insulin resistance	1/415	137/7206	0.00474249942017
ko04726	Serotonergic synapse	1/415	137/7206	0.00474249942017
ko04062	Chemokine signaling pathway	3/415	201/7206	0.00501518516967
ko04015	Rap1 signaling pathway	6/415	278/7206	0.00543715838615
ko04712	Circadian rhythm - plant	3/415	7/7206	0.00557615185818
ko04550	Signaling pathways regulating pluripotency of stem cells	2/415	165/7206	0.00608916626865
ko04068	FoxO signaling pathway	2/415	167/7206	0.00620580459036
ko04922	Glucagon signaling pathway	1/415	128/7206	0.00687016099223
ko04514	Cell adhesion molecules (CAMs)	1/415	130/7206	0.0068976004351
ko04915	Estrogen signaling pathway	1/415	131/7206	0.00695065319637
ko04630	Jak-STAT signaling pathway	1/415	132/7206	0.00703024058583
ko04380	Osteoclast differentiation	1/415	134/7206	0.00727023935752
ko05231	Choline metabolism in cancer	1/415	134/7206	0.00727023935752
ko04912	GnRH signaling pathway	1/415	122/7206	0.00997918694077
ko03010	Ribosome	15/415	129/7206	0.011025792028
ko04670	Leukocyte transendothelial migration	2/415	151/7206	0.0122726950162
ko04270	Vascular smooth muscle contraction	2/415	154/7206	0.0126792602143
ko04371	Apelin signaling pathway	3/415	177/7206	0.0133657894419
ko04668	TNF signaling pathway	1/415	120/7206	0.0152478461884
ko04012	ErbB signaling pathway	1/415	109/7206	0.0210124166624
ko04727	GABAergic synapse	1/415	110/7206	0.0211582441557
ko05032	Morphine addiction	1/415	110/7206	0.0211582441557
ko04070	Phosphatidylinositol signaling system	1/415	112/7206	0.0216659314827
ko05205	Proteoglycans in cancer	7/415	271/7206	0.0225808474517
ko04152	AMPK signaling pathway	3/415	161/7206	0.0254993177609
ko04620	Toll-like receptor signaling pathway	1/415	100/7206	0.0302326892076
ko04659	Th17 cell differentiation	1/415	106/7206	0.0317660433265
ko01200	Carbon metabolism	2/415	128/7206	0.034075466597
ko05200	Pathways in cancer	18/415	492/7206	0.0353141533
ko04728	Dopaminergic synapse	4/415	185/7206	0.0354473375475
ko04621	NOD-like receptor signaling pathway	3/415	157/7206	0.0355429208259
ko04115	p53 signaling pathway	9/415	74/7206	0.0375617588408
ko04114	Oocyte meiosis	14/415	139/7206	0.0400574789718
ko05211	Renal cell carcinoma	1/415	96/7206	0.0440327749902
ko05132	Salmonella infection	1/415	98/7206	0.0450212376916
ko05146	Amoebiasis	1/415	99/7206	0.0457160762918
ko04910	Insulin signaling pathway	4/415	172/7206	0.0465485238101
ko05224	Breast cancer	4/415	174/7206	0.0466926568525
ko04750	Inflammatory mediator regulation of TRP channels	2/415	122/7206	0.0478868739031
ko04666	Fc gamma R-mediated phagocytosis	2/415	122/7206	0.0478868739031
ko04660	T cell receptor signaling pathway	2/415	124/7206	0.0485856066709
ko05145	Toxoplasmosis	2/415	126/7206	0.0497303633602