ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	175/939	423/7206	1.45287720039e-51
ko04724	Glutamatergic synapse	82/939	152/7206	3.50960125282e-34
ko05033	Nicotine addiction	47/939	56/7206	2.14399117064e-33
ko05032	Morphine addiction	62/939	110/7206	1.84688529679e-27
ko04727	GABAergic synapse	60/939	110/7206	1.44202220402e-25
ko04728	Dopaminergic synapse	74/939	185/7206	1.13047061507e-20
ko04723	Retrograde endocannabinoid signaling	71/939	175/7206	2.73005085918e-20
ko04713	Circadian entrainment	60/939	136/7206	1.83536447974e-19
ko04725	Cholinergic synapse	65/939	160/7206	1.07308745338e-18
ko04024	cAMP signaling pathway	90/939	279/7206	1.91975384052e-17
ko04721	Synaptic vesicle cycle	41/939	80/7206	1.5366395462e-16
ko04911	Insulin secretion	49/939	117/7206	5.2889131243e-15
ko04726	Serotonergic synapse	52/939	137/7206	9.38201643705e-14
ko04020	Calcium signaling pathway	78/939	265/7206	6.1867958427e-13
ko04742	Taste transduction	31/939	61/7206	1.09124259914e-12
ko04744	Phototransduction	21/939	36/7206	1.69325195727e-10
ko04261	Adrenergic signaling in cardiomyocytes	60/939	205/7206	5.25325267911e-10
ko04921	Oxytocin signaling pathway	60/939	209/7206	9.99092001529e-10
ko04360	Axon guidance	65/939	233/7206	1.0019666479e-09
ko05031	Amphetamine addiction	34/939	91/7206	3.1334922832e-09
ko05030	Cocaine addiction	29/939	73/7206	8.95469312709e-09
ko03040	Spliceosome	1/939	145/7206	5.80620367577e-08
ko05203	Viral carcinogenesis	10/939	277/7206	8.34381743895e-08
ko04720	Long-term potentiation	32/939	99/7206	4.59361788375e-07
ko04970	Salivary secretion	30/939	95/7206	1.81979227815e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/939	74/7206	3.36591628588e-06
ko04514	Cell adhesion molecules (CAMs)	36/939	130/7206	7.98620002662e-06
ko04010	MAPK signaling pathway	70/939	321/7206	8.4622199137e-06
ko05168	Herpes simplex infection	6/939	182/7206	9.68815348373e-06
ko04972	Pancreatic secretion	32/939	111/7206	1.03378353999e-05
ko03013	RNA transport	5/939	166/7206	1.15080944925e-05
ko05164	Influenza A	5/939	167/7206	1.16587114844e-05
ko05322	Systemic lupus erythematosus	4/939	151/7206	1.32725195062e-05
ko04060	Cytokine-cytokine receptor interaction	7/939	191/7206	1.58437932737e-05
ko04141	Protein processing in endoplasmic reticulum	7/939	184/7206	3.12550476988e-05
ko04022	cGMP-PKG signaling pathway	50/939	216/7206	3.28775135147e-05
ko04925	Aldosterone synthesis and secretion	29/939	105/7206	5.40028247734e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/939	79/7206	5.49200838234e-05
ko04120	Ubiquitin mediated proteolysis	4/939	138/7206	5.79122559347e-05
ko05205	Proteoglycans in cancer	15/939	271/7206	6.51540840116e-05
ko04260	Cardiac muscle contraction	27/939	98/7206	0.000106410986995
ko04971	Gastric acid secretion	27/939	98/7206	0.000106410986995
ko04072	Phospholipase D signaling pathway	45/939	197/7206	0.000141461686234
ko04621	NOD-like receptor signaling pathway	6/939	157/7206	0.000160710247285
ko05414	Dilated cardiomyopathy	29/939	112/7206	0.000190266255977
ko04730	Long-term depression	22/939	78/7206	0.000291912420628
ko03008	Ribosome biogenesis in eukaryotes	1/939	79/7206	0.000316067512764
ko04540	Gap junction	31/939	128/7206	0.000475263891064
ko05162	Measles	4/939	120/7206	0.000510287842752
ko05161	Hepatitis B	9/939	173/7206	0.000858595750229
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/939	14/7206	0.000930450501437
ko05169	Epstein-Barr virus infection	12/939	206/7206	0.00103073148814
ko04915	Estrogen signaling pathway	30/939	131/7206	0.00153278282621
ko04140	Autophagy - animal	9/939	164/7206	0.00212287596652
ko04070	Phosphatidylinositol signaling system	26/939	112/7206	0.00266747440748
ko04612	Antigen processing and presentation	2/939	77/7206	0.00320110265119
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/939	182/7206	0.00345226607818
ko04014	Ras signaling pathway	53/939	279/7206	0.00364568251174
ko04110	Cell cycle	8/939	145/7206	0.00400764111151
ko04966	Collecting duct acid secretion	9/939	26/7206	0.00409882646349
ko04217	Necroptosis	11/939	178/7206	0.00451442402632
ko05140	Leishmaniasis	2/939	75/7206	0.00484304489848
ko03018	RNA degradation	3/939	84/7206	0.00525829217687
ko04064	NF-kappa B signaling pathway	4/939	96/7206	0.00564056231385
ko04630	Jak-STAT signaling pathway	7/939	132/7206	0.00567428693995
ko00240	Pyrimidine metabolism	5/939	110/7206	0.00600118426107
ko04976	Bile secretion	19/939	80/7206	0.00716042724536
ko00280	Valine, leucine and isoleucine degradation	1/939	54/7206	0.00766738786104
ko00480	Glutathione metabolism	1/939	55/7206	0.0077419444419
ko05321	Inflammatory bowel disease (IBD)	1/939	56/7206	0.00798538560709
ko04924	Renin secretion	20/939	86/7206	0.00887623666585
ko04964	Proximal tubule bicarbonate reclamation	9/939	29/7206	0.00916079829718
ko04218	Cellular senescence	12/939	177/7206	0.00922482463322
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/939	59/7206	0.00979007620573
ko04923	Regulation of lipolysis in adipocytes	18/939	77/7206	0.0103948688053
ko00590	Arachidonic acid metabolism	1/939	52/7206	0.0114967209938
ko04640	Hematopoietic cell lineage	2/939	64/7206	0.013892852542
ko05215	Prostate cancer	6/939	111/7206	0.0147169359295
ko04740	Olfactory transduction	18/939	80/7206	0.0179999345812
ko00330	Arginine and proline metabolism	2/939	61/7206	0.0200298560785
ko04214	Apoptosis - fly	3/939	72/7206	0.0210001496496
ko05110	Vibrio cholerae infection	15/939	63/7206	0.0215307476284
ko04930	Type II diabetes mellitus	13/939	54/7206	0.0236444216175
ko05410	Hypertrophic cardiomyopathy (HCM)	21/939	100/7206	0.0238136988083
ko05034	Alcoholism	43/939	238/7206	0.0238818361026
ko05144	Malaria	1/939	45/7206	0.0247977892883
ko00071	Fatty acid degradation	1/939	45/7206	0.0247977892883
ko03420	Nucleotide excision repair	1/939	46/7206	0.0252473287402
ko00270	Cysteine and methionine metabolism	1/939	47/7206	0.026177823739
ko05418	Fluid shear stress and atherosclerosis	13/939	173/7206	0.0291804258182
ko05131	Shigellosis	4/939	82/7206	0.0299212157092
ko04210	Apoptosis	14/939	180/7206	0.0327764985565
ko04918	Thyroid hormone synthesis	18/939	86/7206	0.0354712071503
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/939	15/7206	0.0363131153522
ko00140	Steroid hormone biosynthesis	1/939	41/7206	0.0364811091623
ko00983	Drug metabolism - other enzymes	1/939	42/7206	0.0365670608617
ko04657	IL-17 signaling pathway	5/939	87/7206	0.0376140370797
ko05133	Pertussis	5/939	87/7206	0.0376140370797
ko04146	Peroxisome	5/939	89/7206	0.0378957787104
ko03022	Basal transcription factors	1/939	44/7206	0.0387398309852
ko05016	Huntington's disease	18/939	215/7206	0.0393347546627
ko01524	Platinum drug resistance	4/939	76/7206	0.039657020198
ko04750	Inflammatory mediator regulation of TRP channels	24/939	122/7206	0.0403377902736
ko05145	Toxoplasmosis	9/939	126/7206	0.0453226669009
ko01200	Carbon metabolism	9/939	128/7206	0.0456853787242
ko04150	mTOR signaling pathway	15/939	184/7206	0.0457036174232
ko04658	Th1 and Th2 cell differentiation	6/939	96/7206	0.0466177231705
ko04068	FoxO signaling pathway	13/939	167/7206	0.0469564628864
ko04962	Vasopressin-regulated water reabsorption	13/939	58/7206	0.0469982296022