ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	163/911	423/7206	8.30006319897e-45
ko04724	Glutamatergic synapse	82/911	152/7206	3.55776813461e-35
ko05033	Nicotine addiction	47/911	56/7206	5.18101288954e-34
ko05032	Morphine addiction	60/911	110/7206	2.74783937333e-26
ko04727	GABAergic synapse	59/911	110/7206	2.38092087819e-25
ko04713	Circadian entrainment	60/911	136/7206	3.92014450127e-20
ko04723	Retrograde endocannabinoid signaling	69/911	175/7206	1.13003195793e-19
ko04721	Synaptic vesicle cycle	43/911	80/7206	7.99277273018e-19
ko04728	Dopaminergic synapse	69/911	185/7206	4.0037965083e-18
ko04024	cAMP signaling pathway	89/911	279/7206	6.51231983492e-18
ko04725	Cholinergic synapse	60/911	160/7206	4.99934441131e-16
ko04911	Insulin secretion	48/911	117/7206	8.0123325714e-15
ko04742	Taste transduction	32/911	61/7206	6.23479901786e-14
ko04020	Calcium signaling pathway	77/911	265/7206	4.60840166075e-13
ko04726	Serotonergic synapse	49/911	137/7206	2.09292854544e-12
ko04921	Oxytocin signaling pathway	62/911	209/7206	4.08258163233e-11
ko04744	Phototransduction	21/911	36/7206	9.48496446233e-11
ko04720	Long-term potentiation	37/911	99/7206	2.59294753843e-10
ko05031	Amphetamine addiction	35/911	91/7206	3.17034856832e-10
ko04261	Adrenergic signaling in cardiomyocytes	58/911	205/7206	1.3132253277e-09
ko05203	Viral carcinogenesis	9/911	277/7206	5.35903445695e-08
ko05030	Cocaine addiction	27/911	73/7206	8.97377651468e-08
ko03040	Spliceosome	1/911	145/7206	9.05833975644e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	27/911	74/7206	1.2457591331e-07
ko04970	Salivary secretion	31/911	95/7206	2.77483760195e-07
ko05164	Influenza A	3/911	167/7206	7.09427054721e-07
ko04925	Aldosterone synthesis and secretion	32/911	105/7206	1.6269575363e-06
ko04360	Axon guidance	55/911	233/7206	2.81994833049e-06
ko05168	Herpes simplex infection	5/911	182/7206	4.06111422137e-06
ko04010	MAPK signaling pathway	68/911	321/7206	1.02043473076e-05
ko04972	Pancreatic secretion	31/911	111/7206	1.58559866472e-05
ko04260	Cardiac muscle contraction	28/911	98/7206	2.01983651566e-05
ko04971	Gastric acid secretion	28/911	98/7206	2.01983651566e-05
ko04514	Cell adhesion molecules (CAMs)	34/911	130/7206	2.39412223904e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/911	79/7206	2.39716022817e-05
ko03013	RNA transport	5/911	166/7206	2.5191969758e-05
ko05322	Systemic lupus erythematosus	4/911	151/7206	3.03236858668e-05
ko04060	Cytokine-cytokine receptor interaction	7/911	191/7206	3.33664683445e-05
ko04740	Olfactory transduction	24/911	80/7206	4.91151599401e-05
ko04621	NOD-like receptor signaling pathway	5/911	157/7206	5.02661393479e-05
ko04141	Protein processing in endoplasmic reticulum	7/911	184/7206	6.51430185082e-05
ko04022	cGMP-PKG signaling pathway	48/911	216/7206	6.55023424196e-05
ko04072	Phospholipase D signaling pathway	45/911	197/7206	7.15605128513e-05
ko05205	Proteoglycans in cancer	15/911	271/7206	0.000118618406086
ko05161	Hepatitis B	7/911	173/7206	0.000174279461368
ko04730	Long-term depression	22/911	78/7206	0.00020143792405
ko05169	Epstein-Barr virus infection	10/911	206/7206	0.000256170461496
ko05414	Dilated cardiomyopathy	28/911	112/7206	0.000279085120161
ko04120	Ubiquitin mediated proteolysis	5/911	138/7206	0.0004089862545
ko03008	Ribosome biogenesis in eukaryotes	1/911	79/7206	0.000488597892977
ko04745	Phototransduction - fly	13/911	38/7206	0.000498536459909
ko04540	Gap junction	30/911	128/7206	0.000657185783846
ko05162	Measles	4/911	120/7206	0.000738734355441
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/911	14/7206	0.00077240980326
ko04966	Collecting duct acid secretion	10/911	26/7206	0.000779723183444
ko00310	Lysine degradation	1/911	73/7206	0.00109650342714
ko05110	Vibrio cholerae infection	17/911	63/7206	0.00180041890722
ko04064	NF-kappa B signaling pathway	3/911	96/7206	0.002772985844
ko04640	Hematopoietic cell lineage	1/911	64/7206	0.00367824014568
ko04070	Phosphatidylinositol signaling system	25/911	112/7206	0.00377267134909
ko04140	Autophagy - animal	9/911	164/7206	0.00397892461923
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/911	182/7206	0.0045415288656
ko05140	Leishmaniasis	2/911	75/7206	0.00464891313273
ko01524	Platinum drug resistance	2/911	76/7206	0.00471951238962
ko04915	Estrogen signaling pathway	28/911	131/7206	0.00483369870867
ko04612	Antigen processing and presentation	2/911	77/7206	0.00487139339885
ko05215	Prostate cancer	5/911	111/7206	0.00588600028853
ko04210	Apoptosis	11/911	180/7206	0.00603604543354
ko05166	HTLV-I infection	22/911	292/7206	0.00673395052245
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	6/911	15/7206	0.00729953162049
ko04110	Cell cycle	8/911	145/7206	0.00746570476391
ko04964	Proximal tubule bicarbonate reclamation	9/911	29/7206	0.00752207602162
ko03018	RNA degradation	3/911	84/7206	0.00759534172704
ko04218	Cellular senescence	11/911	177/7206	0.0079619858895
ko04668	TNF signaling pathway	6/911	120/7206	0.00800240097389
ko00240	Pyrimidine metabolism	5/911	110/7206	0.00839800441379
ko05410	Hypertrophic cardiomyopathy (HCM)	22/911	100/7206	0.00900170687264
ko00590	Arachidonic acid metabolism	1/911	52/7206	0.0115436602351
ko00480	Glutathione metabolism	1/911	55/7206	0.0122672057366
ko04750	Inflammatory mediator regulation of TRP channels	25/911	122/7206	0.012764700085
ko04510	Focal adhesion	18/911	240/7206	0.0131999391753
ko04924	Renin secretion	19/911	86/7206	0.013229196429
ko05145	Toxoplasmosis	7/911	126/7206	0.0140763211401
ko04146	Peroxisome	4/911	89/7206	0.0154302849888
ko05222	Small cell lung cancer	4/911	89/7206	0.0154302849888
ko04976	Bile secretion	18/911	80/7206	0.0160948889274
ko04014	Ras signaling pathway	49/911	279/7206	0.0164583018831
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/911	59/7206	0.0166050764246
ko04630	Jak-STAT signaling pathway	8/911	132/7206	0.0172610526174
ko04150	mTOR signaling pathway	13/911	184/7206	0.0180931589944
ko00330	Arginine and proline metabolism	2/911	61/7206	0.0199939036719
ko05418	Fluid shear stress and atherosclerosis	12/911	173/7206	0.0201275619976
ko04930	Type II diabetes mellitus	13/911	54/7206	0.0207935158676
ko04670	Leukocyte transendothelial migration	10/911	151/7206	0.0249684635794
ko03420	Nucleotide excision repair	1/911	46/7206	0.0250553894123
ko05219	Bladder cancer	1/911	48/7206	0.0260356798486
ko04217	Necroptosis	13/911	178/7206	0.0294297621138
ko04214	Apoptosis - fly	3/911	72/7206	0.0302803104476
ko04350	TGF-beta signaling pathway	6/911	103/7206	0.0355082002087
ko05034	Alcoholism	41/911	238/7206	0.0367276909771
ko03022	Basal transcription factors	1/911	44/7206	0.0374188976826
ko04371	Apelin signaling pathway	32/911	177/7206	0.0382127522588
ko00071	Fatty acid degradation	1/911	45/7206	0.0385933956292
ko05321	Inflammatory bowel disease (IBD)	2/911	56/7206	0.0411137047305
ko03320	PPAR signaling pathway	3/911	69/7206	0.0424865484375
ko04620	Toll-like receptor signaling pathway	6/911	100/7206	0.0473823130871
ko00230	Purine metabolism	34/911	194/7206	0.0477469958326