ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	18/198	56/7206	3.12660780198e-15
ko04724	Glutamatergic synapse	26/198	152/7206	3.45971223812e-14
ko04727	GABAergic synapse	22/198	110/7206	1.31043358687e-13
ko04080	Neuroactive ligand-receptor interaction	37/198	423/7206	1.8212565243e-10
ko04723	Retrograde endocannabinoid signaling	22/198	175/7206	1.80842058959e-09
ko04728	Dopaminergic synapse	22/198	185/7206	5.21976954453e-09
ko05032	Morphine addiction	17/198	110/7206	5.97176220919e-09
ko04721	Synaptic vesicle cycle	14/198	80/7206	2.70512669898e-08
ko04024	cAMP signaling pathway	25/198	279/7206	1.43645650537e-07
ko04713	Circadian entrainment	17/198	136/7206	1.52250548315e-07
ko04725	Cholinergic synapse	17/198	160/7206	1.58748836091e-06
ko04726	Serotonergic synapse	15/198	137/7206	4.59898539615e-06
ko04911	Insulin secretion	13/198	117/7206	1.72631360311e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	10/198	74/7206	3.03633840961e-05
ko05031	Amphetamine addiction	11/198	91/7206	3.5361197982e-05
ko04360	Axon guidance	18/198	233/7206	6.67224140749e-05
ko05030	Cocaine addiction	8/198	73/7206	0.000820230917429
ko04010	MAPK signaling pathway	19/198	321/7206	0.00136613864675
ko04720	Long-term potentiation	9/198	99/7206	0.00152259412876
ko04514	Cell adhesion molecules (CAMs)	10/198	130/7206	0.00297408728029
ko04930	Type II diabetes mellitus	6/198	54/7206	0.00343734253515
ko04261	Adrenergic signaling in cardiomyocytes	13/198	205/7206	0.00413344463374
ko04961	Endocrine and other factor-regulated calcium reabsorption	6/198	59/7206	0.00535542096332
ko04742	Taste transduction	6/198	61/7206	0.00630821207235
ko04964	Proximal tubule bicarbonate reclamation	4/198	29/7206	0.00766602029352
ko04925	Aldosterone synthesis and secretion	8/198	105/7206	0.00807562757122
ko04072	Phospholipase D signaling pathway	12/198	197/7206	0.011733560494
ko04960	Aldosterone-regulated sodium reabsorption	4/198	41/7206	0.0253456635577
ko04973	Carbohydrate digestion and absorption	4/198	42/7206	0.0274298825947
ko04921	Oxytocin signaling pathway	11/198	209/7206	0.0315199542984
ko04972	Pancreatic secretion	7/198	111/7206	0.0327620992723