ko pathway ratio_in_study ratio_in_pop p_value ko04710 Circadian rhythm 18/633 43/7206 5.72704989785e-09 ko04070 Phosphatidylinositol signaling system 29/633 112/7206 6.32604192161e-08 ko04744 Phototransduction 14/633 36/7206 8.63633652399e-07 ko05032 Morphine addiction 25/633 110/7206 6.7886274054e-06 ko05322 Systemic lupus erythematosus 1/633 151/7206 2.77546725014e-05 ko03040 Spliceosome 1/633 145/7206 3.97522793726e-05 ko04060 Cytokine-cytokine receptor interaction 33/633 191/7206 0.000134183771711 ko04726 Serotonergic synapse 26/633 137/7206 0.000166384771561 ko03010 Ribosome 1/633 129/7206 0.000203170674789 ko04724 Glutamatergic synapse 27/633 152/7206 0.000380764134838 ko03013 RNA transport 3/633 166/7206 0.00040313802937 ko04080 Neuroactive ligand-receptor interaction 58/633 423/7206 0.000512869013516 ko04072 Phospholipase D signaling pathway 32/633 197/7206 0.00075211136087 ko04014 Ras signaling pathway 40/633 279/7206 0.00165383270073 ko05230 Central carbon metabolism in cancer 16/633 81/7206 0.00211448291052 ko04960 Aldosterone-regulated sodium reabsorption 10/633 41/7206 0.00232544001737 ko05321 Inflammatory bowel disease (IBD) 12/633 56/7206 0.00288549823661 ko04727 GABAergic synapse 19/633 110/7206 0.0035090687937 ko04020 Calcium signaling pathway 37/633 265/7206 0.00392486780731 ko00564 Glycerophospholipid metabolism 17/633 99/7206 0.00638969789304 ko04024 cAMP signaling pathway 38/633 279/7206 0.00659009038936 ko00562 Inositol phosphate metabolism 16/633 89/7206 0.00679718014889 ko04110 Cell cycle 4/633 145/7206 0.00684926815512 ko04630 Jak-STAT signaling pathway 21/633 132/7206 0.00738495676543 ko04919 Thyroid hormone signaling pathway 22/633 143/7206 0.0100833820863 ko04022 cGMP-PKG signaling pathway 30/633 216/7206 0.0101609572252 ko04964 Proximal tubule bicarbonate reclamation 7/633 29/7206 0.010987752575 ko03015 mRNA surveillance pathway 2/633 93/7206 0.0158485840973 ko04725 Cholinergic synapse 23/633 160/7206 0.0159613910278 ko00592 alpha-Linolenic acid metabolism 5/633 19/7206 0.0211860168912 ko04931 Insulin resistance 20/633 137/7206 0.0213589802033 ko04711 Circadian rhythm - fly 4/633 13/7206 0.0221797928455 ko04140 Autophagy - animal 23/633 164/7206 0.0242935357663 ko04930 Type II diabetes mellitus 10/633 54/7206 0.0244995692769 ko04921 Oxytocin signaling pathway 28/633 209/7206 0.0245495910026 ko04922 Glucagon signaling pathway 19/633 128/7206 0.0254301012087 ko05016 Huntington's disease 10/633 215/7206 0.027197683075 ko05033 Nicotine addiction 10/633 56/7206 0.0281227368715 ko04911 Insulin secretion 17/633 117/7206 0.0323700580663 ko04152 AMPK signaling pathway 22/633 161/7206 0.0338345311195 ko00965 Betalain biosynthesis 2/633 4/7206 0.0410099006008 ko00471 D-Glutamine and D-glutamate metabolism 2/633 4/7206 0.0410099006008 ko04713 Circadian entrainment 19/633 136/7206 0.044563590927 ko05131 Shigellosis 2/633 82/7206 0.0462184352612 ko04728 Dopaminergic synapse 24/633 185/7206 0.0478404099426