ko pathway ratio_in_study ratio_in_pop p_value ko03040 Spliceosome 43/261 145/7206 1.96584120274e-28 ko03030 DNA replication 21/261 38/7206 4.08626863111e-21 ko03015 mRNA surveillance pathway 21/261 93/7206 8.79138509437e-12 ko00240 Pyrimidine metabolism 22/261 110/7206 3.61153142571e-11 ko04110 Cell cycle 25/261 145/7206 4.83290165613e-11 ko03013 RNA transport 25/261 166/7206 9.64235915331e-10 ko00230 Purine metabolism 23/261 194/7206 4.41169256113e-07 ko03420 Nucleotide excision repair 11/261 46/7206 4.93279762307e-07 ko03020 RNA polymerase 9/261 29/7206 4.95704461301e-07 ko03430 Mismatch repair 8/261 22/7206 5.47552171884e-07 ko04080 Neuroactive ligand-receptor interaction 1/261 423/7206 2.96698635091e-06 ko04111 Cell cycle - yeast 14/261 90/7206 3.62101173801e-06 ko03008 Ribosome biogenesis in eukaryotes 13/261 79/7206 4.26251892784e-06 ko03410 Base excision repair 9/261 38/7206 6.05785759909e-06 ko03460 Fanconi anemia pathway 9/261 51/7206 7.48234210779e-05 ko04113 Meiosis - yeast 10/261 70/7206 0.000190367694352 ko04612 Antigen processing and presentation 10/261 77/7206 0.000421301412266 ko03050 Proteasome 8/261 54/7206 0.000651453222222 ko04020 Calcium signaling pathway 1/261 265/7206 0.00111792572281 ko05169 Epstein-Barr virus infection 17/261 206/7206 0.00169148203668 ko04144 Endocytosis 3/261 342/7206 0.00258943907486 ko04010 MAPK signaling pathway 4/261 321/7206 0.0139706184528 ko05166 HTLV-I infection 19/261 292/7206 0.0147921248452 ko04141 Protein processing in endoplasmic reticulum 1/261 184/7206 0.0151242686381 ko03450 Non-homologous end-joining 3/261 15/7206 0.0154706103494 ko04060 Cytokine-cytokine receptor interaction 1/261 191/7206 0.0159281284534 ko04910 Insulin signaling pathway 1/261 172/7206 0.0217968721784 ko04022 cGMP-PKG signaling pathway 2/261 216/7206 0.0250988129036 ko03018 RNA degradation 7/261 84/7206 0.0319878542686 ko05418 Fluid shear stress and atherosclerosis 12/261 173/7206 0.0348847837563 ko04261 Adrenergic signaling in cardiomyocytes 2/261 205/7206 0.0352220602067 ko04921 Oxytocin signaling pathway 2/261 209/7206 0.0358749633836 ko04218 Cellular senescence 12/261 177/7206 0.0373094860931 ko05222 Small cell lung cancer 7/261 89/7206 0.0418737912927 ko04724 Glutamatergic synapse 1/261 152/7206 0.0454208345198 ko04270 Vascular smooth muscle contraction 1/261 154/7206 0.0459122364132