ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	128/658	423/7206	6.89189668719e-38
ko04724	Glutamatergic synapse	71/658	152/7206	1.20072429645e-34
ko05033	Nicotine addiction	40/658	56/7206	8.94188425835e-30
ko04727	GABAergic synapse	51/658	110/7206	6.85043434244e-25
ko05032	Morphine addiction	49/658	110/7206	5.47773748563e-23
ko04723	Retrograde endocannabinoid signaling	60/658	175/7206	7.58524334863e-21
ko04713	Circadian entrainment	51/658	136/7206	7.98395823094e-20
ko04728	Dopaminergic synapse	60/658	185/7206	1.8089165519e-19
ko04744	Phototransduction	25/658	36/7206	1.53645423005e-18
ko04721	Synaptic vesicle cycle	32/658	80/7206	8.51026036156e-14
ko04725	Cholinergic synapse	47/658	160/7206	1.21939826228e-13
ko04024	cAMP signaling pathway	66/658	279/7206	1.30510327129e-13
ko04911	Insulin secretion	39/658	117/7206	1.79220527886e-13
ko04742	Taste transduction	26/658	61/7206	3.27735403995e-12
ko04726	Serotonergic synapse	40/658	137/7206	1.07734686104e-11
ko04020	Calcium signaling pathway	60/658	265/7206	1.91689741308e-11
ko04921	Oxytocin signaling pathway	50/658	209/7206	9.3015154142e-11
ko04740	Olfactory transduction	27/658	80/7206	7.39434967608e-10
ko04970	Salivary secretion	29/658	95/7206	2.51689172958e-09
ko05031	Amphetamine addiction	28/658	91/7206	3.89841951821e-09
ko04261	Adrenergic signaling in cardiomyocytes	45/658	205/7206	1.73418287949e-08
ko05030	Cocaine addiction	23/658	73/7206	5.9354649373e-08
ko04720	Long-term potentiation	27/658	99/7206	1.25288394667e-07
ko04972	Pancreatic secretion	28/658	111/7206	4.35084966021e-07
ko05203	Viral carcinogenesis	6/658	277/7206	3.28474708723e-06
ko04971	Gastric acid secretion	24/658	98/7206	5.0840710797e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	20/658	74/7206	6.31115059578e-06
ko03040	Spliceosome	1/658	145/7206	2.67389311033e-05
ko05164	Influenza A	2/658	167/7206	2.99168909787e-05
ko04120	Ubiquitin mediated proteolysis	1/658	138/7206	3.83548891225e-05
ko04730	Long-term depression	19/658	78/7206	5.27288981247e-05
ko04260	Cardiac muscle contraction	22/658	98/7206	5.35371699514e-05
ko04022	cGMP-PKG signaling pathway	38/658	216/7206	6.15303057529e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/658	79/7206	6.36216365981e-05
ko04010	MAPK signaling pathway	50/658	321/7206	0.0001426671774
ko04964	Proximal tubule bicarbonate reclamation	10/658	29/7206	0.000151205285531
ko04110	Cell cycle	2/658	145/7206	0.000199371620718
ko05162	Measles	1/658	120/7206	0.000296571231026
ko04925	Aldosterone synthesis and secretion	21/658	105/7206	0.000475172919177
ko05322	Systemic lupus erythematosus	3/658	151/7206	0.000535727779647
ko04072	Phospholipase D signaling pathway	33/658	197/7206	0.000588279378719
ko05169	Epstein-Barr virus infection	6/658	206/7206	0.000779470044027
ko03013	RNA transport	4/658	166/7206	0.000900129808321
ko04932	Non-alcoholic fatty liver disease (NAFLD)	5/658	182/7206	0.000979464927028
ko04976	Bile secretion	17/658	80/7206	0.00118066903678
ko05414	Dilated cardiomyopathy	21/658	112/7206	0.00130911541599
ko05205	Proteoglycans in cancer	11/658	271/7206	0.00171304484867
ko04514	Cell adhesion molecules (CAMs)	23/658	130/7206	0.00178040310334
ko04060	Cytokine-cytokine receptor interaction	6/658	191/7206	0.00198415252141
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/658	59/7206	0.00212586734375
ko04150	mTOR signaling pathway	6/658	184/7206	0.00266123468308
ko05168	Herpes simplex infection	6/658	182/7206	0.00371846964312
ko05215	Prostate cancer	2/658	111/7206	0.0039625540152
ko05034	Alcoholism	35/658	238/7206	0.00404841712645
ko04350	TGF-beta signaling pathway	2/658	103/7206	0.00539284209345
ko04924	Renin secretion	16/658	86/7206	0.00681390369516
ko04621	NOD-like receptor signaling pathway	5/658	157/7206	0.00701744743224
ko04540	Gap junction	21/658	128/7206	0.00764289712968
ko04141	Protein processing in endoplasmic reticulum	7/658	184/7206	0.008866231817
ko05130	Pathogenic Escherichia coli infection	1/658	77/7206	0.00893785923877
ko04612	Antigen processing and presentation	1/658	77/7206	0.00893785923877
ko04550	Signaling pathways regulating pluripotency of stem cells	6/658	165/7206	0.00905142704331
ko04014	Ras signaling pathway	38/658	279/7206	0.0107637165289
ko04510	Focal adhesion	11/658	240/7206	0.0115738091863
ko04062	Chemokine signaling pathway	29/658	201/7206	0.0124104903366
ko05410	Hypertrophic cardiomyopathy (HCM)	17/658	100/7206	0.0126073221945
ko05166	HTLV-I infection	15/658	292/7206	0.0126294859211
ko04214	Apoptosis - fly	1/658	72/7206	0.0130736247734
ko00310	Lysine degradation	1/658	73/7206	0.0130898060822
ko05161	Hepatitis B	7/658	173/7206	0.0155422607681
ko04146	Peroxisome	2/658	89/7206	0.0156874721091
ko04070	Phosphatidylinositol signaling system	18/658	112/7206	0.0187501486608
ko04745	Phototransduction - fly	8/658	38/7206	0.0192824378239
ko04915	Estrogen signaling pathway	20/658	131/7206	0.0205040171439
ko04142	Lysosome	6/658	151/7206	0.0218642537223
ko05218	Melanoma	2/658	85/7206	0.0222561520415
ko04931	Insulin resistance	5/658	137/7206	0.0233049197407
ko04750	Inflammatory mediator regulation of TRP channels	19/658	122/7206	0.024574284339
ko04210	Apoptosis	8/658	180/7206	0.0250988907597
ko04978	Mineral absorption	8/658	40/7206	0.0258194887547
ko00561	Glycerolipid metabolism	1/658	63/7206	0.0277971745693
ko04640	Hematopoietic cell lineage	1/658	64/7206	0.0278154468349
ko04930	Type II diabetes mellitus	10/658	54/7206	0.0281297288527
ko04960	Aldosterone-regulated sodium reabsorption	8/658	41/7206	0.0296068938047
ko04630	Jak-STAT signaling pathway	5/658	132/7206	0.0312322989327
ko05224	Breast cancer	8/658	174/7206	0.0326219887284
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/658	14/7206	0.0328439957401
ko03018	RNA degradation	2/658	84/7206	0.032966899546
ko04666	Fc gamma R-mediated phagocytosis	18/658	122/7206	0.0380149535562
ko05202	Transcriptional misregulation in cancer	9/658	188/7206	0.0388299121797
ko00562	Inositol phosphate metabolism	14/658	89/7206	0.0395810178805
ko01212	Fatty acid metabolism	1/658	60/7206	0.0405680315325
ko00330	Arginine and proline metabolism	1/658	61/7206	0.0410958567738
ko05145	Toxoplasmosis	5/658	126/7206	0.0414377664385
ko04330	Notch signaling pathway	1/658	62/7206	0.0419569605816
ko05110	Vibrio cholerae infection	11/658	63/7206	0.0431504979564
ko04610	Complement and coagulation cascades	2/658	79/7206	0.0459597707698
ko04064	NF-kappa B signaling pathway	3/658	96/7206	0.046658505805
ko05231	Choline metabolism in cancer	19/658	134/7206	0.0481515612843