ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	161/825	423/7206	1.65055933812e-49
ko05033	Nicotine addiction	44/825	56/7206	1.97085118763e-31
ko04724	Glutamatergic synapse	73/825	152/7206	5.65782343139e-30
ko04721	Synaptic vesicle cycle	47/825	80/7206	1.36655546801e-24
ko05032	Morphine addiction	54/825	110/7206	5.58175918886e-23
ko04727	GABAergic synapse	53/825	110/7206	4.35574931413e-22
ko04728	Dopaminergic synapse	65/825	185/7206	7.66599230381e-18
ko04723	Retrograde endocannabinoid signaling	62/825	175/7206	2.86671937104e-17
ko04713	Circadian entrainment	53/825	136/7206	5.50205872576e-17
ko04725	Cholinergic synapse	55/825	160/7206	8.60175384001e-15
ko04726	Serotonergic synapse	48/825	137/7206	2.04243909357e-13
ko04024	cAMP signaling pathway	75/825	279/7206	3.51904125316e-13
ko04742	Taste transduction	28/825	61/7206	1.33331687097e-11
ko04911	Insulin secretion	39/825	117/7206	2.17282359217e-10
ko04921	Oxytocin signaling pathway	54/825	209/7206	6.23808894368e-09
ko05031	Amphetamine addiction	31/825	91/7206	8.76773502628e-09
ko04744	Phototransduction	18/825	36/7206	1.16491868353e-08
ko05030	Cocaine addiction	26/825	73/7206	4.96596309536e-08
ko04020	Calcium signaling pathway	61/825	265/7206	5.80317696971e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	26/825	74/7206	6.83816772558e-08
ko04966	Collecting duct acid secretion	14/825	26/7206	1.53704672623e-07
ko05203	Viral carcinogenesis	8/825	277/7206	2.17830402966e-07
ko04720	Long-term potentiation	30/825	99/7206	2.97795252959e-07
ko04261	Adrenergic signaling in cardiomyocytes	49/825	205/7206	3.13082167049e-07
ko04010	MAPK signaling pathway	68/825	321/7206	3.37708159221e-07
ko04060	Cytokine-cytokine receptor interaction	3/825	191/7206	3.71588593003e-07
ko05164	Influenza A	2/825	167/7206	4.79971975271e-07
ko03040	Spliceosome	1/825	145/7206	5.49341307609e-07
ko05168	Herpes simplex infection	4/825	182/7206	5.0463083359e-06
ko04730	Long-term depression	22/825	78/7206	3.95074521747e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/825	79/7206	4.89582330196e-05
ko05169	Epstein-Barr virus infection	7/825	206/7206	5.01592335961e-05
ko04514	Cell adhesion molecules (CAMs)	31/825	130/7206	6.46063983026e-05
ko03013	RNA transport	5/825	166/7206	0.000111160977186
ko04120	Ubiquitin mediated proteolysis	3/825	138/7206	0.000112503620683
ko05162	Measles	2/825	120/7206	0.000118070655097
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/825	182/7206	0.000127501848952
ko04970	Salivary secretion	24/825	95/7206	0.00013310814684
ko05110	Vibrio cholerae infection	18/825	63/7206	0.000163902362743
ko04260	Cardiac muscle contraction	24/825	98/7206	0.000293337868105
ko04621	NOD-like receptor signaling pathway	5/825	157/7206	0.00031688433949
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/825	14/7206	0.000417244263778
ko05205	Proteoglycans in cancer	14/825	271/7206	0.000422813738015
ko05322	Systemic lupus erythematosus	5/825	151/7206	0.000645490346144
ko04360	Axon guidance	44/825	233/7206	0.000731279223564
ko04350	TGF-beta signaling pathway	2/825	103/7206	0.000810211254269
ko04141	Protein processing in endoplasmic reticulum	8/825	184/7206	0.000946460974464
ko03008	Ribosome biogenesis in eukaryotes	1/825	79/7206	0.00115571053824
ko05166	HTLV-I infection	17/825	292/7206	0.00132310045841
ko04924	Renin secretion	20/825	86/7206	0.0017055112827
ko04612	Antigen processing and presentation	1/825	77/7206	0.00174332727558
ko04740	Olfactory transduction	19/825	80/7206	0.00202411476472
ko04214	Apoptosis - fly	1/825	72/7206	0.00253805765255
ko00310	Lysine degradation	1/825	73/7206	0.00255709994313
ko04540	Gap junction	26/825	128/7206	0.00300445662696
ko04110	Cell cycle	6/825	145/7206	0.00336268994674
ko04971	Gastric acid secretion	21/825	98/7206	0.0036901084916
ko04014	Ras signaling pathway	48/825	279/7206	0.00379358244757
ko05146	Amoebiasis	3/825	99/7206	0.00397784692796
ko05414	Dilated cardiomyopathy	23/825	112/7206	0.00428203229973
ko05120	Epithelial cell signaling in Helicobacter pylori infection	20/825	92/7206	0.0043251494397
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	6/825	15/7206	0.00444384501948
ko04925	Aldosterone synthesis and secretion	22/825	105/7206	0.00473406664209
ko03018	RNA degradation	2/825	84/7206	0.00499511729021
ko04022	cGMP-PKG signaling pathway	38/825	216/7206	0.00637068857882
ko05161	Hepatitis B	9/825	173/7206	0.00733398131968
ko04972	Pancreatic secretion	22/825	111/7206	0.00969328996664
ko05140	Leishmaniasis	2/825	75/7206	0.0101363119668
ko05410	Hypertrophic cardiomyopathy (HCM)	20/825	100/7206	0.0108212816028
ko04146	Peroxisome	3/825	89/7206	0.011219213614
ko01200	Carbon metabolism	6/825	128/7206	0.0113091580937
ko04964	Proximal tubule bicarbonate reclamation	8/825	29/7206	0.0136329262416
ko05418	Fluid shear stress and atherosclerosis	10/825	173/7206	0.015171375656
ko05215	Prostate cancer	5/825	111/7206	0.0158292290525
ko05323	Rheumatoid arthritis	18/825	89/7206	0.0171934302707
ko00280	Valine, leucine and isoleucine degradation	1/825	54/7206	0.0177171182837
ko00480	Glutathione metabolism	1/825	55/7206	0.0177822398743
ko04668	TNF signaling pathway	6/825	120/7206	0.0204904567068
ko05016	Huntington's disease	14/825	215/7206	0.021667466505
ko00240	Pyrimidine metabolism	5/825	110/7206	0.0221007515233
ko04064	NF-kappa B signaling pathway	4/825	96/7206	0.022402461011
ko04145	Phagosome	28/825	162/7206	0.0240181471897
ko04140	Autophagy - animal	10/825	164/7206	0.0255078826694
ko04630	Jak-STAT signaling pathway	7/825	132/7206	0.0259973032534
ko04640	Hematopoietic cell lineage	2/825	64/7206	0.0295595969644
ko05034	Alcoholism	38/825	238/7206	0.0296699971229
ko05145	Toxoplasmosis	7/825	126/7206	0.0336934139143
ko04915	Estrogen signaling pathway	23/825	131/7206	0.036365681764
ko05219	Bladder cancer	1/825	48/7206	0.0382800864053
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/825	59/7206	0.0392469565098
ko04072	Phospholipase D signaling pathway	32/825	197/7206	0.0402592508959
ko00512	Mucin type O-glycan biosynthesis	7/825	29/7206	0.0412143040821
ko04657	IL-17 signaling pathway	4/825	87/7206	0.0413220644834
ko05133	Pertussis	4/825	87/7206	0.0413220644834
ko00330	Arginine and proline metabolism	2/825	61/7206	0.0420363641791
ko00561	Glycerolipid metabolism	2/825	63/7206	0.0434432605971
ko01524	Platinum drug resistance	3/825	76/7206	0.0436176518932