ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	155/886	423/7206	6.53703480021e-41
ko04724	Glutamatergic synapse	80/886	152/7206	3.37468425957e-34
ko05033	Nicotine addiction	45/886	56/7206	1.56353185138e-31
ko05032	Morphine addiction	60/886	110/7206	5.93753458092e-27
ko04727	GABAergic synapse	58/886	110/7206	4.59256226516e-25
ko04728	Dopaminergic synapse	76/886	185/7206	1.16783518285e-23
ko04713	Circadian entrainment	63/886	136/7206	3.76009706873e-23
ko04723	Retrograde endocannabinoid signaling	70/886	175/7206	4.59879862236e-21
ko04725	Cholinergic synapse	64/886	160/7206	2.42909891025e-19
ko04721	Synaptic vesicle cycle	43/886	80/7206	2.70734109596e-19
ko04024	cAMP signaling pathway	86/886	279/7206	4.51940281104e-17
ko04744	Phototransduction	25/886	36/7206	2.02729929408e-15
ko04742	Taste transduction	31/886	61/7206	2.22904207555e-13
ko04911	Insulin secretion	45/886	117/7206	3.25711473697e-13
ko04726	Serotonergic synapse	49/886	137/7206	7.24843785384e-13
ko04921	Oxytocin signaling pathway	63/886	209/7206	3.52297472101e-12
ko04020	Calcium signaling pathway	73/886	265/7206	1.05762550063e-11
ko04261	Adrenergic signaling in cardiomyocytes	60/886	205/7206	3.7416989719e-11
ko04720	Long-term potentiation	37/886	99/7206	1.14988366002e-10
ko05031	Amphetamine addiction	35/886	91/7206	1.45528207816e-10
ko03040	Spliceosome	1/886	145/7206	1.4410798866e-07
ko04970	Salivary secretion	30/886	95/7206	5.22104456202e-07
ko04925	Aldosterone synthesis and secretion	32/886	105/7206	5.39744812639e-07
ko05030	Cocaine addiction	25/886	73/7206	8.53737589794e-07
ko04740	Olfactory transduction	26/886	80/7206	1.62223675663e-06
ko05203	Viral carcinogenesis	11/886	277/7206	2.21488792132e-06
ko04060	Cytokine-cytokine receptor interaction	5/886	191/7206	2.96193377567e-06
ko04010	MAPK signaling pathway	68/886	321/7206	4.76762185846e-06
ko05164	Influenza A	4/886	167/7206	6.79720657803e-06
ko04730	Long-term depression	24/886	78/7206	1.1763310063e-05
ko04971	Gastric acid secretion	28/886	98/7206	1.33442678217e-05
ko05168	Herpes simplex infection	6/886	182/7206	2.95662543783e-05
ko04022	cGMP-PKG signaling pathway	48/886	216/7206	3.23111453374e-05
ko04260	Cardiac muscle contraction	27/886	98/7206	3.46193227395e-05
ko04514	Cell adhesion molecules (CAMs)	33/886	130/7206	3.50041479075e-05
ko03013	RNA transport	5/886	166/7206	3.62290931642e-05
ko05322	Systemic lupus erythematosus	4/886	151/7206	4.37144628361e-05
ko04072	Phospholipase D signaling pathway	44/886	197/7206	6.03760670592e-05
ko04745	Phototransduction - fly	14/886	38/7206	9.08706255858e-05
ko04621	NOD-like receptor signaling pathway	5/886	157/7206	0.000106877082055
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/886	79/7206	0.000173358291394
ko04972	Pancreatic secretion	28/886	111/7206	0.000187199364846
ko04120	Ubiquitin mediated proteolysis	4/886	138/7206	0.000188284173843
ko04070	Phosphatidylinositol signaling system	28/886	112/7206	0.000203835470266
ko05014	Amyotrophic lateral sclerosis (ALS)	21/886	74/7206	0.000208713945276
ko04141	Protein processing in endoplasmic reticulum	8/886	184/7206	0.000358426669282
ko04966	Collecting duct acid secretion	10/886	26/7206	0.000623350566591
ko04612	Antigen processing and presentation	1/886	77/7206	0.000739493689411
ko04610	Complement and coagulation cascades	1/886	79/7206	0.000769680140568
ko03008	Ribosome biogenesis in eukaryotes	1/886	79/7206	0.000769680140568
ko05162	Measles	4/886	120/7206	0.00106966601745
ko05414	Dilated cardiomyopathy	26/886	112/7206	0.00117132214927
ko04110	Cell cycle	6/886	145/7206	0.00122634171875
ko05161	Hepatitis B	9/886	173/7206	0.00219816443407
ko05169	Epstein-Barr virus infection	12/886	206/7206	0.00246826761782
ko05166	HTLV-I infection	20/886	292/7206	0.00259094537433
ko04064	NF-kappa B signaling pathway	3/886	96/7206	0.00268496160706
ko04915	Estrogen signaling pathway	28/886	131/7206	0.00285991067303
ko04360	Axon guidance	44/886	233/7206	0.00311750419194
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/886	14/7206	0.00425097844762
ko04750	Inflammatory mediator regulation of TRP channels	26/886	122/7206	0.00483461057914
ko04014	Ras signaling pathway	50/886	279/7206	0.00513781082322
ko04930	Type II diabetes mellitus	14/886	54/7206	0.00545411496753
ko04964	Proximal tubule bicarbonate reclamation	9/886	29/7206	0.00626184630132
ko00310	Lysine degradation	2/886	73/7206	0.00681706261629
ko05140	Leishmaniasis	2/886	75/7206	0.00696310761667
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/886	182/7206	0.00806588939156
ko00562	Inositol phosphate metabolism	20/886	89/7206	0.00820419269584
ko04540	Gap junction	26/886	128/7206	0.00916896018258
ko05110	Vibrio cholerae infection	15/886	63/7206	0.0105188112041
ko05205	Proteoglycans in cancer	20/886	271/7206	0.0106149216859
ko04924	Renin secretion	19/886	86/7206	0.0117557123413
ko00480	Glutathione metabolism	1/886	55/7206	0.0118032168697
ko05410	Hypertrophic cardiomyopathy (HCM)	21/886	100/7206	0.0130221730271
ko04371	Apelin signaling pathway	33/886	177/7206	0.0142678106279
ko05217	Basal cell carcinoma	2/886	68/7206	0.0143210027414
ko05034	Alcoholism	42/886	238/7206	0.0154722893106
ko04626	Plant-pathogen interaction	6/886	18/7206	0.0170724328125
ko04640	Hematopoietic cell lineage	2/886	64/7206	0.0203089784575
ko04510	Focal adhesion	18/886	240/7206	0.0209894207013
ko04062	Chemokine signaling pathway	36/886	201/7206	0.0213970093693
ko04146	Peroxisome	4/886	89/7206	0.0217008387319
ko04550	Signaling pathways regulating pluripotency of stem cells	11/886	165/7206	0.0225266773847
ko05219	Bladder cancer	1/886	48/7206	0.0254611613942
ko05016	Huntington's disease	16/886	215/7206	0.0264365268153
ko05215	Prostate cancer	6/886	111/7206	0.0273957986485
ko00330	Arginine and proline metabolism	2/886	61/7206	0.0291684536445
ko04140	Autophagy - animal	11/886	164/7206	0.0293739814221
ko03018	RNA degradation	4/886	84/7206	0.0295656492062
ko04330	Notch signaling pathway	2/886	62/7206	0.0298471181201
ko04214	Apoptosis - fly	3/886	72/7206	0.0299164648241
ko04657	IL-17 signaling pathway	4/886	87/7206	0.0306336093456
ko04630	Jak-STAT signaling pathway	8/886	132/7206	0.0309590393121
ko04973	Carbohydrate digestion and absorption	10/886	42/7206	0.0318948704798
ko05231	Choline metabolism in cancer	25/886	134/7206	0.0323964482869
ko03022	Basal transcription factors	1/886	44/7206	0.0371924200278
ko00071	Fatty acid degradation	1/886	45/7206	0.0375939862704
ko04210	Apoptosis	13/886	180/7206	0.0377029253316
ko03420	Nucleotide excision repair	1/886	46/7206	0.0385914091035
ko04976	Bile secretion	16/886	80/7206	0.0402572142848
ko05321	Inflammatory bowel disease (IBD)	2/886	56/7206	0.0410589408926
ko03320	PPAR signaling pathway	3/886	69/7206	0.0416708059097
ko05206	MicroRNAs in cancer	13/886	177/7206	0.0477356619668
ko04350	TGF-beta signaling pathway	6/886	103/7206	0.0478660102014