ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	68/748	152/7206	2.90950362864e-28
ko04080	Neuroactive ligand-receptor interaction	121/748	423/7206	1.69117168786e-27
ko05033	Nicotine addiction	38/748	56/7206	5.97477702061e-25
ko04727	GABAergic synapse	47/748	110/7206	8.15688504655e-19
ko05032	Morphine addiction	47/748	110/7206	8.15688504655e-19
ko04728	Dopaminergic synapse	60/748	185/7206	1.01297195873e-16
ko04024	cAMP signaling pathway	77/748	279/7206	1.29453287511e-16
ko04713	Circadian entrainment	49/748	136/7206	6.39675194204e-16
ko04725	Cholinergic synapse	53/748	160/7206	2.48093748123e-15
ko04723	Retrograde endocannabinoid signaling	55/748	175/7206	9.43119594632e-15
ko04721	Synaptic vesicle cycle	32/748	80/7206	2.97743635793e-12
ko04911	Insulin secretion	39/748	117/7206	1.07208774451e-11
ko04360	Axon guidance	59/748	233/7206	3.54009889153e-11
ko04726	Serotonergic synapse	41/748	137/7206	1.48609291505e-10
ko04744	Phototransduction	18/748	36/7206	2.39746020621e-09
ko04742	Taste transduction	23/748	61/7206	1.37302448862e-08
ko04261	Adrenergic signaling in cardiomyocytes	47/748	205/7206	1.35690450278e-07
ko04020	Calcium signaling pathway	56/748	265/7206	1.55154111984e-07
ko05030	Cocaine addiction	23/748	73/7206	6.16633528328e-07
ko04921	Oxytocin signaling pathway	46/748	209/7206	6.95231803769e-07
ko04514	Cell adhesion molecules (CAMs)	33/748	130/7206	7.1417306971e-07
ko05031	Amphetamine addiction	26/748	91/7206	9.73036674244e-07
ko04970	Salivary secretion	26/748	95/7206	2.38837219882e-06
ko05203	Viral carcinogenesis	8/748	277/7206	2.78362488635e-06
ko03040	Spliceosome	1/748	145/7206	3.11986744861e-06
ko04010	MAPK signaling pathway	60/748	321/7206	5.21732335954e-06
ko04720	Long-term potentiation	26/748	99/7206	5.50701747527e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	21/748	74/7206	1.20382388337e-05
ko04022	cGMP-PKG signaling pathway	43/748	216/7206	2.10006900677e-05
ko04972	Pancreatic secretion	27/748	111/7206	2.17631180547e-05
ko03013	RNA transport	3/748	166/7206	2.65765100439e-05
ko05168	Herpes simplex infection	5/748	182/7206	0.000173974947012
ko05164	Influenza A	5/748	167/7206	0.000469179233444
ko04730	Long-term depression	19/748	78/7206	0.000475892454476
ko05322	Systemic lupus erythematosus	4/748	151/7206	0.000607867080859
ko04924	Renin secretion	19/748	86/7206	0.00114306890976
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/748	79/7206	0.00114548947169
ko04260	Cardiac muscle contraction	21/748	98/7206	0.0011594358988
ko04971	Gastric acid secretion	21/748	98/7206	0.0011594358988
ko04072	Phospholipase D signaling pathway	35/748	197/7206	0.00127056662529
ko04141	Protein processing in endoplasmic reticulum	7/748	184/7206	0.00136169620222
ko04120	Ubiquitin mediated proteolysis	4/748	138/7206	0.0016701855917
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/748	14/7206	0.00177005405563
ko04964	Proximal tubule bicarbonate reclamation	9/748	29/7206	0.00196754181894
ko04014	Ras signaling pathway	45/748	279/7206	0.00250185318099
ko04610	Complement and coagulation cascades	1/748	79/7206	0.00267634040574
ko05205	Proteoglycans in cancer	14/748	271/7206	0.00302913782169
ko04925	Aldosterone synthesis and secretion	21/748	105/7206	0.00308739326361
ko04071	Sphingolipid signaling pathway	29/748	162/7206	0.00369945409071
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/748	59/7206	0.0038383660595
ko00240	Pyrimidine metabolism	3/748	110/7206	0.004167958673
ko04978	Mineral absorption	10/748	40/7206	0.00643269788968
ko05210	Colorectal cancer	17/748	86/7206	0.00731196086013
ko04973	Carbohydrate digestion and absorption	10/748	42/7206	0.00923618242892
ko03018	RNA degradation	2/748	84/7206	0.0106341717241
ko04621	NOD-like receptor signaling pathway	7/748	157/7206	0.0112935493878
ko04371	Apelin signaling pathway	29/748	177/7206	0.0120298055118
ko04640	Hematopoietic cell lineage	1/748	64/7206	0.0125225591842
ko04915	Estrogen signaling pathway	23/748	131/7206	0.0128356567987
ko04966	Collecting duct acid secretion	7/748	26/7206	0.014244322461
ko05169	Epstein-Barr virus infection	11/748	206/7206	0.0143641455458
ko04060	Cytokine-cytokine receptor interaction	10/748	191/7206	0.0156685049269
ko04137	Mitophagy - animal	2/748	82/7206	0.0158720865462
ko04070	Phosphatidylinositol signaling system	20/748	112/7206	0.0175862686476
ko00330	Arginine and proline metabolism	1/748	61/7206	0.018499922248
ko05140	Leishmaniasis	2/748	75/7206	0.0214612345424
ko04612	Antigen processing and presentation	2/748	77/7206	0.021995455087
ko04146	Peroxisome	3/748	89/7206	0.0227110113915
ko04930	Type II diabetes mellitus	11/748	54/7206	0.0235282667051
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/748	182/7206	0.0262226649829
ko04110	Cell cycle	7/748	145/7206	0.0265727360676
ko04974	Protein digestion and absorption	17/748	96/7206	0.0266772144037
ko05414	Dilated cardiomyopathy	19/748	112/7206	0.027961449871
ko01200	Carbon metabolism	6/748	128/7206	0.0282127393466
ko04214	Apoptosis - fly	2/748	72/7206	0.0307080009014
ko04960	Aldosterone-regulated sodium reabsorption	9/748	41/7206	0.0333075838499
ko04217	Necroptosis	10/748	178/7206	0.0337679952194
ko04015	Rap1 signaling pathway	40/748	278/7206	0.0344243531712
ko00590	Arachidonic acid metabolism	1/748	52/7206	0.0391282105204
ko04512	ECM-receptor interaction	14/748	79/7206	0.039970817566
ko00480	Glutathione metabolism	1/748	55/7206	0.0412383850227
ko04976	Bile secretion	14/748	80/7206	0.0424036483927
ko03320	PPAR signaling pathway	2/748	69/7206	0.044146920733
ko05162	Measles	6/748	120/7206	0.0495456382884