ko pathway ratio_in_study ratio_in_pop p_value ko04146 Peroxisome 14/177 89/7206 2.66558499168e-08 ko00071 Fatty acid degradation 10/177 45/7206 9.39911517667e-08 ko00120 Primary bile acid biosynthesis 6/177 20/7206 5.87464380645e-06 ko00350 Tyrosine metabolism 7/177 33/7206 1.19286712986e-05 ko03320 PPAR signaling pathway 9/177 69/7206 4.23418959405e-05 ko00950 Isoquinoline alkaloid biosynthesis 4/177 10/7206 6.58271740789e-05 ko00592 alpha-Linolenic acid metabolism 5/177 19/7206 7.42834001197e-05 ko01212 Fatty acid metabolism 8/177 60/7206 9.72519726993e-05 ko00330 Arginine and proline metabolism 8/177 61/7206 0.00010961623347 ko00982 Drug metabolism - cytochrome P450 6/177 37/7206 0.000249033899144 ko00983 Drug metabolism - other enzymes 6/177 42/7206 0.000507618295051 ko00360 Phenylalanine metabolism 4/177 17/7206 0.000651866191523 ko04270 Vascular smooth muscle contraction 11/177 154/7206 0.00137649862883 ko00590 Arachidonic acid metabolism 6/177 52/7206 0.00160855813526 ko01040 Biosynthesis of unsaturated fatty acids 4/177 25/7206 0.00297220179694 ko00140 Steroid hormone biosynthesis 5/177 41/7206 0.00309287830577 ko00830 Retinol metabolism 5/177 42/7206 0.00344223776668 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 2/177 4/7206 0.00348450605369 ko00710 Carbon fixation in photosynthetic organisms 4/177 27/7206 0.00396900990247 ko01200 Carbon metabolism 9/177 128/7206 0.00413091632498 ko00380 Tryptophan metabolism 5/177 50/7206 0.00732466607772 ko00362 Benzoate degradation 2/177 6/7206 0.00843275761944 ko04610 Complement and coagulation cascades 6/177 79/7206 0.0127605757336 ko00220 Arginine biosynthesis 3/177 24/7206 0.0201849374254 ko04710 Circadian rhythm 4/177 43/7206 0.0206102764174 ko05144 Malaria 4/177 45/7206 0.0239648225953 ko00040 Pentose and glucuronate interconversions 3/177 26/7206 0.0250216040284 ko05204 Chemical carcinogenesis 4/177 48/7206 0.029584179708 ko00260 Glycine, serine and threonine metabolism 4/177 48/7206 0.029584179708 ko00190 Oxidative phosphorylation 7/177 127/7206 0.0364764088368 ko04020 Calcium signaling pathway 12/177 265/7206 0.0392992388559 ko00280 Valine, leucine and isoleucine degradation 4/177 54/7206 0.042984634489 ko04360 Axon guidance 1/177 233/7206 0.0476835348202 ko05321 Inflammatory bowel disease (IBD) 4/177 56/7206 0.0480977544209 ko04933 AGE-RAGE signaling pathway in diabetic complications 7/177 135/7206 0.0481312265973 ko00760 Nicotinate and nicotinamide metabolism 3/177 34/7206 0.0499845137748