ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	142/792	423/7206	3.14210445841e-38
ko04724	Glutamatergic synapse	73/792	152/7206	3.73347821624e-31
ko05033	Nicotine addiction	39/792	56/7206	2.65923127965e-25
ko04713	Circadian entrainment	58/792	136/7206	1.17233701093e-21
ko05032	Morphine addiction	51/792	110/7206	3.72539513039e-21
ko04727	GABAergic synapse	49/792	110/7206	1.92379286624e-19
ko04723	Retrograde endocannabinoid signaling	63/792	175/7206	7.56594836015e-19
ko04024	cAMP signaling pathway	80/792	279/7206	8.22820890583e-17
ko04728	Dopaminergic synapse	62/792	185/7206	8.43957102425e-17
ko04020	Calcium signaling pathway	77/792	265/7206	1.43448201687e-16
ko04911	Insulin secretion	47/792	117/7206	1.65912581735e-16
ko04725	Cholinergic synapse	56/792	160/7206	3.11581483165e-16
ko04720	Long-term potentiation	39/792	99/7206	1.41611591109e-13
ko04726	Serotonergic synapse	47/792	137/7206	1.94179748003e-13
ko04921	Oxytocin signaling pathway	60/792	209/7206	7.04487821883e-13
ko05031	Amphetamine addiction	35/792	91/7206	5.88029089436e-12
ko04261	Adrenergic signaling in cardiomyocytes	54/792	205/7206	4.09315699849e-10
ko04742	Taste transduction	25/792	61/7206	1.3470620093e-09
ko04925	Aldosterone synthesis and secretion	33/792	105/7206	1.02295455669e-08
ko04022	cGMP-PKG signaling pathway	52/792	216/7206	2.67013905681e-08
ko04010	MAPK signaling pathway	67/792	321/7206	1.25456924286e-07
ko04970	Salivary secretion	29/792	95/7206	1.63788731913e-07
ko04972	Pancreatic secretion	32/792	111/7206	1.66581923255e-07
ko04072	Phospholipase D signaling pathway	47/792	197/7206	1.77487742553e-07
ko04721	Synaptic vesicle cycle	26/792	80/7206	1.79190060819e-07
ko04730	Long-term depression	25/792	78/7206	4.17016158274e-07
ko04750	Inflammatory mediator regulation of TRP channels	33/792	122/7206	5.48963348014e-07
ko04070	Phosphatidylinositol signaling system	31/792	112/7206	7.00566603338e-07
ko04971	Gastric acid secretion	28/792	98/7206	1.20476458846e-06
ko03040	Spliceosome	1/792	145/7206	1.30956474514e-06
ko05030	Cocaine addiction	22/792	73/7206	6.45104207415e-06
ko04514	Cell adhesion molecules (CAMs)	32/792	130/7206	1.14259557064e-05
ko04710	Circadian rhythm	15/792	43/7206	2.83361718649e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	21/792	74/7206	2.8928103243e-05
ko04930	Type II diabetes mellitus	17/792	54/7206	3.86920763846e-05
ko05322	Systemic lupus erythematosus	3/792	151/7206	5.52520069595e-05
ko03013	RNA transport	4/792	166/7206	7.18685567436e-05
ko04745	Phototransduction - fly	13/792	38/7206	0.000121725616644
ko04540	Gap junction	29/792	128/7206	0.000143721376767
ko04918	Thyroid hormone synthesis	22/792	86/7206	0.000148214229366
ko04360	Axon guidance	44/792	233/7206	0.000261694105499
ko04270	Vascular smooth muscle contraction	32/792	154/7206	0.000347864250812
ko04260	Cardiac muscle contraction	23/792	98/7206	0.000435479434288
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/792	59/7206	0.000449044253423
ko04014	Ras signaling pathway	49/792	279/7206	0.000820437505769
ko04915	Estrogen signaling pathway	27/792	131/7206	0.00103780176471
ko04960	Aldosterone-regulated sodium reabsorption	12/792	41/7206	0.00110083829596
ko04711	Circadian rhythm - fly	6/792	13/7206	0.00150201973592
ko05203	Viral carcinogenesis	15/792	277/7206	0.0015981936064
ko03008	Ribosome biogenesis in eukaryotes	1/792	79/7206	0.00175646539283
ko04110	Cell cycle	5/792	145/7206	0.00176370918008
ko04141	Protein processing in endoplasmic reticulum	8/792	184/7206	0.00178470348937
ko05231	Choline metabolism in cancer	27/792	134/7206	0.00182467136242
ko04912	GnRH signaling pathway	25/792	122/7206	0.0018604817142
ko04371	Apelin signaling pathway	33/792	177/7206	0.00212929440534
ko05168	Herpes simplex infection	8/792	182/7206	0.00244310432093
ko04924	Renin secretion	19/792	86/7206	0.00259428409654
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/792	79/7206	0.00293517328642
ko00240	Pyrimidine metabolism	3/792	110/7206	0.00297468647271
ko04740	Olfactory transduction	18/792	80/7206	0.00313500879523
ko05414	Dilated cardiomyopathy	23/792	112/7206	0.00321843873348
ko00562	Inositol phosphate metabolism	19/792	89/7206	0.00534240991427
ko04060	Cytokine-cytokine receptor interaction	10/792	191/7206	0.00685550287993
ko04071	Sphingolipid signaling pathway	29/792	162/7206	0.00723791605852
ko05164	Influenza A	8/792	167/7206	0.00797364194269
ko04012	ErbB signaling pathway	21/792	109/7206	0.00849144457375
ko04922	Glucagon signaling pathway	24/792	128/7206	0.00933884242878
ko04964	Proximal tubule bicarbonate reclamation	8/792	29/7206	0.0107635215556
ko00330	Arginine and proline metabolism	1/792	61/7206	0.012300470094
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/792	14/7206	0.0135828992877
ko04621	NOD-like receptor signaling pathway	8/792	157/7206	0.0137615574079
ko04213	Longevity regulating pathway - multiple species	17/792	86/7206	0.0141578179212
ko04916	Melanogenesis	25/792	142/7206	0.0145894317405
ko04630	Jak-STAT signaling pathway	6/792	132/7206	0.0158585665676
ko04666	Fc gamma R-mediated phagocytosis	22/792	122/7206	0.0184115295083
ko04015	Rap1 signaling pathway	43/792	278/7206	0.0186619716109
ko04217	Necroptosis	10/792	178/7206	0.0202591699669
ko04919	Thyroid hormone signaling pathway	25/792	143/7206	0.0204682526243
ko04973	Carbohydrate digestion and absorption	10/792	42/7206	0.020987962933
ko05010	Alzheimer's disease	33/792	202/7206	0.0216310784659
ko04145	Phagosome	9/792	162/7206	0.0218650071414
ko04142	Lysosome	8/792	151/7206	0.0242622919923
ko00280	Valine, leucine and isoleucine degradation	1/792	54/7206	0.026608268499
ko04114	Oocyte meiosis	24/792	139/7206	0.0270315510443
ko05169	Epstein-Barr virus infection	13/792	206/7206	0.0308935466613
ko05410	Hypertrophic cardiomyopathy (HCM)	18/792	100/7206	0.0344137629063
ko05162	Measles	6/792	120/7206	0.0376349128803
ko04722	Neurotrophin signaling pathway	26/792	160/7206	0.0398022282358
ko04626	Plant-pathogen interaction	5/792	18/7206	0.0401844529915
ko05130	Pathogenic Escherichia coli infection	3/792	77/7206	0.0430361876188
ko04976	Bile secretion	15/792	80/7206	0.044944397768
ko00515	Mannose type O-glycan biosynthesis	6/792	25/7206	0.0494177101488