ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	122/635	423/7206	2.38901948884e-35
ko05033	Nicotine addiction	40/635	56/7206	2.17580944239e-30
ko04724	Glutamatergic synapse	63/635	152/7206	4.88132876457e-28
ko04728	Dopaminergic synapse	56/635	185/7206	2.09382180986e-17
ko04727	GABAergic synapse	41/635	110/7206	1.35400953244e-16
ko05032	Morphine addiction	41/635	110/7206	1.35400953244e-16
ko04721	Synaptic vesicle cycle	34/635	80/7206	5.26504608794e-16
ko04723	Retrograde endocannabinoid signaling	51/635	175/7206	3.46926198872e-15
ko04713	Circadian entrainment	44/635	136/7206	4.43708589648e-15
ko04024	cAMP signaling pathway	64/635	279/7206	2.7174321545e-13
ko04725	Cholinergic synapse	42/635	160/7206	4.53833182649e-11
ko04911	Insulin secretion	34/635	117/7206	1.74212328582e-10
ko05030	Cocaine addiction	26/635	73/7206	1.81646304572e-10
ko05031	Amphetamine addiction	28/635	91/7206	1.74119658927e-09
ko04020	Calcium signaling pathway	53/635	265/7206	7.2284057391e-09
ko04726	Serotonergic synapse	34/635	137/7206	1.59317824365e-08
ko04261	Adrenergic signaling in cardiomyocytes	44/635	205/7206	1.99270263185e-08
ko04742	Taste transduction	21/635	61/7206	2.10671370373e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	23/635	74/7206	4.06289435448e-08
ko04720	Long-term potentiation	27/635	99/7206	5.9811783597e-08
ko04010	MAPK signaling pathway	56/635	321/7206	4.87513858967e-07
ko04514	Cell adhesion molecules (CAMs)	30/635	130/7206	6.21082023558e-07
ko04921	Oxytocin signaling pathway	41/635	209/7206	7.06729002769e-07
ko04360	Axon guidance	44/635	233/7206	8.4277495684e-07
ko04970	Salivary secretion	23/635	95/7206	5.41110210455e-06
ko04730	Long-term depression	20/635	78/7206	8.77983971491e-06
ko04972	Pancreatic secretion	24/635	111/7206	2.65631263422e-05
ko03040	Spliceosome	1/635	145/7206	4.00060700207e-05
ko03013	RNA transport	2/635	166/7206	4.41948307683e-05
ko04060	Cytokine-cytokine receptor interaction	4/635	191/7206	0.000230607710698
ko04072	Phospholipase D signaling pathway	33/635	197/7206	0.000286808156682
ko05203	Viral carcinogenesis	9/635	277/7206	0.000315181238038
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/635	79/7206	0.00041496514427
ko04915	Estrogen signaling pathway	24/635	131/7206	0.000474265649338
ko04022	cGMP-PKG signaling pathway	34/635	216/7206	0.000851293790752
ko04971	Gastric acid secretion	19/635	98/7206	0.000887557590411
ko05322	Systemic lupus erythematosus	3/635	151/7206	0.00115021269884
ko01200	Carbon metabolism	2/635	128/7206	0.00132000716393
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/635	59/7206	0.00154068041045
ko04070	Phosphatidylinositol signaling system	20/635	112/7206	0.0020210872131
ko04540	Gap junction	22/635	128/7206	0.00228468216832
ko04925	Aldosterone synthesis and secretion	19/635	105/7206	0.00248546914419
ko04621	NOD-like receptor signaling pathway	4/635	157/7206	0.00249332917293
ko04964	Proximal tubule bicarbonate reclamation	8/635	29/7206	0.00280932182781
ko05205	Proteoglycans in cancer	11/635	271/7206	0.00302281912528
ko04260	Cardiac muscle contraction	18/635	98/7206	0.00319230855638
ko04014	Ras signaling pathway	39/635	279/7206	0.00342556917538
ko04071	Sphingolipid signaling pathway	25/635	162/7206	0.00478979517034
ko05168	Herpes simplex infection	6/635	182/7206	0.00501764358658
ko05164	Influenza A	5/635	167/7206	0.00514010672839
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/635	14/7206	0.00533878744534
ko00240	Pyrimidine metabolism	2/635	110/7206	0.00569374938859
ko04966	Collecting duct acid secretion	7/635	26/7206	0.00593372470915
ko03018	RNA degradation	1/635	84/7206	0.00617964417036
ko01230	Biosynthesis of amino acids	1/635	85/7206	0.0061985821484
ko04015	Rap1 signaling pathway	38/635	278/7206	0.00657188664463
ko04120	Ubiquitin mediated proteolysis	4/635	138/7206	0.00925433497808
ko04141	Protein processing in endoplasmic reticulum	7/635	184/7206	0.0117852161602
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/635	182/7206	0.0160884433956
ko04214	Apoptosis - fly	1/635	72/7206	0.0194749224323
ko00310	Lysine degradation	1/635	73/7206	0.0198263634866
ko00010	Glycolysis / Gluconeogenesis	1/635	74/7206	0.0203429798278
ko04146	Peroxisome	2/635	89/7206	0.0225466076799
ko05414	Dilated cardiomyopathy	17/635	112/7206	0.0267727566937
ko05010	Alzheimer's disease	27/635	202/7206	0.0310440849432
ko04350	TGF-beta signaling pathway	3/635	103/7206	0.0334418283787
ko00562	Inositol phosphate metabolism	14/635	89/7206	0.0351147922656
ko02024	Quorum sensing	4/635	15/7206	0.0371765161462
ko00561	Glycerolipid metabolism	1/635	63/7206	0.0412836985536
ko04640	Hematopoietic cell lineage	1/635	64/7206	0.042047681958
ko04217	Necroptosis	8/635	178/7206	0.0431640095425
ko05169	Epstein-Barr virus infection	10/635	206/7206	0.044881237658
ko04064	NF-kappa B signaling pathway	3/635	96/7206	0.0452937809083
ko05034	Alcoholism	30/635	238/7206	0.0468521345525