ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	147/1163	423/7206	3.01193502765e-22
ko04724	Glutamatergic synapse	69/1163	152/7206	8.92289241087e-18
ko05032	Morphine addiction	52/1163	110/7206	1.3755297051e-14
ko04727	GABAergic synapse	51/1163	110/7206	6.58718540535e-14
ko05033	Nicotine addiction	33/1163	56/7206	3.44264255514e-13
ko04713	Circadian entrainment	57/1163	136/7206	4.65614645519e-13
ko04721	Synaptic vesicle cycle	37/1163	80/7206	2.07271438774e-10
ko04728	Dopaminergic synapse	64/1163	185/7206	4.22348400495e-10
ko04744	Phototransduction	22/1163	36/7206	1.20144912509e-09
ko04723	Retrograde endocannabinoid signaling	60/1163	175/7206	2.24772782952e-09
ko04020	Calcium signaling pathway	81/1163	265/7206	2.27726564446e-09
ko04921	Oxytocin signaling pathway	68/1163	209/7206	2.59795991958e-09
ko04725	Cholinergic synapse	56/1163	160/7206	3.23084612142e-09
ko04024	cAMP signaling pathway	84/1163	279/7206	3.32026361766e-09
ko03010	Ribosome	1/1163	129/7206	4.18575791208e-09
ko04726	Serotonergic synapse	49/1163	137/7206	1.39357987771e-08
ko03040	Spliceosome	3/1163	145/7206	3.90618664849e-08
ko04110	Cell cycle	4/1163	145/7206	2.96077656271e-07
ko03013	RNA transport	6/1163	166/7206	5.3183635905e-07
ko04911	Insulin secretion	41/1163	117/7206	6.54640388435e-07
ko05322	Systemic lupus erythematosus	5/1163	151/7206	8.87522668318e-07
ko05203	Viral carcinogenesis	18/1163	277/7206	1.57332987213e-06
ko04966	Collecting duct acid secretion	15/1163	26/7206	1.58933858842e-06
ko04022	cGMP-PKG signaling pathway	60/1163	216/7206	1.21794339623e-05
ko04261	Adrenergic signaling in cardiomyocytes	57/1163	205/7206	1.80468622656e-05
ko03008	Ribosome biogenesis in eukaryotes	1/1163	79/7206	2.0626171083e-05
ko05031	Amphetamine addiction	31/1163	91/7206	2.10638792927e-05
ko04720	Long-term potentiation	33/1163	99/7206	2.23923671526e-05
ko04070	Phosphatidylinositol signaling system	36/1163	112/7206	2.29417422033e-05
ko04970	Salivary secretion	32/1163	95/7206	2.76041137243e-05
ko04742	Taste transduction	23/1163	61/7206	5.75340871767e-05
ko05169	Epstein-Barr virus infection	14/1163	206/7206	7.08749348785e-05
ko04925	Aldosterone synthesis and secretion	33/1163	105/7206	8.03955529101e-05
ko04745	Phototransduction - fly	16/1163	38/7206	0.000123354762913
ko04971	Gastric acid secretion	31/1163	98/7206	0.000134562426778
ko05168	Herpes simplex infection	12/1163	182/7206	0.000139489808456
ko04730	Long-term depression	26/1163	78/7206	0.000149994814851
ko04710	Circadian rhythm	17/1163	43/7206	0.000193123572853
ko04964	Proximal tubule bicarbonate reclamation	13/1163	29/7206	0.000251606309872
ko04514	Cell adhesion molecules (CAMs)	37/1163	130/7206	0.000399686978516
ko04141	Protein processing in endoplasmic reticulum	14/1163	184/7206	0.00075318576579
ko04072	Phospholipase D signaling pathway	50/1163	197/7206	0.000766457326363
ko04010	MAPK signaling pathway	74/1163	321/7206	0.00105657219433
ko03050	Proteasome	1/1163	54/7206	0.00130929623765
ko00120	Primary bile acid biosynthesis	9/1163	20/7206	0.00222460503438
ko04922	Glucagon signaling pathway	34/1163	128/7206	0.00226711978002
ko05161	Hepatitis B	14/1163	173/7206	0.00230641501422
ko04371	Apelin signaling pathway	44/1163	177/7206	0.00252850224542
ko01040	Biosynthesis of unsaturated fatty acids	10/1163	25/7206	0.00367154755057
ko04972	Pancreatic secretion	30/1163	111/7206	0.00379379680059
ko05164	Influenza A	14/1163	167/7206	0.00396798511776
ko04626	Plant-pathogen interaction	8/1163	18/7206	0.00430406767339
ko05166	HTLV-I infection	30/1163	292/7206	0.00437827297697
ko03420	Nucleotide excision repair	1/1163	46/7206	0.00447020503764
ko04014	Ras signaling pathway	63/1163	279/7206	0.00459802561961
ko04657	IL-17 signaling pathway	5/1163	87/7206	0.00502551518459
ko05110	Vibrio cholerae infection	19/1163	63/7206	0.00508791350519
ko04621	NOD-like receptor signaling pathway	13/1163	157/7206	0.00576005097031
ko05030	Cocaine addiction	21/1163	73/7206	0.0059280235295
ko05200	Pathways in cancer	58/1163	492/7206	0.00623466632519
ko03022	Basal transcription factors	1/1163	44/7206	0.00669336347949
ko04120	Ubiquitin mediated proteolysis	11/1163	138/7206	0.00683589099292
ko05205	Proteoglycans in cancer	28/1163	271/7206	0.00692452634589
ko05130	Pathogenic Escherichia coli infection	4/1163	77/7206	0.00719843601767
ko04260	Cardiac muscle contraction	26/1163	98/7206	0.00804826325463
ko05162	Measles	9/1163	120/7206	0.00806561357964
ko04750	Inflammatory mediator regulation of TRP channels	31/1163	122/7206	0.00856310121395
ko00520	Amino sugar and nucleotide sugar metabolism	2/1163	55/7206	0.00865826630829
ko04214	Apoptosis - fly	4/1163	72/7206	0.00970034696778
ko05131	Shigellosis	5/1163	82/7206	0.00971120288092
ko04210	Apoptosis	17/1163	180/7206	0.0133198589901
ko04113	Meiosis - yeast	4/1163	70/7206	0.0135938681619
ko04330	Notch signaling pathway	3/1163	62/7206	0.0137043919085
ko04930	Type II diabetes mellitus	16/1163	54/7206	0.0138612056525
ko05014	Amyotrophic lateral sclerosis (ALS)	20/1163	74/7206	0.0161270543913
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1163	14/7206	0.0162888657931
ko05220	Chronic myeloid leukemia	6/1163	85/7206	0.0175814001689
ko05219	Bladder cancer	2/1163	48/7206	0.0177055408175
ko05217	Basal cell carcinoma	4/1163	68/7206	0.0191352234839
ko04740	Olfactory transduction	21/1163	80/7206	0.0205915602428
ko04350	TGF-beta signaling pathway	8/1163	103/7206	0.0207672499047
ko03410	Base excision repair	1/1163	38/7206	0.0236767158974
ko04550	Signaling pathways regulating pluripotency of stem cells	16/1163	165/7206	0.0239202033392
ko04136	Autophagy - other	10/1163	31/7206	0.0241569052847
ko04510	Focal adhesion	26/1163	240/7206	0.0252018807316
ko02010	ABC transporters	12/1163	39/7206	0.025424207377
ko04924	Renin secretion	22/1163	86/7206	0.0255417655237
ko05206	MicroRNAs in cancer	18/1163	177/7206	0.02931912121
ko04960	Aldosterone-regulated sodium reabsorption	12/1163	41/7206	0.0311788426215
ko00860	Porphyrin and chlorophyll metabolism	1/1163	34/7206	0.0334171068208
ko00830	Retinol metabolism	12/1163	42/7206	0.0352301170832
ko04064	NF-kappa B signaling pathway	8/1163	96/7206	0.0355924553967
ko04622	RIG-I-like receptor signaling pathway	4/1163	62/7206	0.0364416462599
ko00010	Glycolysis / Gluconeogenesis	19/1163	74/7206	0.0370031228659
ko05215	Prostate cancer	10/1163	111/7206	0.0374620326635
ko00562	Inositol phosphate metabolism	22/1163	89/7206	0.0406773463196
ko04915	Estrogen signaling pathway	30/1163	131/7206	0.0409124090473
ko04520	Adherens junction	9/1163	103/7206	0.0420491829009
ko04612	Antigen processing and presentation	6/1163	77/7206	0.0430066597627