ko pathway ratio_in_study ratio_in_pop p_value ko05340 Primary immunodeficiency 10/107 30/7206 7.97912890418e-12 ko04612 Antigen processing and presentation 13/107 77/7206 6.77882427801e-11 ko05168 Herpes simplex infection 16/107 182/7206 8.2676692551e-09 ko05164 Influenza A 15/107 167/7206 1.88961393425e-08 ko05145 Toxoplasmosis 12/107 126/7206 2.92850558091e-07 ko04621 NOD-like receptor signaling pathway 12/107 157/7206 3.12202117171e-06 ko04380 Osteoclast differentiation 11/107 134/7206 4.13170500717e-06 ko04060 Cytokine-cytokine receptor interaction 13/107 191/7206 4.32447654056e-06 ko05162 Measles 10/107 120/7206 1.01505001838e-05 ko04064 NF-kappa B signaling pathway 9/107 96/7206 1.10731019555e-05 ko03050 Proteasome 7/107 54/7206 1.30359875335e-05 ko05152 Tuberculosis 12/107 187/7206 1.88586663684e-05 ko04630 Jak-STAT signaling pathway 10/107 132/7206 2.35330840212e-05 ko04622 RIG-I-like receptor signaling pathway 7/107 62/7206 3.28401898453e-05 ko05161 Hepatitis B 11/107 173/7206 4.67058421488e-05 ko04217 Necroptosis 11/107 178/7206 6.06303329555e-05 ko04620 Toll-like receptor signaling pathway 8/107 100/7206 0.000109139483694 ko04672 Intestinal immune network for IgA production 5/107 37/7206 0.000196265400118 ko05330 Allograft rejection 4/107 24/7206 0.000388396232169 ko05160 Hepatitis C 9/107 153/7206 0.000421883267345 ko05140 Leishmaniasis 6/107 75/7206 0.000817357567697 ko05320 Autoimmune thyroid disease 4/107 29/7206 0.00081999440989 ko05321 Inflammatory bowel disease (IBD) 5/107 56/7206 0.00137564395783 ko04668 TNF signaling pathway 7/107 120/7206 0.00196559535792 ko05167 Kaposi's sarcoma-associated herpesvirus infection 9/107 191/7206 0.0020449641026 ko04660 T cell receptor signaling pathway 7/107 124/7206 0.00236990679205 ko04145 Phagosome 8/107 162/7206 0.0027145714698 ko04658 Th1 and Th2 cell differentiation 6/107 96/7206 0.0029284572985 ko04623 Cytosolic DNA-sensing pathway 4/107 41/7206 0.00305038814824 ko05142 Chagas disease (American trypanosomiasis) 7/107 130/7206 0.00309341679952 ko04659 Th17 cell differentiation 6/107 106/7206 0.00478405754386 ko05133 Pertussis 5/107 87/7206 0.00926715214484 ko04062 Chemokine signaling pathway 8/107 201/7206 0.00982374002964 ko00966 Glucosinolate biosynthesis 1/107 1/7206 0.0148487371635 ko04210 Apoptosis 7/107 180/7206 0.0173308684334 ko04142 Lysosome 6/107 151/7206 0.0245204251465 ko05310 Asthma 2/107 17/7206 0.0256920906441 ko05332 Graft-versus-host disease 2/107 18/7206 0.0286275678936 ko05144 Malaria 3/107 45/7206 0.0287748308277 ko05131 Shigellosis 4/107 82/7206 0.033235949531 ko00120 Primary bile acid biosynthesis 2/107 20/7206 0.034875987849 ko00380 Tryptophan metabolism 3/107 50/7206 0.0376998879538 ko04917 Prolactin signaling pathway 4/107 87/7206 0.0400109861649 ko05416 Viral myocarditis 3/107 55/7206 0.0478744873335