ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	152/964	423/7206	2.75666294095e-34
ko04724	Glutamatergic synapse	82/964	152/7206	2.52913138468e-33
ko05033	Nicotine addiction	47/964	56/7206	7.3402817313e-33
ko05032	Morphine addiction	64/964	110/7206	9.66897701451e-29
ko04727	GABAergic synapse	62/964	110/7206	8.23592450051e-27
ko04713	Circadian entrainment	65/964	136/7206	1.00470915039e-22
ko04728	Dopaminergic synapse	76/964	185/7206	2.45312280235e-21
ko04723	Retrograde endocannabinoid signaling	73/964	175/7206	5.34626341643e-21
ko04725	Cholinergic synapse	61/964	160/7206	1.7317630674e-15
ko04744	Phototransduction	25/964	36/7206	1.50825967115e-14
ko04020	Calcium signaling pathway	82/964	265/7206	4.20961911446e-14
ko04024	cAMP signaling pathway	84/964	279/7206	1.05199602892e-13
ko04721	Synaptic vesicle cycle	37/964	80/7206	6.80757385348e-13
ko04726	Serotonergic synapse	51/964	137/7206	1.12841520676e-12
ko04742	Taste transduction	30/964	61/7206	1.49602902126e-11
ko04911	Insulin secretion	44/964	117/7206	2.7879837771e-11
ko04921	Oxytocin signaling pathway	64/964	209/7206	3.92145571512e-11
ko04261	Adrenergic signaling in cardiomyocytes	62/964	205/7206	1.94208294539e-10
ko05031	Amphetamine addiction	35/964	91/7206	1.50788210949e-09
ko05030	Cocaine addiction	29/964	73/7206	1.64034733214e-08
ko04720	Long-term potentiation	35/964	99/7206	1.98788060839e-08
ko04010	MAPK signaling pathway	78/964	321/7206	5.54312969098e-08
ko03040	Spliceosome	2/964	145/7206	3.85403621357e-07
ko05203	Viral carcinogenesis	12/964	277/7206	5.34415943829e-07
ko04072	Phospholipase D signaling pathway	51/964	197/7206	1.9446787356e-06
ko03013	RNA transport	5/964	166/7206	7.86133900227e-06
ko05322	Systemic lupus erythematosus	4/964	151/7206	8.95404836561e-06
ko04970	Salivary secretion	29/964	95/7206	1.07895393979e-05
ko04514	Cell adhesion molecules (CAMs)	36/964	130/7206	1.17348953243e-05
ko04925	Aldosterone synthesis and secretion	31/964	105/7206	1.47176462557e-05
ko04972	Pancreatic secretion	32/964	111/7206	1.4805472564e-05
ko04022	cGMP-PKG signaling pathway	51/964	216/7206	3.87937785843e-05
ko04070	Phosphatidylinositol signaling system	31/964	112/7206	5.77131009711e-05
ko04260	Cardiac muscle contraction	28/964	98/7206	6.43054460166e-05
ko04711	Circadian rhythm - fly	8/964	13/7206	6.8834353166e-05
ko04710	Circadian rhythm	16/964	43/7206	7.14763820545e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/964	79/7206	7.22271333991e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	23/964	74/7206	8.12000979423e-05
ko05205	Proteoglycans in cancer	17/964	271/7206	0.000178379770789
ko04110	Cell cycle	6/964	145/7206	0.000301295851099
ko04612	Antigen processing and presentation	1/964	77/7206	0.000308433382732
ko04621	NOD-like receptor signaling pathway	7/964	157/7206	0.000319980747411
ko04610	Complement and coagulation cascades	1/964	79/7206	0.000325135017991
ko03008	Ribosome biogenesis in eukaryotes	1/964	79/7206	0.000325135017991
ko05164	Influenza A	8/964	167/7206	0.000328387365357
ko04060	Cytokine-cytokine receptor interaction	10/964	191/7206	0.000330142375329
ko04971	Gastric acid secretion	26/964	98/7206	0.00045211992151
ko04360	Axon guidance	50/964	233/7206	0.000556429777714
ko04730	Long-term depression	22/964	78/7206	0.000568447952642
ko04141	Protein processing in endoplasmic reticulum	10/964	184/7206	0.000606034542529
ko04740	Olfactory transduction	22/964	80/7206	0.000716067450303
ko04014	Ras signaling pathway	57/964	279/7206	0.000842458338839
ko05414	Dilated cardiomyopathy	28/964	112/7206	0.00105668457994
ko04930	Type II diabetes mellitus	16/964	54/7206	0.00177266998855
ko04915	Estrogen signaling pathway	30/964	131/7206	0.00260168531231
ko04964	Proximal tubule bicarbonate reclamation	10/964	29/7206	0.00316148674946
ko05169	Epstein-Barr virus infection	14/964	206/7206	0.00345576428113
ko05131	Shigellosis	3/964	82/7206	0.00517504792785
ko04120	Ubiquitin mediated proteolysis	8/964	138/7206	0.00531250249769
ko05168	Herpes simplex infection	12/964	182/7206	0.00546172759821
ko04064	NF-kappa B signaling pathway	4/964	96/7206	0.00581209422842
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/964	14/7206	0.00650852151724
ko05410	Hypertrophic cardiomyopathy (HCM)	23/964	100/7206	0.00731717513527
ko00562	Inositol phosphate metabolism	21/964	89/7206	0.00731839264031
ko05016	Huntington's disease	16/964	215/7206	0.00789016693697
ko05161	Hepatitis B	12/964	173/7206	0.00910025862693
ko05130	Pathogenic Escherichia coli infection	3/964	77/7206	0.0105363526792
ko00240	Pyrimidine metabolism	6/964	110/7206	0.0105578658626
ko05133	Pertussis	4/964	87/7206	0.0108256476137
ko00590	Arachidonic acid metabolism	1/964	52/7206	0.0119287762646
ko00330	Arginine and proline metabolism	2/964	61/7206	0.0135619984189
ko05162	Measles	7/964	120/7206	0.0139645517467
ko04750	Inflammatory mediator regulation of TRP channels	26/964	122/7206	0.0148688654067
ko05140	Leishmaniasis	3/964	75/7206	0.015326303247
ko03420	Nucleotide excision repair	1/964	46/7206	0.0166217358711
ko04540	Gap junction	27/964	128/7206	0.0173577903688
ko04350	TGF-beta signaling pathway	6/964	103/7206	0.019288063162
ko04932	Non-alcoholic fatty liver disease (NAFLD)	14/964	182/7206	0.0202474975531
ko03320	PPAR signaling pathway	3/964	69/7206	0.0207043089985
ko04976	Bile secretion	18/964	80/7206	0.020728528175
ko04810	Regulation of actin cytoskeleton	23/964	264/7206	0.0211761756659
ko04918	Thyroid hormone synthesis	19/964	86/7206	0.0243526835085
ko03022	Basal transcription factors	1/964	44/7206	0.0245674524695
ko00071	Fatty acid degradation	1/964	45/7206	0.0251122022326
ko04371	Apelin signaling pathway	34/964	177/7206	0.025158744592
ko05034	Alcoholism	44/964	238/7206	0.025335903589
ko04217	Necroptosis	14/964	178/7206	0.0256978172132
ko04146	Peroxisome	5/964	89/7206	0.0275306696967
ko00480	Glutathione metabolism	2/964	55/7206	0.0279312874725
ko05416	Viral myocarditis	2/964	55/7206	0.0279312874725
ko05321	Inflammatory bowel disease (IBD)	2/964	56/7206	0.0282010026606
ko04745	Phototransduction - fly	10/964	38/7206	0.028574723671
ko04670	Leukocyte transendothelial migration	11/964	151/7206	0.0286321735613
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/964	59/7206	0.0316513992656
ko05132	Salmonella infection	6/964	98/7206	0.035048903982
ko00980	Metabolism of xenobiotics by cytochrome P450	1/964	40/7206	0.036114831919
ko00140	Steroid hormone biosynthesis	1/964	41/7206	0.036250622242
ko04657	IL-17 signaling pathway	5/964	87/7206	0.0377073973111
ko04115	p53 signaling pathway	4/964	74/7206	0.0392950555007
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/964	15/7206	0.0401487650297
ko04640	Hematopoietic cell lineage	3/964	64/7206	0.040709949448