ko pathway ratio_in_study ratio_in_pop p_value ko04724 Glutamatergic synapse 16/142 152/7206 3.85927084232e-08 ko04720 Long-term potentiation 11/142 99/7206 3.37794165889e-06 ko04925 Aldosterone synthesis and secretion 11/142 105/7206 6.03571957394e-06 ko04745 Phototransduction - fly 7/142 38/7206 7.53403793804e-06 ko04070 Phosphatidylinositol signaling system 11/142 112/7206 1.13012004208e-05 ko04020 Calcium signaling pathway 17/142 265/7206 1.58673610477e-05 ko00562 Inositol phosphate metabolism 9/142 89/7206 5.79445387489e-05 ko04723 Retrograde endocannabinoid signaling 12/142 175/7206 0.000161510848893 ko04921 Oxytocin signaling pathway 13/142 209/7206 0.000227735511727 ko04727 GABAergic synapse 9/142 110/7206 0.000298301426578 ko04713 Circadian entrainment 10/142 136/7206 0.000329594447916 ko05031 Amphetamine addiction 8/142 91/7206 0.00039970882403 ko04911 Insulin secretion 9/142 117/7206 0.000472237779264 ko04970 Salivary secretion 8/142 95/7206 0.000535120266249 ko05033 Nicotine addiction 6/142 56/7206 0.000760539900347 ko04730 Long-term depression 7/142 78/7206 0.000818288255735 ko04728 Dopaminergic synapse 11/142 185/7206 0.00101596674336 ko05032 Morphine addiction 8/142 110/7206 0.0014083426029 ko04924 Renin secretion 7/142 86/7206 0.00146052403142 ko04726 Serotonergic synapse 9/142 137/7206 0.00146925393793 ko04261 Adrenergic signaling in cardiomyocytes 11/142 205/7206 0.00231674047058 ko04912 GnRH signaling pathway 8/142 122/7206 0.00271671905707 ko04320 Dorso-ventral axis formation 4/142 31/7206 0.00300773027858 ko04971 Gastric acid secretion 7/142 98/7206 0.00309285997815 ko04022 cGMP-PKG signaling pathway 11/142 216/7206 0.00347374708317 ko04922 Glucagon signaling pathway 8/142 128/7206 0.0036551034077 ko04915 Estrogen signaling pathway 8/142 131/7206 0.00420983220631 ko04725 Cholinergic synapse 9/142 160/7206 0.0042195620091 ko05231 Choline metabolism in cancer 8/142 134/7206 0.00482743426798 ko04012 ErbB signaling pathway 7/142 109/7206 0.0055716323912 ko04972 Pancreatic secretion 7/142 111/7206 0.00614814654934 ko04750 Inflammatory mediator regulation of TRP channels 7/142 122/7206 0.010147835172 ko04080 Neuroactive ligand-receptor interaction 16/142 423/7206 0.0105137785702 ko05030 Cocaine addiction 5/142 73/7206 0.0142385524283 ko00512 Mucin type O-glycan biosynthesis 3/142 29/7206 0.0188253808397 ko05214 Glioma 5/142 79/7206 0.019464876758 ko04930 Type II diabetes mellitus 4/142 54/7206 0.0213590679169 ko04918 Thyroid hormone synthesis 5/142 86/7206 0.026991453267 ko04742 Taste transduction 4/142 61/7206 0.0317428994156 ko04270 Vascular smooth muscle contraction 7/142 154/7206 0.0321351841092 ko04666 Fc gamma R-mediated phagocytosis 6/142 122/7206 0.0330606002063 ko04010 MAPK signaling pathway 12/142 321/7206 0.0354391536991 ko04139 Mitophagy - yeast 3/142 37/7206 0.0357380770728 ko04540 Gap junction 6/142 128/7206 0.040364949576 ko00564 Glycerophospholipid metabolism 5/142 99/7206 0.0453823673069 ko00513 Various types of N-glycan biosynthesis 3/142 42/7206 0.0492114360325