ko pathway ratio_in_study ratio_in_pop p_value ko04976 Bile secretion 18/284 80/7206 1.20338158636e-09 ko04974 Protein digestion and absorption 18/284 96/7206 2.61612730499e-08 ko00643 Styrene degradation 4/284 4/7206 2.36398568265e-06 ko00140 Steroid hormone biosynthesis 10/284 41/7206 2.92471753826e-06 ko04614 Renin-angiotensin system 7/284 18/7206 3.004595218e-06 ko00350 Tyrosine metabolism 9/284 33/7206 3.38619196055e-06 ko04975 Fat digestion and absorption 9/284 35/7206 5.78290873355e-06 ko05204 Chemical carcinogenesis 10/284 48/7206 1.33571733332e-05 ko04978 Mineral absorption 9/284 40/7206 1.882514719e-05 ko00983 Drug metabolism - other enzymes 9/284 42/7206 2.8640009678e-05 ko00830 Retinol metabolism 9/284 42/7206 2.8640009678e-05 ko00120 Primary bile acid biosynthesis 6/284 20/7206 8.63266518984e-05 ko04972 Pancreatic secretion 14/284 111/7206 0.000106478000021 ko02010 ABC transporters 8/284 39/7206 0.000111713037585 ko00380 Tryptophan metabolism 9/284 50/7206 0.000121978450574 ko00980 Metabolism of xenobiotics by cytochrome P450 8/284 40/7206 0.000134935010182 ko05200 Pathways in cancer 6/284 492/7206 0.000430191741401 ko00260 Glycine, serine and threonine metabolism 8/284 48/7206 0.000503537713248 ko00982 Drug metabolism - cytochrome P450 7/284 37/7206 0.000510242284549 ko00591 Linoleic acid metabolism 5/284 22/7206 0.00139082158705 ko00053 Ascorbate and aldarate metabolism 5/284 22/7206 0.00139082158705 ko03320 PPAR signaling pathway 9/284 69/7206 0.00143319285962 ko04360 Axon guidance 1/284 233/7206 0.00162565776254 ko00360 Phenylalanine metabolism 4/284 17/7206 0.00374285507082 ko00480 Glutathione metabolism 7/284 55/7206 0.00549600732456 ko00920 Sulfur metabolism 3/284 10/7206 0.00591407101475 ko05203 Viral carcinogenesis 3/284 277/7206 0.00704656297807 ko04015 Rap1 signaling pathway 3/284 278/7206 0.00704789261593 ko04010 MAPK signaling pathway 4/284 321/7206 0.00751366367067 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 3/284 11/7206 0.00789715592473 ko00290 Valine, leucine and isoleucine biosynthesis 2/284 4/7206 0.0088104343072 ko00965 Betalain biosynthesis 2/284 4/7206 0.0088104343072 ko04977 Vitamin digestion and absorption 4/284 22/7206 0.00985330734288 ko04217 Necroptosis 1/284 178/7206 0.010384195332 ko04310 Wnt signaling pathway 1/284 181/7206 0.0104923693423 ko04150 mTOR signaling pathway 1/284 184/7206 0.0107599081129 ko04744 Phototransduction 5/284 36/7206 0.0127032323105 ko00232 Caffeine metabolism 2/284 5/7206 0.0143033486504 ko05224 Breast cancer 1/284 174/7206 0.0155845637711 ko00040 Pentose and glucuronate interconversions 4/284 26/7206 0.0178053888659 ko04722 Neurotrophin signaling pathway 1/284 160/7206 0.0218446768467 ko00565 Ether lipid metabolism 5/284 42/7206 0.0236918202598 ko05010 Alzheimer's disease 2/284 202/7206 0.0254566855472 ko04710 Circadian rhythm 5/284 43/7206 0.0259745529899 ko05322 Systemic lupus erythematosus 1/284 151/7206 0.0316777533763 ko01200 Carbon metabolism 10/284 128/7206 0.0348336110912 ko05152 Tuberculosis 2/284 187/7206 0.0350295743683 ko05202 Transcriptional misregulation in cancer 2/284 188/7206 0.0350978885015 ko00592 alpha-Linolenic acid metabolism 3/284 19/7206 0.0367722369888 ko04740 Olfactory transduction 7/284 80/7206 0.0376198873639 ko00901 Indole alkaloid biosynthesis 1/284 1/7206 0.0394116014433 ko00401 Novobiocin biosynthesis 1/284 1/7206 0.0394116014433 ko00860 Porphyrin and chlorophyll metabolism 4/284 34/7206 0.0432772825082 ko04114 Oocyte meiosis 1/284 139/7206 0.0451238570782 ko00100 Steroid biosynthesis 3/284 21/7206 0.0476566083184 ko04218 Cellular senescence 2/284 177/7206 0.0489637860226