ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04974	Protein digestion and absorption	33/545	96/7206	2.46415814004e-14
ko04080	Neuroactive ligand-receptor interaction	73/545	423/7206	7.55710271356e-12
ko04713	Circadian entrainment	34/545	136/7206	2.37403269843e-10
ko04020	Calcium signaling pathway	51/545	265/7206	2.56273678123e-10
ko04911	Insulin secretion	30/545	117/7206	1.44679871629e-09
ko04724	Glutamatergic synapse	34/545	152/7206	5.50149416669e-09
ko04725	Cholinergic synapse	34/545	160/7206	2.19200155881e-08
ko04261	Adrenergic signaling in cardiomyocytes	39/545	205/7206	5.05344499406e-08
ko05033	Nicotine addiction	17/545	56/7206	4.10412155211e-07
ko04727	GABAergic synapse	25/545	110/7206	4.354447687e-07
ko04260	Cardiac muscle contraction	22/545	98/7206	2.67832330176e-06
ko04971	Gastric acid secretion	22/545	98/7206	2.67832330176e-06
ko04728	Dopaminergic synapse	33/545	185/7206	2.90353841014e-06
ko04921	Oxytocin signaling pathway	36/545	209/7206	3.11427008311e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/545	79/7206	4.3775811074e-06
ko04970	Salivary secretion	21/545	95/7206	5.85655395648e-06
ko04512	ECM-receptor interaction	18/545	79/7206	1.74521561788e-05
ko04721	Synaptic vesicle cycle	18/545	80/7206	2.09673200457e-05
ko04740	Olfactory transduction	18/545	80/7206	2.09673200457e-05
ko05031	Amphetamine addiction	19/545	91/7206	3.81012996713e-05
ko04022	cGMP-PKG signaling pathway	33/545	216/7206	0.000108157971819
ko04720	Long-term potentiation	19/545	99/7206	0.000127107712078
ko05322	Systemic lupus erythematosus	1/545	151/7206	0.000138420914397
ko05410	Hypertrophic cardiomyopathy (HCM)	19/545	100/7206	0.000146119678643
ko05168	Herpes simplex infection	2/545	182/7206	0.000156587000933
ko04024	cAMP signaling pathway	39/545	279/7206	0.000175571563681
ko04964	Proximal tubule bicarbonate reclamation	9/545	29/7206	0.000192105941033
ko03040	Spliceosome	1/545	145/7206	0.000204573481431
ko04976	Bile secretion	16/545	80/7206	0.000261581858727
ko04925	Aldosterone synthesis and secretion	19/545	105/7206	0.000283671547519
ko04514	Cell adhesion molecules (CAMs)	22/545	130/7206	0.000296224733122
ko05014	Amyotrophic lateral sclerosis (ALS)	15/545	74/7206	0.000347269768585
ko05414	Dilated cardiomyopathy	20/545	112/7206	0.000377028518119
ko04745	Phototransduction - fly	10/545	38/7206	0.000383441800668
ko04120	Ubiquitin mediated proteolysis	1/545	138/7206	0.000459785210841
ko04978	Mineral absorption	10/545	40/7206	0.000599175414895
ko04972	Pancreatic secretion	19/545	111/7206	0.000738430928781
ko04726	Serotonergic synapse	22/545	137/7206	0.000794092601867
ko05032	Morphine addiction	18/545	110/7206	0.00155712634465
ko05203	Viral carcinogenesis	8/545	277/7206	0.00155941932233
ko03013	RNA transport	3/545	166/7206	0.00165777512222
ko04730	Long-term depression	14/545	78/7206	0.00189427403848
ko04723	Retrograde endocannabinoid signaling	25/545	175/7206	0.00198556088119
ko04140	Autophagy - animal	3/545	164/7206	0.00239481945744
ko04924	Renin secretion	15/545	86/7206	0.0028906198085
ko05030	Cocaine addiction	13/545	73/7206	0.00292177300607
ko04010	MAPK signaling pathway	39/545	321/7206	0.00327097154102
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/545	59/7206	0.00416909098958
ko05161	Hepatitis B	4/545	173/7206	0.00510002523154
ko04110	Cell cycle	3/545	145/7206	0.00652333927681
ko04550	Signaling pathways regulating pluripotency of stem cells	4/545	165/7206	0.00694762201039
ko04360	Axon guidance	29/545	233/7206	0.00758252794879
ko05162	Measles	2/545	120/7206	0.00818280936488
ko05166	HTLV-I infection	11/545	292/7206	0.00912094281596
ko04932	Non-alcoholic fatty liver disease (NAFLD)	5/545	182/7206	0.00979011511016
ko04960	Aldosterone-regulated sodium reabsorption	8/545	41/7206	0.0104739580733
ko04973	Carbohydrate digestion and absorption	8/545	42/7206	0.012107479681
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/545	14/7206	0.017577852133
ko04630	Jak-STAT signaling pathway	3/545	132/7206	0.0182661244982
ko04930	Type II diabetes mellitus	9/545	54/7206	0.0187991261557
ko04270	Vascular smooth muscle contraction	20/545	154/7206	0.0191626550739
ko04150	mTOR signaling pathway	6/545	184/7206	0.0228336518664
ko04141	Protein processing in endoplasmic reticulum	6/545	184/7206	0.0228336518664
ko04742	Taste transduction	10/545	61/7206	0.0233153824013
ko04914	Progesterone-mediated oocyte maturation	2/545	104/7206	0.0233767760829
ko05164	Influenza A	5/545	167/7206	0.0246813982102
ko04068	FoxO signaling pathway	5/545	167/7206	0.0246813982102
ko00190	Oxidative phosphorylation	3/545	127/7206	0.0254962176754
ko04922	Glucagon signaling pathway	17/545	128/7206	0.0259805303416
ko05130	Pathogenic Escherichia coli infection	1/545	77/7206	0.0289751730782
ko05010	Alzheimer's disease	24/545	202/7206	0.0293033598016
ko04610	Complement and coagulation cascades	1/545	79/7206	0.0294764241819
ko00030	Pentose phosphate pathway	6/545	32/7206	0.0304588272527
ko04621	NOD-like receptor signaling pathway	5/545	157/7206	0.0319952347928
ko00140	Steroid hormone biosynthesis	7/545	41/7206	0.032228943798
ko04620	Toll-like receptor signaling pathway	2/545	100/7206	0.0334642185931
ko05416	Viral myocarditis	9/545	55/7206	0.0340312955986
ko04916	Melanogenesis	18/545	142/7206	0.0348292410739
ko05418	Fluid shear stress and atherosclerosis	6/545	173/7206	0.0401409930601
ko04214	Apoptosis - fly	1/545	72/7206	0.0419976940616
ko04626	Plant-pathogen interaction	4/545	18/7206	0.0422767607016
ko00310	Lysine degradation	1/545	73/7206	0.0423217281463
ko05140	Leishmaniasis	1/545	75/7206	0.0436606814681