ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	167/1047	423/7206	4.59205332843e-39
ko04724	Glutamatergic synapse	80/1047	152/7206	6.0682759028e-29
ko05033	Nicotine addiction	45/1047	56/7206	2.59415104297e-28
ko05032	Morphine addiction	61/1047	110/7206	6.79927033297e-24
ko04721	Synaptic vesicle cycle	48/1047	80/7206	4.74714366909e-21
ko04727	GABAergic synapse	57/1047	110/7206	1.80921199093e-20
ko04725	Cholinergic synapse	71/1047	160/7206	3.26082769829e-20
ko04713	Circadian entrainment	64/1047	136/7206	5.68841834529e-20
ko04728	Dopaminergic synapse	77/1047	185/7206	8.89851476761e-20
ko04723	Retrograde endocannabinoid signaling	72/1047	175/7206	3.20469328185e-18
ko04024	cAMP signaling pathway	93/1047	279/7206	5.64126533758e-16
ko04742	Taste transduction	36/1047	61/7206	9.05163076805e-16
ko04744	Phototransduction	26/1047	36/7206	7.38128650658e-15
ko04911	Insulin secretion	50/1047	117/7206	8.71890116884e-14
ko04726	Serotonergic synapse	55/1047	137/7206	1.18136967048e-13
ko04921	Oxytocin signaling pathway	69/1047	209/7206	8.59196845781e-12
ko04020	Calcium signaling pathway	81/1047	265/7206	1.41378264393e-11
ko05031	Amphetamine addiction	37/1047	91/7206	8.55192377083e-10
ko04261	Adrenergic signaling in cardiomyocytes	63/1047	205/7206	1.97396708445e-09
ko04720	Long-term potentiation	38/1047	99/7206	3.542956205e-09
ko03040	Spliceosome	2/1047	145/7206	6.47182386412e-08
ko04360	Axon guidance	63/1047	233/7206	3.82869572693e-07
ko05030	Cocaine addiction	28/1047	73/7206	4.17919264459e-07
ko04970	Salivary secretion	33/1047	95/7206	8.92472140073e-07
ko04925	Aldosterone synthesis and secretion	35/1047	105/7206	8.98585349419e-07
ko03013	RNA transport	5/1047	166/7206	1.06655470651e-06
ko05168	Herpes simplex infection	7/1047	182/7206	3.2916566655e-06
ko04740	Olfactory transduction	28/1047	80/7206	3.55764502011e-06
ko04971	Gastric acid secretion	32/1047	98/7206	4.25812254153e-06
ko05322	Systemic lupus erythematosus	5/1047	151/7206	1.04264769638e-05
ko04514	Cell adhesion molecules (CAMs)	38/1047	130/7206	1.27969199492e-05
ko04621	NOD-like receptor signaling pathway	6/1047	157/7206	1.69792324755e-05
ko04966	Collecting duct acid secretion	13/1047	26/7206	1.96519734021e-05
ko04010	MAPK signaling pathway	74/1047	321/7206	3.1176747018e-05
ko04972	Pancreatic secretion	33/1047	111/7206	3.15575385432e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	25/1047	74/7206	3.21290653607e-05
ko04070	Phosphatidylinositol signaling system	33/1047	112/7206	3.69450585265e-05
ko05203	Viral carcinogenesis	18/1047	277/7206	3.73462986019e-05
ko04120	Ubiquitin mediated proteolysis	5/1047	138/7206	4.28429568406e-05
ko05164	Influenza A	8/1047	167/7206	8.18026267618e-05
ko03008	Ribosome biogenesis in eukaryotes	1/1047	79/7206	8.33001843601e-05
ko04141	Protein processing in endoplasmic reticulum	10/1047	184/7206	0.000118250574516
ko04745	Phototransduction - fly	15/1047	38/7206	0.000141933116873
ko04022	cGMP-PKG signaling pathway	52/1047	216/7206	0.000167829617596
ko04072	Phospholipase D signaling pathway	48/1047	197/7206	0.000197671635022
ko04730	Long-term depression	24/1047	78/7206	0.000247878427805
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/1047	79/7206	0.000283502739361
ko04064	NF-kappa B signaling pathway	3/1047	96/7206	0.000381032345285
ko05205	Proteoglycans in cancer	20/1047	271/7206	0.000399583054515
ko04014	Ras signaling pathway	62/1047	279/7206	0.000483086645101
ko04060	Cytokine-cytokine receptor interaction	12/1047	191/7206	0.000528969750274
ko04260	Cardiac muscle contraction	27/1047	98/7206	0.000727574647434
ko04110	Cell cycle	8/1047	145/7206	0.000795049741912
ko04612	Antigen processing and presentation	2/1047	77/7206	0.000930203680616
ko04146	Peroxisome	3/1047	89/7206	0.0011954860362
ko05140	Leishmaniasis	2/1047	75/7206	0.0013927260567
ko04750	Inflammatory mediator regulation of TRP channels	31/1047	122/7206	0.00161283892015
ko04964	Proximal tubule bicarbonate reclamation	11/1047	29/7206	0.00161589273611
ko05110	Vibrio cholerae infection	19/1047	63/7206	0.0016718105433
ko04976	Bile secretion	22/1047	80/7206	0.00214370633736
ko04626	Plant-pathogen interaction	8/1047	18/7206	0.00217791073025
ko04915	Estrogen signaling pathway	32/1047	131/7206	0.00242086807841
ko05414	Dilated cardiomyopathy	28/1047	112/7206	0.00279850399581
ko00280	Valine, leucine and isoleucine degradation	1/1047	54/7206	0.00323150385253
ko04540	Gap junction	31/1047	128/7206	0.00329538669835
ko04610	Complement and coagulation cascades	3/1047	79/7206	0.0034383640965
ko05162	Measles	7/1047	120/7206	0.0038650929743
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/1047	59/7206	0.00439330490699
ko00590	Arachidonic acid metabolism	1/1047	52/7206	0.00484694825245
ko04371	Apelin signaling pathway	39/1047	177/7206	0.00659992449505
ko04924	Renin secretion	22/1047	86/7206	0.00789235793021
ko05166	HTLV-I infection	27/1047	292/7206	0.00834373920856
ko05169	Epstein-Barr virus infection	17/1047	206/7206	0.00873642560015
ko00330	Arginine and proline metabolism	2/1047	61/7206	0.00926096165602
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1047	14/7206	0.00979916222453
ko03420	Nucleotide excision repair	1/1047	46/7206	0.0107141649854
ko05161	Hepatitis B	14/1047	173/7206	0.0119514839791
ko00240	Pyrimidine metabolism	7/1047	110/7206	0.0132433498244
ko05145	Toxoplasmosis	9/1047	126/7206	0.0149416804796
ko03022	Basal transcription factors	1/1047	44/7206	0.0161676866279
ko05144	Malaria	1/1047	45/7206	0.0168451046753
ko00071	Fatty acid degradation	1/1047	45/7206	0.0168451046753
ko00480	Glutathione metabolism	2/1047	55/7206	0.0191703776102
ko04640	Hematopoietic cell lineage	3/1047	64/7206	0.0199047031749
ko04115	p53 signaling pathway	4/1047	74/7206	0.0200292369777
ko00562	Inositol phosphate metabolism	21/1047	89/7206	0.0218976088549
ko04710	Circadian rhythm	12/1047	43/7206	0.0262197967613
ko05131	Shigellosis	5/1047	82/7206	0.0265923003771
ko04214	Apoptosis - fly	4/1047	72/7206	0.027761902305
ko00310	Lysine degradation	4/1047	73/7206	0.0282083824788
ko04330	Notch signaling pathway	3/1047	62/7206	0.0282246351742
ko04622	RIG-I-like receptor signaling pathway	3/1047	62/7206	0.0282246351742
ko04930	Type II diabetes mellitus	14/1047	54/7206	0.02997958894
ko04217	Necroptosis	16/1047	178/7206	0.0312257078398
ko04062	Chemokine signaling pathway	40/1047	201/7206	0.0328079334808
ko04923	Regulation of lipolysis in adipocytes	18/1047	77/7206	0.0337601827373
ko05217	Basal cell carcinoma	4/1047	68/7206	0.0380983062087
ko03320	PPAR signaling pathway	4/1047	69/7206	0.0381933676148
ko05219	Bladder cancer	2/1047	48/7206	0.0386776266418
ko05034	Alcoholism	46/1047	238/7206	0.0391146386766
ko04510	Focal adhesion	24/1047	240/7206	0.0406165419153
ko04658	Th1 and Th2 cell differentiation	7/1047	96/7206	0.0409766797372
ko04960	Aldosterone-regulated sodium reabsorption	11/1047	41/7206	0.041045081405
ko05410	Hypertrophic cardiomyopathy (HCM)	22/1047	100/7206	0.0438909876981
ko04630	Jak-STAT signaling pathway	11/1047	132/7206	0.0450829336087
ko04657	IL-17 signaling pathway	6/1047	87/7206	0.0451921577151
ko05133	Pertussis	6/1047	87/7206	0.0451921577151
ko04391	Hippo signaling pathway - fly	20/1047	90/7206	0.04868391272