ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	54/502	152/7206	2.44094709473e-25
ko04080	Neuroactive ligand-receptor interaction	84/502	423/7206	1.19480574033e-19
ko05032	Morphine addiction	38/502	110/7206	1.27219638734e-17
ko05033	Nicotine addiction	27/502	56/7206	3.24172192116e-17
ko04727	GABAergic synapse	37/502	110/7206	9.50473523699e-17
ko04723	Retrograde endocannabinoid signaling	46/502	175/7206	7.95421584649e-16
ko04713	Circadian entrainment	40/502	136/7206	1.02071664383e-15
ko04728	Dopaminergic synapse	46/502	185/7206	7.8560815689e-15
ko04725	Cholinergic synapse	36/502	160/7206	1.65123562083e-10
ko04911	Insulin secretion	30/502	117/7206	1.96317323796e-10
ko04020	Calcium signaling pathway	48/502	265/7206	4.58453877689e-10
ko04024	cAMP signaling pathway	49/502	279/7206	9.00944070086e-10
ko05031	Amphetamine addiction	25/502	91/7206	1.38298255324e-09
ko05030	Cocaine addiction	21/502	73/7206	1.19302198246e-08
ko04261	Adrenergic signaling in cardiomyocytes	37/502	205/7206	5.5243211328e-08
ko04742	Taste transduction	18/502	61/7206	8.68105899057e-08
ko04720	Long-term potentiation	23/502	99/7206	1.92731773743e-07
ko04010	MAPK signaling pathway	48/502	321/7206	4.11812631265e-07
ko04726	Serotonergic synapse	27/502	137/7206	6.03676072747e-07
ko04921	Oxytocin signaling pathway	35/502	209/7206	1.05615266834e-06
ko04072	Phospholipase D signaling pathway	32/502	197/7206	5.42249580025e-06
ko04721	Synaptic vesicle cycle	18/502	80/7206	6.75987501924e-06
ko04925	Aldosterone synthesis and secretion	21/502	105/7206	8.54345537029e-06
ko04915	Estrogen signaling pathway	23/502	131/7206	3.02377324625e-05
ko05203	Viral carcinogenesis	4/502	277/7206	3.06046687618e-05
ko05414	Dilated cardiomyopathy	20/502	112/7206	7.75027007067e-05
ko04970	Salivary secretion	18/502	95/7206	7.93033028723e-05
ko04740	Olfactory transduction	15/502	80/7206	0.00034776771496
ko00512	Mucin type O-glycan biosynthesis	8/502	29/7206	0.000608767727113
ko04744	Phototransduction	9/502	36/7206	0.000618824762401
ko04730	Long-term depression	14/502	78/7206	0.000858167119659
ko04972	Pancreatic secretion	18/502	111/7206	0.000908471652739
ko03013	RNA transport	2/502	166/7206	0.000974874683027
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/502	79/7206	0.00097807828536
ko04022	cGMP-PKG signaling pathway	28/502	216/7206	0.00150987590742
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/502	14/7206	0.0018989210455
ko04070	Phosphatidylinositol signaling system	17/502	112/7206	0.00207625217564
ko04514	Cell adhesion molecules (CAMs)	19/502	130/7206	0.00239780536683
ko05231	Choline metabolism in cancer	19/502	134/7206	0.00287584121737
ko04110	Cell cycle	2/502	145/7206	0.00427555027612
ko05014	Amyotrophic lateral sclerosis (ALS)	12/502	74/7206	0.00473015947241
ko00515	Mannose type O-glycan biosynthesis	6/502	25/7206	0.00627923212221
ko04144	Endocytosis	37/502	342/7206	0.00632053752383
ko05168	Herpes simplex infection	4/502	182/7206	0.00719012491756
ko04971	Gastric acid secretion	14/502	98/7206	0.00840766754514
ko00562	Inositol phosphate metabolism	13/502	89/7206	0.00981005657484
ko04912	GnRH signaling pathway	16/502	122/7206	0.0116370308881
ko05034	Alcoholism	27/502	238/7206	0.0129563945241
ko05205	Proteoglycans in cancer	9/502	271/7206	0.0142939097129
ko04145	Phagosome	4/502	162/7206	0.018318200522
ko04923	Regulation of lipolysis in adipocytes	11/502	77/7206	0.0207050477676
ko04540	Gap junction	16/502	128/7206	0.0209302651196
ko00513	Various types of N-glycan biosynthesis	7/502	42/7206	0.024491770404
ko05410	Hypertrophic cardiomyopathy (HCM)	13/502	100/7206	0.0268111935761
ko04750	Inflammatory mediator regulation of TRP channels	15/502	122/7206	0.0291753040781
ko04014	Ras signaling pathway	29/502	279/7206	0.0298242083274
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	5/502	26/7206	0.0312378412048
ko04062	Chemokine signaling pathway	22/502	201/7206	0.0336131288527
ko04670	Leukocyte transendothelial migration	4/502	151/7206	0.0340675890162
ko05322	Systemic lupus erythematosus	4/502	151/7206	0.0340675890162
ko00190	Oxidative phosphorylation	3/502	127/7206	0.0342652173706
ko04371	Apelin signaling pathway	20/502	177/7206	0.0343266065726
ko00240	Pyrimidine metabolism	2/502	110/7206	0.0346679897821
ko04630	Jak-STAT signaling pathway	3/502	132/7206	0.0356665329434
ko05202	Transcriptional misregulation in cancer	6/502	188/7206	0.0406152070325
ko00601	Glycosphingolipid biosynthesis - lacto and neolacto series	5/502	28/7206	0.0416605499219
ko03008	Ribosome biogenesis in eukaryotes	1/502	79/7206	0.0427943874569
ko04140	Autophagy - animal	5/502	164/7206	0.0431842364868
ko04068	FoxO signaling pathway	5/502	167/7206	0.0437156288315
ko04137	Mitophagy - animal	1/502	82/7206	0.0447506143678
ko04260	Cardiac muscle contraction	12/502	98/7206	0.045608858104
ko04360	Axon guidance	24/502	233/7206	0.0490033065585