ko pathway ratio_in_study ratio_in_pop p_value ko04710 Circadian rhythm 12/469 43/7206 1.20166529108e-05 ko04070 Phosphatidylinositol signaling system 18/469 112/7206 0.00029484416755 ko04745 Phototransduction - fly 9/469 38/7206 0.00057795888446 ko04922 Glucagon signaling pathway 19/469 128/7206 0.000737333714054 ko03040 Spliceosome 1/469 145/7206 0.00100822221036 ko03013 RNA transport 2/469 166/7206 0.00206772635047 ko04020 Calcium signaling pathway 30/469 265/7206 0.00312486829898 ko03010 Ribosome 1/469 129/7206 0.00322704774934 ko04713 Circadian entrainment 18/469 136/7206 0.00400409169626 ko04060 Cytokine-cytokine receptor interaction 23/469 191/7206 0.00410657504199 ko05322 Systemic lupus erythematosus 2/469 151/7206 0.00415334184861 ko01040 Biosynthesis of unsaturated fatty acids 6/469 25/7206 0.00450098493209 ko00051 Fructose and mannose metabolism 8/469 42/7206 0.00501794752563 ko04650 Natural killer cell mediated cytotoxicity 14/469 97/7206 0.00521817327408 ko05230 Central carbon metabolism in cancer 12/469 81/7206 0.00579927846696 ko04724 Glutamatergic synapse 19/469 152/7206 0.00665650734722 ko00120 Primary bile acid biosynthesis 5/469 20/7206 0.00782919755308 ko04711 Circadian rhythm - fly 4/469 13/7206 0.00789968671301 ko04137 Mitophagy - animal 12/469 82/7206 0.0102893979252 ko00140 Steroid hormone biosynthesis 7/469 41/7206 0.015423060678 ko05167 Kaposi's sarcoma-associated herpesvirus infection 21/469 191/7206 0.0164509388711 ko04380 Osteoclast differentiation 16/469 134/7206 0.0192430701806 ko04925 Aldosterone synthesis and secretion 13/469 105/7206 0.0250310610511 ko04110 Cell cycle 3/469 145/7206 0.0253795107935 ko04626 Plant-pathogen interaction 4/469 18/7206 0.0261125590169 ko00010 Glycolysis / Gluconeogenesis 10/469 74/7206 0.0275172989853 ko00592 alpha-Linolenic acid metabolism 4/469 19/7206 0.031423361031 ko04141 Protein processing in endoplasmic reticulum 5/469 184/7206 0.0328049422861 ko04022 cGMP-PKG signaling pathway 22/469 216/7206 0.0344057232049 ko04014 Ras signaling pathway 27/469 279/7206 0.0347451629867 ko04720 Long-term potentiation 12/469 99/7206 0.036177710036 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/469 5/7206 0.037055986699 ko00230 Purine metabolism 20/469 194/7206 0.0376488953148 ko04666 Fc gamma R-mediated phagocytosis 14/469 122/7206 0.0384239630141 ko04072 Phospholipase D signaling pathway 20/469 197/7206 0.0404309634005 ko04138 Autophagy - yeast 10/469 81/7206 0.0406031570475 ko05340 Primary immunodeficiency 5/469 30/7206 0.0422228887036 ko04921 Oxytocin signaling pathway 21/469 209/7206 0.0448476432201 ko00562 Inositol phosphate metabolism 11/469 89/7206 0.046401925082 ko04136 Autophagy - other 5/469 31/7206 0.0477576594648 ko05031 Amphetamine addiction 11/469 91/7206 0.0489285325796 ko04725 Cholinergic synapse 17/469 160/7206 0.0489705244806