ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	156/905	423/7206	2.27048582734e-40
ko04724	Glutamatergic synapse	81/905	152/7206	1.88827318919e-34
ko05033	Nicotine addiction	46/905	56/7206	1.31242171231e-32
ko04727	GABAergic synapse	60/905	110/7206	1.91112005221e-26
ko05032	Morphine addiction	59/905	110/7206	1.66920537233e-25
ko04713	Circadian entrainment	64/905	136/7206	1.85563743652e-23
ko04723	Retrograde endocannabinoid signaling	69/905	175/7206	7.77311190772e-20
ko04728	Dopaminergic synapse	70/905	185/7206	6.18445808646e-19
ko04725	Cholinergic synapse	64/905	160/7206	7.46830667775e-19
ko04744	Phototransduction	26/905	36/7206	1.97470463124e-16
ko04742	Taste transduction	33/905	61/7206	6.26000760601e-15
ko04020	Calcium signaling pathway	80/905	265/7206	7.97249227814e-15
ko04024	cAMP signaling pathway	82/905	279/7206	2.00046050329e-14
ko04726	Serotonergic synapse	51/905	137/7206	9.08932306861e-14
ko04911	Insulin secretion	46/905	117/7206	1.50198991407e-13
ko04721	Synaptic vesicle cycle	34/905	80/7206	1.82432482049e-11
ko04740	Olfactory transduction	33/905	80/7206	9.57744251646e-11
ko05031	Amphetamine addiction	34/905	91/7206	1.17609524433e-09
ko04921	Oxytocin signaling pathway	58/905	209/7206	1.97308177055e-09
ko04970	Salivary secretion	33/905	95/7206	1.72969610862e-08
ko04720	Long-term potentiation	33/905	99/7206	5.47058837823e-08
ko04261	Adrenergic signaling in cardiomyocytes	53/905	205/7206	1.49812859807e-07
ko03040	Spliceosome	1/905	145/7206	1.50516974623e-07
ko05030	Cocaine addiction	26/905	73/7206	3.24810179355e-07
ko04972	Pancreatic secretion	34/905	111/7206	3.48239659065e-07
ko04925	Aldosterone synthesis and secretion	32/905	105/7206	8.72675357807e-07
ko05203	Viral carcinogenesis	13/905	277/7206	1.11767587041e-05
ko04971	Gastric acid secretion	28/905	98/7206	1.81796139493e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	23/905	74/7206	2.10423507741e-05
ko03013	RNA transport	5/905	166/7206	2.48135027749e-05
ko05164	Influenza A	5/905	167/7206	2.5311559137e-05
ko05322	Systemic lupus erythematosus	4/905	151/7206	2.95122049422e-05
ko04120	Ubiquitin mediated proteolysis	4/905	138/7206	0.000127205349254
ko04010	MAPK signaling pathway	64/905	321/7206	0.000132930624899
ko04022	cGMP-PKG signaling pathway	47/905	216/7206	0.000144981906405
ko04730	Long-term depression	22/905	78/7206	0.000186999227373
ko04514	Cell adhesion molecules (CAMs)	31/905	130/7206	0.000402559530571
ko04711	Circadian rhythm - fly	7/905	13/7206	0.000415620645304
ko04964	Proximal tubule bicarbonate reclamation	11/905	29/7206	0.000463886935497
ko04745	Phototransduction - fly	13/905	38/7206	0.000467151328902
ko03008	Ribosome biogenesis in eukaryotes	1/905	79/7206	0.000488128723055
ko04750	Inflammatory mediator regulation of TRP channels	29/905	122/7206	0.000498047933251
ko04260	Cardiac muscle contraction	25/905	98/7206	0.000539507398735
ko05205	Proteoglycans in cancer	17/905	271/7206	0.000735771285635
ko05162	Measles	4/905	120/7206	0.000736164415513
ko05130	Pathogenic Escherichia coli infection	1/905	77/7206	0.000746550424467
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/905	79/7206	0.00083501338147
ko04110	Cell cycle	6/905	145/7206	0.000867124072625
ko04014	Ras signaling pathway	54/905	279/7206	0.000874834683329
ko04976	Bile secretion	21/905	80/7206	0.000909113054326
ko04072	Phospholipase D signaling pathway	41/905	197/7206	0.000960014670725
ko05168	Herpes simplex infection	10/905	182/7206	0.00207643549708
ko04141	Protein processing in endoplasmic reticulum	10/905	184/7206	0.0021268661153
ko04924	Renin secretion	21/905	86/7206	0.00259619971833
ko04930	Type II diabetes mellitus	15/905	54/7206	0.00272933037202
ko04540	Gap junction	28/905	128/7206	0.00277458825806
ko04621	NOD-like receptor signaling pathway	8/905	157/7206	0.00313716232228
ko05166	HTLV-I infection	21/905	292/7206	0.003746972255
ko04973	Carbohydrate digestion and absorption	12/905	42/7206	0.0043324824597
ko00330	Arginine and proline metabolism	1/905	61/7206	0.00543737807018
ko04146	Peroxisome	3/905	89/7206	0.00546820437182
ko04060	Cytokine-cytokine receptor interaction	12/905	191/7206	0.00552526823059
ko04710	Circadian rhythm	12/905	43/7206	0.00840011589878
ko05414	Dilated cardiomyopathy	24/905	112/7206	0.0087846458122
ko04070	Phosphatidylinositol signaling system	24/905	112/7206	0.0087846458122
ko04062	Chemokine signaling pathway	38/905	201/7206	0.00915306315844
ko05169	Epstein-Barr virus infection	14/905	206/7206	0.0100381292353
ko05161	Hepatitis B	11/905	173/7206	0.0102719200243
ko04145	Phagosome	10/905	162/7206	0.0112596942184
ko05016	Huntington's disease	15/905	215/7206	0.0116632068951
ko00520	Amino sugar and nucleotide sugar metabolism	1/905	55/7206	0.0121091387985
ko04960	Aldosterone-regulated sodium reabsorption	11/905	41/7206	0.0142951441145
ko04612	Antigen processing and presentation	3/905	77/7206	0.0151409619556
ko00230	Purine metabolism	36/905	194/7206	0.0151423249617
ko04610	Complement and coagulation cascades	3/905	79/7206	0.0154168070485
ko04218	Cellular senescence	12/905	177/7206	0.0156751664972
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/905	59/7206	0.0160498896224
ko00590	Arachidonic acid metabolism	1/905	52/7206	0.0180444316292
ko04974	Protein digestion and absorption	20/905	96/7206	0.0192895068419
ko05140	Leishmaniasis	3/905	75/7206	0.021395755295
ko05133	Pertussis	4/905	87/7206	0.0214863288594
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/905	182/7206	0.0231510119779
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/905	14/7206	0.0233503608211
ko05231	Choline metabolism in cancer	26/905	134/7206	0.0241104944939
ko00620	Pyruvate metabolism	1/905	46/7206	0.0251290847435
ko03420	Nucleotide excision repair	1/905	46/7206	0.0251290847435
ko00270	Cysteine and methionine metabolism	1/905	47/7206	0.0252551235421
ko04360	Axon guidance	41/905	233/7206	0.0263556041199
ko04371	Apelin signaling pathway	32/905	177/7206	0.0290001984952
ko04217	Necroptosis	13/905	178/7206	0.0294246319046
ko05224	Breast cancer	13/905	174/7206	0.0372695531336
ko03022	Basal transcription factors	1/905	44/7206	0.0372822743754
ko00071	Fatty acid degradation	1/905	45/7206	0.0382678234601
ko03015	mRNA surveillance pathway	5/905	93/7206	0.0387366533846
ko05200	Pathways in cancer	47/905	492/7206	0.0406290872543
ko05416	Viral myocarditis	2/905	55/7206	0.0407617368827
ko04150	mTOR signaling pathway	14/905	184/7206	0.0418057464773
ko03320	PPAR signaling pathway	3/905	69/7206	0.0421492102117
ko05215	Prostate cancer	7/905	111/7206	0.043088955691
ko04630	Jak-STAT signaling pathway	9/905	132/7206	0.0459333307145
ko04142	Lysosome	11/905	151/7206	0.0469398124802
ko04510	Focal adhesion	20/905	240/7206	0.0469992664048
ko04270	Vascular smooth muscle contraction	28/905	154/7206	0.0478897172817