ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	163/885	423/7206	1.34809965177e-46
ko04724	Glutamatergic synapse	71/885	152/7206	2.7560381513e-26
ko05033	Nicotine addiction	41/885	56/7206	5.18617784011e-26
ko04713	Circadian entrainment	62/885	136/7206	2.29574745833e-22
ko05032	Morphine addiction	50/885	110/7206	3.52908504945e-18
ko04020	Calcium signaling pathway	84/885	265/7206	1.49912199641e-17
ko04728	Dopaminergic synapse	67/885	185/7206	1.59627691369e-17
ko04727	GABAergic synapse	48/885	110/7206	1.29917635735e-16
ko04921	Oxytocin signaling pathway	70/885	209/7206	3.53342131845e-16
ko04911	Insulin secretion	46/885	117/7206	6.51518353472e-14
ko04725	Cholinergic synapse	55/885	160/7206	1.75326381775e-13
ko04024	cAMP signaling pathway	78/885	279/7206	5.2657456225e-13
ko04723	Retrograde endocannabinoid signaling	56/885	175/7206	3.06699724462e-12
ko05031	Amphetamine addiction	37/885	91/7206	5.85553813362e-12
ko04360	Axon guidance	67/885	233/7206	6.81123785613e-12
ko04721	Synaptic vesicle cycle	34/885	80/7206	9.6817427141e-12
ko04742	Taste transduction	29/885	61/7206	1.11775364052e-11
ko04261	Adrenergic signaling in cardiomyocytes	59/885	205/7206	1.50473623938e-10
ko04970	Salivary secretion	35/885	95/7206	5.63829885603e-10
ko04726	Serotonergic synapse	43/885	137/7206	2.13519269157e-09
ko04720	Long-term potentiation	33/885	99/7206	3.156238063e-08
ko04022	cGMP-PKG signaling pathway	56/885	216/7206	3.56199595922e-08
ko04010	MAPK signaling pathway	72/885	321/7206	1.93026694705e-07
ko03040	Spliceosome	1/885	145/7206	2.36784164269e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	26/885	74/7206	2.83290332928e-07
ko04971	Gastric acid secretion	30/885	98/7206	1.07185129448e-06
ko04514	Cell adhesion molecules (CAMs)	36/885	130/7206	2.04723418654e-06
ko05030	Cocaine addiction	24/885	73/7206	3.17031506358e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	25/885	79/7206	4.33639209577e-06
ko05203	Viral carcinogenesis	12/885	277/7206	5.95216297874e-06
ko05322	Systemic lupus erythematosus	3/885	151/7206	7.28179300829e-06
ko04730	Long-term depression	24/885	78/7206	1.15372266457e-05
ko04925	Aldosterone synthesis and secretion	29/885	105/7206	1.63652824649e-05
ko05168	Herpes simplex infection	6/885	182/7206	2.95562364261e-05
ko04120	Ubiquitin mediated proteolysis	3/885	138/7206	3.34956437978e-05
ko03013	RNA transport	5/885	166/7206	3.62171789813e-05
ko05164	Influenza A	5/885	167/7206	3.67352210435e-05
ko04972	Pancreatic secretion	29/885	111/7206	5.5212443758e-05
ko04141	Protein processing in endoplasmic reticulum	7/885	184/7206	9.10985998619e-05
ko04621	NOD-like receptor signaling pathway	5/885	157/7206	0.000106519994263
ko04014	Ras signaling pathway	56/885	279/7206	0.000172717635679
ko05414	Dilated cardiomyopathy	28/885	112/7206	0.000201732486285
ko04260	Cardiac muscle contraction	25/885	98/7206	0.000271849672741
ko05410	Hypertrophic cardiomyopathy (HCM)	25/885	100/7206	0.000543412275171
ko04924	Renin secretion	22/885	86/7206	0.000683061831074
ko04612	Antigen processing and presentation	1/885	77/7206	0.000740296264851
ko03008	Ribosome biogenesis in eukaryotes	1/885	79/7206	0.00076759080084
ko04740	Olfactory transduction	21/885	80/7206	0.000807019749128
ko04371	Apelin signaling pathway	37/885	177/7206	0.00102928965722
ko05162	Measles	4/885	120/7206	0.00106824907768
ko04060	Cytokine-cytokine receptor interaction	10/885	191/7206	0.00159244429238
ko04146	Peroxisome	2/885	89/7206	0.00160762696862
ko04750	Inflammatory mediator regulation of TRP channels	27/885	122/7206	0.00194656125417
ko04540	Gap junction	28/885	128/7206	0.00241615338425
ko05169	Epstein-Barr virus infection	12/885	206/7206	0.00247072627958
ko04015	Rap1 signaling pathway	51/885	278/7206	0.00274867619453
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/885	182/7206	0.00280456847842
ko05016	Huntington's disease	13/885	215/7206	0.00300928816731
ko04626	Plant-pathogen interaction	7/885	18/7206	0.00384351150054
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/885	14/7206	0.00422659543639
ko04745	Phototransduction - fly	11/885	38/7206	0.0046882045051
ko04610	Complement and coagulation cascades	2/885	79/7206	0.00490778436921
ko00330	Arginine and proline metabolism	1/885	61/7206	0.00535425824672
ko04070	Phosphatidylinositol signaling system	24/885	112/7206	0.00539500002501
ko04964	Proximal tubule bicarbonate reclamation	9/885	29/7206	0.00621514810466
ko01524	Platinum drug resistance	2/885	76/7206	0.00717741988566
ko00240	Pyrimidine metabolism	5/885	110/7206	0.00823217635271
ko04976	Bile secretion	18/885	80/7206	0.00922893430159
ko04214	Apoptosis - fly	2/885	72/7206	0.0101125797561
ko05205	Proteoglycans in cancer	20/885	271/7206	0.0106065860078
ko04064	NF-kappa B signaling pathway	4/885	96/7206	0.0113694759561
ko00480	Glutathione metabolism	1/885	55/7206	0.0117952513042
ko04114	Oocyte meiosis	27/885	139/7206	0.0129751878346
ko04711	Circadian rhythm - fly	5/885	13/7206	0.015235525017
ko04930	Type II diabetes mellitus	13/885	54/7206	0.0189770160929
ko04916	Melanogenesis	27/885	142/7206	0.0193004951676
ko00260	Glycine, serine and threonine metabolism	1/885	48/7206	0.025454183282
ko05215	Prostate cancer	6/885	111/7206	0.0273452763832
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/885	59/7206	0.0283848096772
ko00564	Glycerophospholipid metabolism	5/885	99/7206	0.029146456077
ko04140	Autophagy - animal	11/885	164/7206	0.029323185506
ko04922	Glucagon signaling pathway	24/885	128/7206	0.0294788391148
ko00310	Lysine degradation	3/885	73/7206	0.0300682978137
ko04630	Jak-STAT signaling pathway	8/885	132/7206	0.0308927009143
ko04142	Lysosome	10/885	151/7206	0.0323285624316
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	7/885	26/7206	0.0331462803239
ko04270	Vascular smooth muscle contraction	28/885	154/7206	0.0337078662869
ko05161	Hepatitis B	12/885	173/7206	0.0337679446083
ko04710	Circadian rhythm	10/885	43/7206	0.03580017721
ko04217	Necroptosis	13/885	178/7206	0.0375110409472
ko00071	Fatty acid degradation	1/885	45/7206	0.0375735906941
ko03420	Nucleotide excision repair	1/885	46/7206	0.0385396241711
ko01200	Carbon metabolism	8/885	128/7206	0.0400843882727