ko pathway ratio_in_study ratio_in_pop p_value ko04724 Glutamatergic synapse 29/199 152/7206 5.34078421196e-17 ko04713 Circadian entrainment 26/199 136/7206 2.38356594735e-15 ko04728 Dopaminergic synapse 28/199 185/7206 9.36309541657e-14 ko05014 Amyotrophic lateral sclerosis (ALS) 17/199 74/7206 9.19002675218e-12 ko05031 Amphetamine addiction 17/199 91/7206 3.04572454782e-10 ko04911 Insulin secretion 19/199 117/7206 3.29688803389e-10 ko05033 Nicotine addiction 13/199 56/7206 2.4459754133e-09 ko04720 Long-term potentiation 16/199 99/7206 9.43371455596e-09 ko04721 Synaptic vesicle cycle 14/199 80/7206 2.88451122276e-08 ko04727 GABAergic synapse 16/199 110/7206 4.45800586261e-08 ko04725 Cholinergic synapse 19/199 160/7206 6.85163728253e-08 ko04024 cAMP signaling pathway 25/199 279/7206 1.58632553192e-07 ko04261 Adrenergic signaling in cardiomyocytes 21/199 205/7206 1.79604102282e-07 ko04080 Neuroactive ligand-receptor interaction 30/199 423/7206 1.41914157413e-06 ko04970 Salivary secretion 13/199 95/7206 1.75159843204e-06 ko05030 Cocaine addiction 11/199 73/7206 4.30033022159e-06 ko04514 Cell adhesion molecules (CAMs) 14/199 130/7206 1.24026544685e-05 ko04723 Retrograde endocannabinoid signaling 16/199 175/7206 2.39512261059e-05 ko04745 Phototransduction - fly 7/199 38/7206 6.72237922077e-05 ko04971 Gastric acid secretion 11/199 98/7206 7.4094791085e-05 ko05034 Alcoholism 18/199 238/7206 9.38233649834e-05 ko04726 Serotonergic synapse 13/199 137/7206 9.6886838665e-05 ko04626 Plant-pathogen interaction 5/199 18/7206 9.76152210941e-05 ko04924 Renin secretion 10/199 86/7206 0.000117201315063 ko05032 Morphine addiction 11/199 110/7206 0.00021121422794 ko04360 Axon guidance 17/199 233/7206 0.000227648998231 ko04730 Long-term depression 9/199 78/7206 0.000273417933251 ko04114 Oocyte meiosis 12/199 139/7206 0.000435249442833 ko04966 Collecting duct acid secretion 5/199 26/7206 0.000626016116649 ko04921 Oxytocin signaling pathway 15/199 209/7206 0.000635312497152 ko04022 cGMP-PKG signaling pathway 15/199 216/7206 0.000893799059861 ko05120 Epithelial cell signaling in Helicobacter pylori infection 9/199 92/7206 0.000934110399687 ko04964 Proximal tubule bicarbonate reclamation 5/199 29/7206 0.00105666589984 ko04961 Endocrine and other factor-regulated calcium reabsorption 7/199 59/7206 0.00111346812227 ko05010 Alzheimer's disease 14/199 202/7206 0.00134840415877 ko04740 Olfactory transduction 8/199 80/7206 0.00155083304692 ko05110 Vibrio cholerae infection 7/199 63/7206 0.00164562823662 ko04940 Type I diabetes mellitus 5/199 32/7206 0.00167549527648 ko04145 Phagosome 12/199 162/7206 0.00168689132408 ko04972 Pancreatic secretion 9/199 111/7206 0.00346614490235 ko04978 Mineral absorption 5/199 40/7206 0.00458048938174 ko04014 Ras signaling pathway 16/199 279/7206 0.00470444430395 ko04960 Aldosterone-regulated sodium reabsorption 5/199 41/7206 0.00510200212657 ko05152 Tuberculosis 12/199 187/7206 0.0054844618369 ko04260 Cardiac muscle contraction 8/199 98/7206 0.00552443144263 ko04973 Carbohydrate digestion and absorption 5/199 42/7206 0.00566424757313 ko05167 Kaposi's sarcoma-associated herpesvirus infection 12/199 191/7206 0.00647397516926 ko04020 Calcium signaling pathway 15/199 265/7206 0.00695207030787 ko04010 MAPK signaling pathway 17/199 321/7206 0.00841593373338 ko04922 Glucagon signaling pathway 9/199 128/7206 0.00876258163845 ko04015 Rap1 signaling pathway 15/199 278/7206 0.0131054538771 ko04916 Melanogenesis 9/199 142/7206 0.0165342327699 ko04310 Wnt signaling pathway 11/199 181/7206 0.017269919986 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/199 1/7206 0.0276158756591 ko04371 Apelin signaling pathway 10/199 177/7206 0.0310741301577 ko04918 Thyroid hormone synthesis 6/199 86/7206 0.0311591601427 ko04662 B cell receptor signaling pathway 6/199 88/7206 0.0343465654762 ko05323 Rheumatoid arthritis 6/199 89/7206 0.0360165158161 ko04151 PI3K-Akt signaling pathway 18/199 390/7206 0.0364381516097 ko04722 Neurotrophin signaling pathway 9/199 160/7206 0.0435300977763