ko pathway ratio_in_study ratio_in_pop p_value ko04710 Circadian rhythm 11/306 43/7206 1.15195641111e-06 ko04070 Phosphatidylinositol signaling system 17/306 112/7206 4.18892071548e-06 ko04921 Oxytocin signaling pathway 24/306 209/7206 7.55637746126e-06 ko05032 Morphine addiction 15/306 110/7206 5.67171549741e-05 ko04713 Circadian entrainment 17/306 136/7206 5.69539021723e-05 ko04020 Calcium signaling pathway 26/306 265/7206 6.03460464905e-05 ko04925 Aldosterone synthesis and secretion 14/306 105/7206 0.000128208353781 ko04725 Cholinergic synapse 18/306 160/7206 0.000138950241765 ko04724 Glutamatergic synapse 17/306 152/7206 0.000228252259014 ko04726 Serotonergic synapse 15/306 137/7206 0.000664576565221 ko04727 GABAergic synapse 13/306 110/7206 0.000732404027486 ko02010 ABC transporters 7/306 39/7206 0.00110708967797 ko05031 Amphetamine addiction 11/306 91/7206 0.00153822096029 ko04740 Olfactory transduction 10/306 80/7206 0.00193384779052 ko04728 Dopaminergic synapse 17/306 185/7206 0.00244229810332 ko04720 Long-term potentiation 11/306 99/7206 0.00303315049306 ko04744 Phototransduction 6/306 36/7206 0.00370091326868 ko04911 Insulin secretion 12/306 117/7206 0.00389834510984 ko00562 Inositol phosphate metabolism 10/306 89/7206 0.00426918925141 ko04745 Phototransduction - fly 6/306 38/7206 0.00488563369446 ko04626 Plant-pathogen interaction 4/306 18/7206 0.0060823107709 ko04970 Salivary secretion 10/306 95/7206 0.00678699614422 ko04930 Type II diabetes mellitus 7/306 54/7206 0.00740754142217 ko00051 Fructose and mannose metabolism 6/306 42/7206 0.00805668361302 ko00471 D-Glutamine and D-glutamate metabolism 2/306 4/7206 0.0101883198475 ko03013 RNA transport 1/306 166/7206 0.0103483738978 ko04072 Phospholipase D signaling pathway 16/306 197/7206 0.0111435967705 ko04922 Glucagon signaling pathway 12/306 128/7206 0.011658116177 ko04514 Cell adhesion molecules (CAMs) 12/306 130/7206 0.0123586086303 ko00010 Glycolysis / Gluconeogenesis 8/306 74/7206 0.0127218511725 ko00680 Methane metabolism 5/306 34/7206 0.013510602644 ko05203 Viral carcinogenesis 4/306 277/7206 0.0140811814824 ko04010 MAPK signaling pathway 23/306 321/7206 0.0148305461853 ko04145 Phagosome 1/306 162/7206 0.0156070443608 ko04711 Circadian rhythm - fly 3/306 13/7206 0.0157933616166 ko04750 Inflammatory mediator regulation of TRP channels 11/306 122/7206 0.0190905164706 ko00604 Glycosphingolipid biosynthesis - ganglio series 3/306 14/7206 0.0194800308431 ko04261 Adrenergic signaling in cardiomyocytes 16/306 205/7206 0.0199538614228 ko04723 Retrograde endocannabinoid signaling 14/306 175/7206 0.0206614685799 ko05230 Central carbon metabolism in cancer 8/306 81/7206 0.021068507517 ko04024 cAMP signaling pathway 20/306 279/7206 0.0215582673415 ko03040 Spliceosome 1/306 145/7206 0.0215998294958 ko04022 cGMP-PKG signaling pathway 16/306 216/7206 0.0254993396104 ko04152 AMPK signaling pathway 13/306 161/7206 0.026239003859 ko04360 Axon guidance 17/306 233/7206 0.0295047676626 ko04964 Proximal tubule bicarbonate reclamation 4/306 29/7206 0.0327761249198 ko04971 Gastric acid secretion 9/306 98/7206 0.0367044098838 ko00901 Indole alkaloid biosynthesis 1/306 1/7206 0.0424646128226 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/306 1/7206 0.0424646128226 ko03010 Ribosome 1/306 129/7206 0.0449355222735 ko00030 Pentose phosphate pathway 4/306 32/7206 0.0449756792371 ko00230 Purine metabolism 14/306 194/7206 0.045750441636 ko04722 Neurotrophin signaling pathway 12/306 160/7206 0.0465684902317 ko04014 Ras signaling pathway 19/306 279/7206 0.0465727406512 ko05164 Influenza A 2/306 167/7206 0.0493145134072