ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	126/828	423/7206	3.96673778748e-26
ko05033	Nicotine addiction	40/828	56/7206	7.50585597066e-26
ko04724	Glutamatergic synapse	67/828	152/7206	9.41369040997e-25
ko04728	Dopaminergic synapse	73/828	185/7206	2.58305896427e-23
ko05032	Morphine addiction	53/828	110/7206	5.17536549537e-22
ko04727	GABAergic synapse	52/828	110/7206	3.87398025004e-21
ko04713	Circadian entrainment	56/828	136/7206	3.89485241051e-19
ko04744	Phototransduction	27/828	36/7206	9.84159028348e-19
ko04024	cAMP signaling pathway	83/828	279/7206	2.76384385844e-17
ko04725	Cholinergic synapse	58/828	160/7206	1.11282181607e-16
ko04723	Retrograde endocannabinoid signaling	61/828	175/7206	1.53804134294e-16
ko04721	Synaptic vesicle cycle	38/828	80/7206	7.49835446913e-16
ko04020	Calcium signaling pathway	71/828	265/7206	2.19607885368e-12
ko05031	Amphetamine addiction	36/828	91/7206	4.10163691201e-12
ko04726	Serotonergic synapse	46/828	137/7206	4.26722591264e-12
ko04921	Oxytocin signaling pathway	60/828	209/7206	4.91475765734e-12
ko04911	Insulin secretion	40/828	117/7206	5.84864497812e-11
ko04720	Long-term potentiation	36/828	99/7206	7.28980272132e-11
ko04261	Adrenergic signaling in cardiomyocytes	57/828	205/7206	7.91076573648e-11
ko04742	Taste transduction	23/828	61/7206	9.38205016532e-08
ko04010	MAPK signaling pathway	69/828	321/7206	1.37810544297e-07
ko05030	Cocaine addiction	25/828	73/7206	2.32449049478e-07
ko04060	Cytokine-cytokine receptor interaction	3/828	191/7206	3.80196664905e-07
ko04745	Phototransduction - fly	16/828	38/7206	1.53649252016e-06
ko04070	Phosphatidylinositol signaling system	31/828	112/7206	2.87608980686e-06
ko05322	Systemic lupus erythematosus	2/828	151/7206	3.53089936556e-06
ko04730	Long-term depression	24/828	78/7206	3.6091017384e-06
ko03010	Ribosome	1/828	129/7206	4.26646206323e-06
ko04970	Salivary secretion	27/828	95/7206	4.91677857392e-06
ko04740	Olfactory transduction	24/828	80/7206	5.90871806248e-06
ko03040	Spliceosome	2/828	145/7206	8.06305100666e-06
ko05203	Viral carcinogenesis	11/828	277/7206	1.19675520005e-05
ko04925	Aldosterone synthesis and secretion	28/828	105/7206	1.50321291638e-05
ko04022	cGMP-PKG signaling pathway	46/828	216/7206	2.88581692916e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	21/828	74/7206	5.63181081721e-05
ko04260	Cardiac muscle contraction	25/828	98/7206	8.66283598669e-05
ko04014	Ras signaling pathway	54/828	279/7206	0.000108534523247
ko03013	RNA transport	5/828	166/7206	0.000110655147894
ko04072	Phospholipase D signaling pathway	41/828	197/7206	0.000148342346141
ko04110	Cell cycle	4/828	145/7206	0.000191832634985
ko04971	Gastric acid secretion	24/828	98/7206	0.000301717566762
ko04966	Collecting duct acid secretion	10/828	26/7206	0.000359037926301
ko05168	Herpes simplex infection	7/828	182/7206	0.000359458492894
ko04626	Plant-pathogen interaction	8/828	18/7206	0.000446700162422
ko05169	Epstein-Barr virus infection	9/828	206/7206	0.000513647028891
ko04514	Cell adhesion molecules (CAMs)	28/828	130/7206	0.000783812264812
ko04621	NOD-like receptor signaling pathway	6/828	157/7206	0.000914957765168
ko04610	Complement and coagulation cascades	1/828	79/7206	0.00115298854356
ko05164	Influenza A	7/828	167/7206	0.00128932266589
ko04922	Glucagon signaling pathway	27/828	128/7206	0.0017607414559
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/828	79/7206	0.00192436620379
ko05110	Vibrio cholerae infection	16/828	63/7206	0.00202770832704
ko04915	Estrogen signaling pathway	27/828	131/7206	0.002121281521
ko05162	Measles	4/828	120/7206	0.00219853242405
ko04972	Pancreatic secretion	24/828	111/7206	0.00224184301163
ko04710	Circadian rhythm	12/828	43/7206	0.00254744500377
ko04350	TGF-beta signaling pathway	3/828	103/7206	0.00279371127265
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/828	14/7206	0.00300426805403
ko04360	Axon guidance	42/828	233/7206	0.00320872949312
ko04750	Inflammatory mediator regulation of TRP channels	25/828	122/7206	0.00369813039784
ko04964	Proximal tubule bicarbonate reclamation	9/828	29/7206	0.00397448535906
ko05230	Central carbon metabolism in cancer	18/828	81/7206	0.00468332492922
ko05166	HTLV-I infection	19/828	292/7206	0.00480166262046
ko05034	Alcoholism	42/828	238/7206	0.0049472351491
ko04924	Renin secretion	19/828	86/7206	0.00543916010595
ko04064	NF-kappa B signaling pathway	3/828	96/7206	0.0056304779029
ko04722	Neurotrophin signaling pathway	30/828	160/7206	0.00565022395527
ko04120	Ubiquitin mediated proteolysis	6/828	138/7206	0.00637803374543
ko00562	Inositol phosphate metabolism	19/828	89/7206	0.00663038695417
ko04141	Protein processing in endoplasmic reticulum	10/828	184/7206	0.00674626458236
ko04930	Type II diabetes mellitus	13/828	54/7206	0.00823115509297
ko05140	Leishmaniasis	2/828	75/7206	0.0101237460982
ko05214	Glioma	17/828	79/7206	0.0112978605477
ko00680	Methane metabolism	9/828	34/7206	0.0123214060171
ko04012	ErbB signaling pathway	21/828	109/7206	0.01490626669
ko04371	Apelin signaling pathway	31/828	177/7206	0.0162764766489
ko00280	Valine, leucine and isoleucine degradation	1/828	54/7206	0.0176844184956
ko00480	Glutathione metabolism	1/828	55/7206	0.0178022327783
ko05120	Epithelial cell signaling in Helicobacter pylori infection	18/828	92/7206	0.0204238744038
ko05217	Basal cell carcinoma	2/828	68/7206	0.0207572691723
ko04960	Aldosterone-regulated sodium reabsorption	10/828	41/7206	0.0219891274105
ko04973	Carbohydrate digestion and absorption	10/828	42/7206	0.0240179520469
ko05010	Alzheimer's disease	34/828	202/7206	0.0243569723882
ko04071	Sphingolipid signaling pathway	28/828	162/7206	0.0244469521442
ko04540	Gap junction	23/828	128/7206	0.0251081828262
ko00010	Glycolysis / Gluconeogenesis	15/828	74/7206	0.025940999812
ko04630	Jak-STAT signaling pathway	7/828	132/7206	0.0261660055059
ko05231	Choline metabolism in cancer	24/828	134/7206	0.0273713635461
ko04640	Hematopoietic cell lineage	2/828	64/7206	0.0295280982723
ko05161	Hepatitis B	11/828	173/7206	0.0295596349083
ko04510	Focal adhesion	17/828	240/7206	0.0300232485482
ko05130	Pathogenic Escherichia coli infection	3/828	77/7206	0.0306049101809
ko04657	IL-17 signaling pathway	4/828	87/7206	0.041331333884
ko00512	Mucin type O-glycan biosynthesis	7/828	29/7206	0.0419217907114
ko04146	Peroxisome	4/828	89/7206	0.0423679071574
ko04114	Oocyte meiosis	24/828	139/7206	0.0424376842138
ko04115	p53 signaling pathway	3/828	74/7206	0.0425744217054
ko04330	Notch signaling pathway	2/828	62/7206	0.0426474990519
ko04550	Signaling pathways regulating pluripotency of stem cells	11/828	165/7206	0.04806288198
ko00240	Pyrimidine metabolism	6/828	110/7206	0.0486760642892