ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	165/1126	423/7206	1.33400145505e-33
ko04724	Glutamatergic synapse	70/1126	152/7206	3.05854066524e-19
ko05033	Nicotine addiction	36/1126	56/7206	1.88671489056e-16
ko04713	Circadian entrainment	59/1126	136/7206	6.3223309526e-15
ko04020	Calcium signaling pathway	89/1126	265/7206	1.56679097387e-13
ko04727	GABAergic synapse	49/1126	110/7206	3.85429032758e-13
ko05032	Morphine addiction	49/1126	110/7206	3.85429032758e-13
ko04721	Synaptic vesicle cycle	40/1126	80/7206	5.58833817143e-13
ko04723	Retrograde endocannabinoid signaling	63/1126	175/7206	2.17248614864e-11
ko04725	Cholinergic synapse	59/1126	160/7206	2.81621764031e-11
ko04728	Dopaminergic synapse	65/1126	185/7206	4.02265394633e-11
ko04024	cAMP signaling pathway	84/1126	279/7206	6.48529379021e-10
ko04921	Oxytocin signaling pathway	66/1126	209/7206	5.08277077508e-09
ko04726	Serotonergic synapse	49/1126	137/7206	6.0579712202e-09
ko05031	Amphetamine addiction	37/1126	91/7206	6.74168901196e-09
ko03010	Ribosome	1/1126	129/7206	1.08059272109e-08
ko05322	Systemic lupus erythematosus	3/1126	151/7206	4.26739998485e-08
ko04911	Insulin secretion	42/1126	117/7206	5.21376730841e-08
ko03040	Spliceosome	3/1126	145/7206	9.44523151862e-08
ko04742	Taste transduction	26/1126	61/7206	3.97168916666e-07
ko04970	Salivary secretion	34/1126	95/7206	1.10955013359e-06
ko03013	RNA transport	6/1126	166/7206	1.19885375372e-06
ko04925	Aldosterone synthesis and secretion	36/1126	105/7206	1.93933735727e-06
ko04720	Long-term potentiation	34/1126	99/7206	3.86265953098e-06
ko04966	Collecting duct acid secretion	14/1126	26/7206	7.24443173596e-06
ko00120	Primary bile acid biosynthesis	12/1126	20/7206	7.42618450917e-06
ko05030	Cocaine addiction	27/1126	73/7206	1.03037405919e-05
ko04110	Cell cycle	6/1126	145/7206	2.26746529271e-05
ko04971	Gastric acid secretion	32/1126	98/7206	2.89021912035e-05
ko05203	Viral carcinogenesis	20/1126	277/7206	3.02975415103e-05
ko04744	Phototransduction	16/1126	36/7206	3.7129095125e-05
ko04261	Adrenergic signaling in cardiomyocytes	54/1126	205/7206	5.59960779318e-05
ko04745	Phototransduction - fly	16/1126	38/7206	8.28753062228e-05
ko04710	Circadian rhythm	17/1126	43/7206	0.000128452310635
ko04022	cGMP-PKG signaling pathway	55/1126	216/7206	0.000179089324342
ko04120	Ubiquitin mediated proteolysis	7/1126	138/7206	0.000197494425872
ko05168	Herpes simplex infection	12/1126	182/7206	0.000267465135797
ko04972	Pancreatic secretion	32/1126	111/7206	0.000328242242577
ko05110	Vibrio cholerae infection	21/1126	63/7206	0.000390268739523
ko05169	Epstein-Barr virus infection	15/1126	206/7206	0.000412670227036
ko05164	Influenza A	11/1126	167/7206	0.000509047974396
ko04924	Renin secretion	26/1126	86/7206	0.000512736251276
ko04070	Phosphatidylinositol signaling system	32/1126	112/7206	0.000522481243583
ko04730	Long-term depression	24/1126	78/7206	0.000754670412497
ko05014	Amyotrophic lateral sclerosis (ALS)	23/1126	74/7206	0.000970771531033
ko05205	Proteoglycans in cancer	24/1126	271/7206	0.00113828928433
ko05166	HTLV-I infection	27/1126	292/7206	0.00168044791521
ko04750	Inflammatory mediator regulation of TRP channels	32/1126	122/7206	0.00230596710258
ko04260	Cardiac muscle contraction	27/1126	98/7206	0.0028279666869
ko04141	Protein processing in endoplasmic reticulum	15/1126	184/7206	0.00374307488434
ko05161	Hepatitis B	14/1126	173/7206	0.00406107614383
ko04371	Apelin signaling pathway	42/1126	177/7206	0.00440762732601
ko05219	Bladder cancer	1/1126	48/7206	0.00457468505124
ko05162	Measles	8/1126	120/7206	0.00486612991772
ko04014	Ras signaling pathway	61/1126	279/7206	0.00532621781681
ko04540	Gap junction	32/1126	128/7206	0.00637203998449
ko04270	Vascular smooth muscle contraction	37/1126	154/7206	0.0066644419339
ko00362	Benzoate degradation	4/1126	6/7206	0.00682737775543
ko05144	Malaria	1/1126	45/7206	0.00685274606078
ko03420	Nucleotide excision repair	1/1126	46/7206	0.00691607211977
ko04072	Phospholipase D signaling pathway	45/1126	197/7206	0.00696190168604
ko05133	Pertussis	5/1126	87/7206	0.00715484359012
ko04010	MAPK signaling pathway	68/1126	321/7206	0.00730519630851
ko04630	Jak-STAT signaling pathway	10/1126	132/7206	0.00754612646054
ko00520	Amino sugar and nucleotide sugar metabolism	2/1126	55/7206	0.00856801968263
ko05416	Viral myocarditis	2/1126	55/7206	0.00856801968263
ko04550	Signaling pathways regulating pluripotency of stem cells	14/1126	165/7206	0.00891617400617
ko04350	TGF-beta signaling pathway	7/1126	103/7206	0.00924394108174
ko04922	Glucagon signaling pathway	31/1126	128/7206	0.00965982069907
ko05220	Chronic myeloid leukemia	5/1126	85/7206	0.00994956672096
ko04011	MAPK signaling pathway - yeast	2/1126	53/7206	0.0124860789917
ko00350	Tyrosine metabolism	11/1126	33/7206	0.0126897227571
ko00643	Styrene degradation	3/1126	4/7206	0.0134465286108
ko02010	ABC transporters	12/1126	39/7206	0.0143377793743
ko04626	Plant-pathogen interaction	7/1126	18/7206	0.0145930264026
ko05224	Breast cancer	16/1126	174/7206	0.0150455838896
ko04623	Cytosolic DNA-sensing pathway	1/1126	41/7206	0.015552958854
ko04113	Meiosis - yeast	4/1126	70/7206	0.0194102117315
ko04810	Regulation of actin cytoskeleton	28/1126	264/7206	0.0197486246927
ko05211	Renal cell carcinoma	7/1126	96/7206	0.0226237579933
ko03410	Base excision repair	1/1126	38/7206	0.0229380449342
ko00010	Glycolysis / Gluconeogenesis	19/1126	74/7206	0.0232288912159
ko05130	Pathogenic Escherichia coli infection	5/1126	77/7206	0.0258906018942
ko04514	Cell adhesion molecules (CAMs)	30/1126	130/7206	0.0272108192298
ko04740	Olfactory transduction	20/1126	80/7206	0.0287446374069
ko05200	Pathways in cancer	60/1126	492/7206	0.028768304761
ko03015	mRNA surveillance pathway	7/1126	93/7206	0.0301077315299
ko04390	Hippo signaling pathway	19/1126	188/7206	0.0325853435505
ko00680	Methane metabolism	10/1126	34/7206	0.0337472541934
ko04964	Proximal tubule bicarbonate reclamation	9/1126	29/7206	0.0353875105529
ko04510	Focal adhesion	26/1126	240/7206	0.0373762676926
ko00360	Phenylalanine metabolism	6/1126	17/7206	0.0379745739818
ko04711	Circadian rhythm - fly	5/1126	13/7206	0.0398788464836
ko04111	Cell cycle - yeast	7/1126	90/7206	0.0398981213555
ko05206	MicroRNAs in cancer	18/1126	177/7206	0.0458290492041
ko04214	Apoptosis - fly	5/1126	72/7206	0.0482302257951
ko00190	Oxidative phosphorylation	28/1126	127/7206	0.0486304363843