ko pathway ratio_in_study ratio_in_pop p_value ko04724 Glutamatergic synapse 23/201 152/7206 2.22759043399e-11 ko04728 Dopaminergic synapse 21/201 185/7206 3.57695268199e-08 ko04514 Cell adhesion molecules (CAMs) 16/201 130/7206 5.46455613348e-07 ko04261 Adrenergic signaling in cardiomyocytes 20/201 205/7206 9.26584357764e-07 ko04720 Long-term potentiation 13/201 99/7206 3.15003760566e-06 ko04024 cAMP signaling pathway 22/201 279/7206 9.14358441192e-06 ko04911 Insulin secretion 13/201 117/7206 2.02733531541e-05 ko05031 Amphetamine addiction 11/201 91/7206 4.06233633828e-05 ko04721 Synaptic vesicle cycle 10/201 80/7206 6.84719419221e-05 ko00512 Mucin type O-glycan biosynthesis 6/201 29/7206 0.000121429429287 ko05033 Nicotine addiction 8/201 56/7206 0.000143364165508 ko05030 Cocaine addiction 9/201 73/7206 0.000176833715849 ko05014 Amyotrophic lateral sclerosis (ALS) 9/201 74/7206 0.000196533914553 ko04970 Salivary secretion 10/201 95/7206 0.000292270965157 ko04020 Calcium signaling pathway 18/201 265/7206 0.000406979348683 ko04713 Circadian entrainment 11/201 136/7206 0.00140093812681 ko04022 cGMP-PKG signaling pathway 14/201 216/7206 0.00277613526811 ko04723 Retrograde endocannabinoid signaling 12/201 175/7206 0.00349063412419 ko04010 MAPK signaling pathway 18/201 321/7206 0.00457445469347 ko04962 Vasopressin-regulated water reabsorption 6/201 58/7206 0.00529265735404 ko04742 Taste transduction 6/201 61/7206 0.00677797669156 ko05213 Endometrial cancer 6/201 62/7206 0.00733426082043 ko05203 Viral carcinogenesis 1/201 277/7206 0.00761555319941 ko04921 Oxytocin signaling pathway 13/201 209/7206 0.00799345554577 ko04925 Aldosterone synthesis and secretion 8/201 105/7206 0.00880782578484 ko04012 ErbB signaling pathway 8/201 109/7206 0.0109244690544 ko04727 GABAergic synapse 8/201 110/7206 0.0115078917345 ko00562 Inositol phosphate metabolism 7/201 89/7206 0.0118379582008 ko04972 Pancreatic secretion 8/201 111/7206 0.0121140179041 ko04072 Phospholipase D signaling pathway 12/201 197/7206 0.0123802197686 ko04070 Phosphatidylinositol signaling system 8/201 112/7206 0.0127433432593 ko04722 Neurotrophin signaling pathway 10/201 160/7206 0.0137988724404 ko05120 Epithelial cell signaling in Helicobacter pylori infection 7/201 92/7206 0.0140405173297 ko04260 Cardiac muscle contraction 7/201 98/7206 0.0193001609229 ko04080 Neuroactive ligand-receptor interaction 20/201 423/7206 0.0208131527188 ko04730 Long-term depression 6/201 78/7206 0.0212788328108 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 6/201 79/7206 0.022511355659 ko04915 Estrogen signaling pathway 8/201 131/7206 0.0297366899714 ko05110 Vibrio cholerae infection 5/201 63/7206 0.0305854742574 ko05210 Colorectal cancer 6/201 86/7206 0.0324992801976 ko04966 Collecting duct acid secretion 3/201 26/7206 0.0346875251084 ko04014 Ras signaling pathway 14/201 279/7206 0.037754357764 ko04360 Axon guidance 12/201 233/7206 0.0391887006428 ko05152 Tuberculosis 10/201 187/7206 0.0407384902175 ko04013 MAPK signaling pathway - fly 7/201 115/7206 0.0413490364188 ko04071 Sphingolipid signaling pathway 9/201 162/7206 0.0467384143957