ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	147/806	423/7206	1.00110718871e-40
ko05033	Nicotine addiction	43/806	56/7206	2.02426193116e-30
ko04724	Glutamatergic synapse	70/806	152/7206	5.4359303377e-28
ko05032	Morphine addiction	52/806	110/7206	1.10968601915e-21
ko04721	Synaptic vesicle cycle	42/806	80/7206	6.21677593604e-20
ko04727	GABAergic synapse	49/806	110/7206	4.09319563076e-19
ko04728	Dopaminergic synapse	66/806	185/7206	4.79944850458e-19
ko04723	Retrograde endocannabinoid signaling	61/806	175/7206	4.11184427829e-17
ko04713	Circadian entrainment	51/806	136/7206	5.37191088659e-16
ko04725	Cholinergic synapse	55/806	160/7206	3.10422201332e-15
ko04024	cAMP signaling pathway	77/806	279/7206	1.10753425101e-14
ko04911	Insulin secretion	40/806	117/7206	2.50902767234e-11
ko04726	Serotonergic synapse	44/806	137/7206	2.74770076731e-11
ko04742	Taste transduction	27/806	61/7206	5.13374205585e-11
ko04020	Calcium signaling pathway	62/806	265/7206	7.42919213589e-09
ko04744	Phototransduction	18/806	36/7206	8.01646610022e-09
ko04921	Oxytocin signaling pathway	52/806	209/7206	1.75335699893e-08
ko05031	Amphetamine addiction	30/806	91/7206	2.10036410534e-08
ko04261	Adrenergic signaling in cardiomyocytes	51/806	205/7206	2.52020884025e-08
ko05030	Cocaine addiction	25/806	73/7206	1.37312574804e-07
ko04720	Long-term potentiation	30/806	99/7206	1.77858564003e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	25/806	74/7206	1.85769297988e-07
ko04514	Cell adhesion molecules (CAMs)	35/806	130/7206	6.04988485131e-07
ko03040	Spliceosome	1/806	145/7206	8.49788489437e-07
ko04970	Salivary secretion	28/806	95/7206	8.59075945009e-07
ko04010	MAPK signaling pathway	64/806	321/7206	2.86505475645e-06
ko04060	Cytokine-cytokine receptor interaction	4/806	191/7206	3.61068210509e-06
ko05203	Viral carcinogenesis	10/806	277/7206	6.03818806959e-06
ko04730	Long-term depression	23/806	78/7206	8.07156012968e-06
ko04072	Phospholipase D signaling pathway	42/806	197/7206	2.83263497107e-05
ko05164	Influenza A	4/806	167/7206	3.25359630325e-05
ko04260	Cardiac muscle contraction	24/806	98/7206	0.000153464664065
ko04971	Gastric acid secretion	24/806	98/7206	0.000153464664065
ko04022	cGMP-PKG signaling pathway	43/806	216/7206	0.000158296054734
ko03013	RNA transport	5/806	166/7206	0.000160349869181
ko04120	Ubiquitin mediated proteolysis	3/806	138/7206	0.000168543017572
ko05168	Herpes simplex infection	6/806	182/7206	0.000180136169215
ko04972	Pancreatic secretion	26/806	111/7206	0.000197003154525
ko05322	Systemic lupus erythematosus	4/806	151/7206	0.000200277133046
ko04925	Aldosterone synthesis and secretion	25/806	105/7206	0.000223326873848
ko04966	Collecting duct acid secretion	10/806	26/7206	0.000287531271405
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	20/806	79/7206	0.000398888163339
ko04621	NOD-like receptor signaling pathway	5/806	157/7206	0.000453489141919
ko04070	Phosphatidylinositol signaling system	25/806	112/7206	0.000675619516237
ko05169	Epstein-Barr virus infection	9/806	206/7206	0.000699034483121
ko04360	Axon guidance	43/806	233/7206	0.000939657677407
ko04141	Protein processing in endoplasmic reticulum	8/806	184/7206	0.00130666170049
ko04612	Antigen processing and presentation	1/806	77/7206	0.0017394635588
ko04915	Estrogen signaling pathway	27/806	131/7206	0.00174949424132
ko03008	Ribosome biogenesis in eukaryotes	1/806	79/7206	0.00177742225922
ko05205	Proteoglycans in cancer	16/806	271/7206	0.00314315027138
ko04964	Proximal tubule bicarbonate reclamation	9/806	29/7206	0.00330656298507
ko04146	Peroxisome	2/806	89/7206	0.00346141840007
ko04740	Olfactory transduction	18/806	80/7206	0.00346989676799
ko05166	HTLV-I infection	18/806	292/7206	0.00425976645428
ko04110	Cell cycle	6/806	145/7206	0.00468278833344
ko04071	Sphingolipid signaling pathway	30/806	162/7206	0.00511769773626
ko04217	Necroptosis	9/806	178/7206	0.00550684173166
ko04745	Phototransduction - fly	10/806	38/7206	0.00737973650952
ko04064	NF-kappa B signaling pathway	3/806	96/7206	0.00816407114236
ko04640	Hematopoietic cell lineage	1/806	64/7206	0.00835118266596
ko04924	Renin secretion	18/806	86/7206	0.00851664415196
ko05161	Hepatitis B	9/806	173/7206	0.00976042212527
ko04976	Bile secretion	17/806	80/7206	0.0108768116036
ko04014	Ras signaling pathway	45/806	279/7206	0.0113628814376
ko05162	Measles	5/806	120/7206	0.0120104939469
ko05110	Vibrio cholerae infection	14/806	63/7206	0.0134941771295
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/806	14/7206	0.0145999227539
ko05140	Leishmaniasis	2/806	75/7206	0.0149745874423
ko05414	Dilated cardiomyopathy	21/806	112/7206	0.0150807470535
ko04140	Autophagy - animal	9/806	164/7206	0.0166873980325
ko04350	TGF-beta signaling pathway	4/806	103/7206	0.0167228924744
ko00480	Glutathione metabolism	1/806	55/7206	0.0178984427046
ko05231	Choline metabolism in cancer	24/806	134/7206	0.0179405894758
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/806	59/7206	0.0194196301264
ko04510	Focal adhesion	16/806	240/7206	0.0216578210164
ko00240	Pyrimidine metabolism	5/806	110/7206	0.021668392085
ko04540	Gap junction	23/806	128/7206	0.0222252594012
ko03018	RNA degradation	3/806	84/7206	0.0222871004097
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/806	182/7206	0.0232276911921
ko05200	Pathways in cancer	40/806	492/7206	0.0259759493187
ko00280	Valine, leucine and isoleucine degradation	1/806	54/7206	0.0270212557763
ko05016	Huntington's disease	14/806	215/7206	0.0273392805936
ko05206	MicroRNAs in cancer	11/806	177/7206	0.0298030216288
ko01200	Carbon metabolism	7/806	128/7206	0.0339327656874
ko05410	Hypertrophic cardiomyopathy (HCM)	18/806	100/7206	0.0368659169239
ko05219	Bladder cancer	1/806	48/7206	0.038316436578
ko04750	Inflammatory mediator regulation of TRP channels	21/806	122/7206	0.0414072481216
ko04666	Fc gamma R-mediated phagocytosis	21/806	122/7206	0.0414072481216
ko04330	Notch signaling pathway	2/806	62/7206	0.0422429080036
ko05120	Epithelial cell signaling in Helicobacter pylori infection	17/806	92/7206	0.0431936524374
ko05145	Toxoplasmosis	7/806	126/7206	0.0447315876865
ko04973	Carbohydrate digestion and absorption	9/806	42/7206	0.0461940113883
ko04930	Type II diabetes mellitus	11/806	54/7206	0.0468014751727
ko05215	Prostate cancer	6/806	111/7206	0.0486821011571