ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	126/653	423/7206	7.68611318301e-37
ko05033	Nicotine addiction	40/653	56/7206	6.60657655094e-30
ko04724	Glutamatergic synapse	59/653	152/7206	7.1828309479e-24
ko04727	GABAergic synapse	42/653	110/7206	5.65910742272e-17
ko05032	Morphine addiction	42/653	110/7206	5.65910742272e-17
ko04728	Dopaminergic synapse	54/653	185/7206	1.60423363052e-15
ko04723	Retrograde endocannabinoid signaling	50/653	175/7206	4.80501386649e-14
ko04721	Synaptic vesicle cycle	32/653	80/7206	6.86606863633e-14
ko04713	Circadian entrainment	42/653	136/7206	3.05321238981e-13
ko04024	cAMP signaling pathway	63/653	279/7206	4.97717904597e-12
ko04742	Taste transduction	25/653	61/7206	2.07916757167e-11
ko04725	Cholinergic synapse	42/653	160/7206	1.1133568843e-10
ko04911	Insulin secretion	33/653	117/7206	1.58603653772e-09
ko05030	Cocaine addiction	25/653	73/7206	1.91444882251e-09
ko05014	Amyotrophic lateral sclerosis (ALS)	25/653	74/7206	2.64841320006e-09
ko04261	Adrenergic signaling in cardiomyocytes	46/653	205/7206	6.49613809411e-09
ko04921	Oxytocin signaling pathway	45/653	209/7206	2.41107899783e-08
ko05031	Amphetamine addiction	26/653	91/7206	6.58782734835e-08
ko04360	Axon guidance	46/653	233/7206	2.96391650074e-07
ko04514	Cell adhesion molecules (CAMs)	31/653	130/7206	3.44413522538e-07
ko04726	Serotonergic synapse	31/653	137/7206	1.17550263139e-06
ko04720	Long-term potentiation	25/653	99/7206	1.53666042226e-06
ko04010	MAPK signaling pathway	55/653	321/7206	3.30233313024e-06
ko04020	Calcium signaling pathway	47/653	265/7206	5.48485488612e-06
ko03040	Spliceosome	1/653	145/7206	2.61998412675e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/653	79/7206	5.73195259672e-05
ko05203	Viral carcinogenesis	8/653	277/7206	6.29540879056e-05
ko04970	Salivary secretion	21/653	95/7206	8.94855518115e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/653	14/7206	9.45635769227e-05
ko04730	Long-term depression	18/653	78/7206	0.000158004894951
ko04260	Cardiac muscle contraction	21/653	98/7206	0.000228182066164
ko04972	Pancreatic secretion	22/653	111/7206	0.000353200169614
ko04621	NOD-like receptor signaling pathway	3/653	157/7206	0.000375493802792
ko04120	Ubiquitin mediated proteolysis	2/653	138/7206	0.000430837527378
ko04060	Cytokine-cytokine receptor interaction	5/653	191/7206	0.000503757525733
ko05205	Proteoglycans in cancer	10/653	271/7206	0.000755489265654
ko05322	Systemic lupus erythematosus	3/653	151/7206	0.000790664332182
ko03013	RNA transport	4/653	166/7206	0.000892696558036
ko05164	Influenza A	4/653	167/7206	0.000900131691959
ko04915	Estrogen signaling pathway	24/653	131/7206	0.00096510324015
ko05168	Herpes simplex infection	5/653	182/7206	0.000979004760074
ko05414	Dilated cardiomyopathy	21/653	112/7206	0.00123074515699
ko04022	cGMP-PKG signaling pathway	34/653	216/7206	0.00153559455809
ko04930	Type II diabetes mellitus	12/653	54/7206	0.00270997520627
ko00240	Pyrimidine metabolism	2/653	110/7206	0.00381737474582
ko04146	Peroxisome	1/653	89/7206	0.00432667116412
ko01200	Carbon metabolism	3/653	128/7206	0.00450331613144
ko04072	Phospholipase D signaling pathway	30/653	197/7206	0.00511852008702
ko00515	Mannose type O-glycan biosynthesis	7/653	25/7206	0.00547062363652
ko03018	RNA degradation	1/653	84/7206	0.00625771726259
ko04971	Gastric acid secretion	17/653	98/7206	0.00739866721544
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/653	15/7206	0.00836950543384
ko04141	Protein processing in endoplasmic reticulum	7/653	184/7206	0.00877918615594
ko04612	Antigen processing and presentation	1/653	77/7206	0.0089659359046
ko03008	Ribosome biogenesis in eukaryotes	1/653	79/7206	0.00906962531217
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/653	59/7206	0.0094180865997
ko04015	Rap1 signaling pathway	38/653	278/7206	0.0100789688514
ko04217	Necroptosis	7/653	178/7206	0.0116760169231
ko05410	Hypertrophic cardiomyopathy (HCM)	17/653	100/7206	0.0122579373638
ko00310	Lysine degradation	1/653	73/7206	0.0130958547085
ko05169	Epstein-Barr virus infection	9/653	206/7206	0.0135041953958
ko04214	Apoptosis - fly	1/653	72/7206	0.0202127770127
ko05162	Measles	4/653	120/7206	0.0237204257715
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/653	182/7206	0.0252323582906
ko04071	Sphingolipid signaling pathway	23/653	162/7206	0.0264512075926
ko04640	Hematopoietic cell lineage	1/653	64/7206	0.0278292802055
ko04540	Gap junction	19/653	128/7206	0.0285915379783
ko05146	Amoebiasis	3/653	99/7206	0.0328204762577
ko04925	Aldosterone synthesis and secretion	16/653	105/7206	0.037544390613
ko02024	Quorum sensing	4/653	15/7206	0.0406471001616
ko00512	Mucin type O-glycan biosynthesis	6/653	29/7206	0.042366779453
ko04964	Proximal tubule bicarbonate reclamation	6/653	29/7206	0.042366779453
ko00561	Glycerolipid metabolism	1/653	63/7206	0.0426091672234
ko04014	Ras signaling pathway	35/653	279/7206	0.0431434317426
ko04064	NF-kappa B signaling pathway	3/653	96/7206	0.0461414217778