ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	166/1061	423/7206	1.22095783474e-37
ko04724	Glutamatergic synapse	77/1061	152/7206	4.53038901389e-26
ko05033	Nicotine addiction	43/1061	56/7206	2.17127236198e-25
ko05032	Morphine addiction	57/1061	110/7206	3.49937462629e-20
ko04728	Dopaminergic synapse	76/1061	185/7206	8.79234768326e-19
ko04713	Circadian entrainment	61/1061	136/7206	1.64608092633e-17
ko04721	Synaptic vesicle cycle	44/1061	80/7206	3.78263190369e-17
ko04727	GABAergic synapse	53/1061	110/7206	4.82703009687e-17
ko04725	Cholinergic synapse	63/1061	160/7206	1.04318977796e-14
ko04024	cAMP signaling pathway	91/1061	279/7206	1.70358098643e-14
ko04020	Calcium signaling pathway	85/1061	265/7206	3.10899063709e-13
ko04723	Retrograde endocannabinoid signaling	64/1061	175/7206	3.695369059e-13
ko04726	Serotonergic synapse	53/1061	137/7206	3.27932784257e-12
ko04911	Insulin secretion	47/1061	117/7206	1.18308319172e-11
ko04742	Taste transduction	31/1061	61/7206	2.89481598046e-11
ko05031	Amphetamine addiction	38/1061	91/7206	2.95141455427e-10
ko04921	Oxytocin signaling pathway	66/1061	209/7206	4.73315537764e-10
ko04744	Phototransduction	21/1061	36/7206	1.71097768183e-09
ko04720	Long-term potentiation	37/1061	99/7206	1.91525477286e-08
ko03040	Spliceosome	2/1061	145/7206	4.1005175568e-08
ko03010	Ribosome	1/1061	129/7206	4.57145638971e-08
ko04261	Adrenergic signaling in cardiomyocytes	59/1061	205/7206	1.91020998588e-07
ko04070	Phosphatidylinositol signaling system	38/1061	112/7206	2.55790332617e-07
ko05030	Cocaine addiction	27/1061	73/7206	2.02529760409e-06
ko04360	Axon guidance	61/1061	233/7206	3.20001872633e-06
ko03013	RNA transport	6/1061	166/7206	3.93417900328e-06
ko04925	Aldosterone synthesis and secretion	34/1061	105/7206	4.36267745427e-06
ko05322	Systemic lupus erythematosus	5/1061	151/7206	6.83841287119e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	26/1061	74/7206	9.31924483381e-06
ko05168	Herpes simplex infection	8/1061	182/7206	1.04472768443e-05
ko04970	Salivary secretion	31/1061	95/7206	1.1964935344e-05
ko04014	Ras signaling pathway	68/1061	279/7206	1.38472298147e-05
ko04514	Cell adhesion molecules (CAMs)	38/1061	130/7206	1.60759617683e-05
ko04010	MAPK signaling pathway	76/1061	321/7206	1.64275461756e-05
ko04971	Gastric acid secretion	31/1061	98/7206	1.83686135052e-05
ko05203	Viral carcinogenesis	18/1061	277/7206	2.78175914744e-05
ko04120	Ubiquitin mediated proteolysis	5/1061	138/7206	2.92845035122e-05
ko04745	Phototransduction - fly	16/1061	38/7206	3.94112109904e-05
ko04621	NOD-like receptor signaling pathway	7/1061	157/7206	5.35189978377e-05
ko05164	Influenza A	8/1061	167/7206	5.72428828684e-05
ko04141	Protein processing in endoplasmic reticulum	10/1061	184/7206	8.47983908759e-05
ko04612	Antigen processing and presentation	1/1061	77/7206	0.000126966252593
ko04966	Collecting duct acid secretion	12/1061	26/7206	0.000127178001902
ko04740	Olfactory transduction	25/1061	80/7206	0.000168144460371
ko04710	Circadian rhythm	16/1061	43/7206	0.000227547464022
ko04730	Long-term depression	24/1061	78/7206	0.000280333640905
ko04072	Phospholipase D signaling pathway	48/1061	197/7206	0.000312441504014
ko04972	Pancreatic secretion	31/1061	111/7206	0.000345006473607
ko04964	Proximal tubule bicarbonate reclamation	12/1061	29/7206	0.000445835023247
ko03008	Ribosome biogenesis in eukaryotes	2/1061	79/7206	0.000626589297163
ko04750	Inflammatory mediator regulation of TRP channels	32/1061	122/7206	0.000726319933359
ko04022	cGMP-PKG signaling pathway	50/1061	216/7206	0.000839639016775
ko04060	Cytokine-cytokine receptor interaction	13/1061	191/7206	0.000877166640905
ko05140	Leishmaniasis	2/1061	75/7206	0.000919012947023
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/1061	79/7206	0.00107430848825
ko00562	Inositol phosphate metabolism	25/1061	89/7206	0.00125475553384
ko04064	NF-kappa B signaling pathway	4/1061	96/7206	0.00130892346418
ko04110	Cell cycle	9/1061	145/7206	0.00194437379376
ko04626	Plant-pathogen interaction	8/1061	18/7206	0.00237627896667
ko05166	HTLV-I infection	26/1061	292/7206	0.00308631379012
ko04540	Gap junction	31/1061	128/7206	0.0036646381749
ko05110	Vibrio cholerae infection	18/1061	63/7206	0.00383651519631
ko04015	Rap1 signaling pathway	58/1061	278/7206	0.00435002725617
ko05161	Hepatitis B	13/1061	173/7206	0.00463309334246
ko04260	Cardiac muscle contraction	25/1061	98/7206	0.00569084272359
ko04915	Estrogen signaling pathway	31/1061	131/7206	0.00584608055305
ko05169	Epstein-Barr virus infection	17/1061	206/7206	0.00677156412228
ko04924	Renin secretion	22/1061	86/7206	0.00831154761614
ko05162	Measles	8/1061	120/7206	0.00904070684173
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1061	14/7206	0.0104576433125
ko03420	Nucleotide excision repair	1/1061	46/7206	0.0107316907992
ko04930	Type II diabetes mellitus	15/1061	54/7206	0.0111906411232
ko04960	Aldosterone-regulated sodium reabsorption	12/1061	41/7206	0.0139337941131
ko05205	Proteoglycans in cancer	26/1061	271/7206	0.0141561175687
ko05145	Toxoplasmosis	9/1061	126/7206	0.0151294833898
ko05214	Glioma	20/1061	79/7206	0.015164931614
ko03022	Basal transcription factors	1/1061	44/7206	0.0163950166933
ko04630	Jak-STAT signaling pathway	10/1061	132/7206	0.0178663545272
ko00280	Valine, leucine and isoleucine degradation	2/1061	54/7206	0.0188959538131
ko00480	Glutathione metabolism	2/1061	55/7206	0.0195580045827
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1061	40/7206	0.0235170098404
ko05016	Huntington's disease	20/1061	215/7206	0.0240466131574
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/1061	59/7206	0.0262441726671
ko00590	Arachidonic acid metabolism	2/1061	52/7206	0.0279414443627
ko04214	Apoptosis - fly	4/1061	72/7206	0.0280159646591
ko04330	Notch signaling pathway	3/1061	62/7206	0.0285746971798
ko04622	RIG-I-like receptor signaling pathway	3/1061	62/7206	0.0285746971798
ko05414	Dilated cardiomyopathy	25/1061	112/7206	0.030396102425
ko04217	Necroptosis	16/1061	178/7206	0.0314079379952
ko04711	Circadian rhythm - fly	5/1061	13/7206	0.0316400933436
ko04146	Peroxisome	6/1061	89/7206	0.0337296949828
ko04610	Complement and coagulation cascades	5/1061	79/7206	0.0363013090217
ko05230	Central carbon metabolism in cancer	19/1061	81/7206	0.0383413946194
ko05219	Bladder cancer	2/1061	48/7206	0.0387671820209
ko04371	Apelin signaling pathway	36/1061	177/7206	0.0405614604145
ko04722	Neurotrophin signaling pathway	33/1061	160/7206	0.0414367477108
ko04922	Glucagon signaling pathway	27/1061	128/7206	0.0442210024536
ko04657	IL-17 signaling pathway	6/1061	87/7206	0.0458631513637
ko05133	Pertussis	6/1061	87/7206	0.0458631513637
ko05410	Hypertrophic cardiomyopathy (HCM)	22/1061	100/7206	0.0459289569426
ko04973	Carbohydrate digestion and absorption	11/1061	42/7206	0.0468098069154
ko05231	Choline metabolism in cancer	28/1061	134/7206	0.0484311575032