ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	68/799	152/7206	1.64308915788e-26
ko04080	Neuroactive ligand-receptor interaction	124/799	423/7206	1.72741685112e-26
ko05033	Nicotine addiction	38/799	56/7206	6.78520480219e-24
ko05032	Morphine addiction	53/799	110/7206	9.46302562352e-23
ko04727	GABAergic synapse	52/799	110/7206	7.39031763584e-22
ko04713	Circadian entrainment	53/799	136/7206	1.32610696716e-17
ko04723	Retrograde endocannabinoid signaling	60/799	175/7206	1.21678118365e-16
ko04725	Cholinergic synapse	55/799	160/7206	2.11463457636e-15
ko04024	cAMP signaling pathway	77/799	279/7206	8.39927489045e-15
ko04728	Dopaminergic synapse	59/799	185/7206	9.53462656327e-15
ko04721	Synaptic vesicle cycle	33/799	80/7206	3.08754066738e-12
ko04911	Insulin secretion	40/799	117/7206	1.90401216392e-11
ko04020	Calcium signaling pathway	65/799	265/7206	3.5545532565e-10
ko04726	Serotonergic synapse	41/799	137/7206	1.13947521014e-09
ko04744	Phototransduction	18/799	36/7206	6.96725564215e-09
ko04921	Oxytocin signaling pathway	51/799	209/7206	3.24110431103e-08
ko04742	Taste transduction	23/799	61/7206	4.80976418825e-08
ko04261	Adrenergic signaling in cardiomyocytes	48/799	205/7206	3.48030280181e-07
ko05031	Amphetamine addiction	27/799	91/7206	9.80329753182e-07
ko04010	MAPK signaling pathway	65/799	321/7206	1.00575315428e-06
ko04360	Axon guidance	51/799	233/7206	1.22395511674e-06
ko03040	Spliceosome	1/799	145/7206	1.34182921332e-06
ko04072	Phospholipase D signaling pathway	45/799	197/7206	1.51415698768e-06
ko04022	cGMP-PKG signaling pathway	48/799	216/7206	1.54839665439e-06
ko04720	Long-term potentiation	27/799	99/7206	5.86449380228e-06
ko05030	Cocaine addiction	22/799	73/7206	7.44892606591e-06
ko04970	Salivary secretion	26/799	95/7206	8.12400261774e-06
ko04070	Phosphatidylinositol signaling system	28/799	112/7206	2.54187453163e-05
ko04514	Cell adhesion molecules (CAMs)	31/799	130/7206	2.77396345111e-05
ko05322	Systemic lupus erythematosus	3/799	151/7206	3.63258898422e-05
ko03013	RNA transport	4/799	166/7206	4.7139283267e-05
ko04730	Long-term depression	21/799	78/7206	7.74856593267e-05
ko04014	Ras signaling pathway	53/799	279/7206	8.35429168116e-05
ko04972	Pancreatic secretion	26/799	111/7206	0.000177412358721
ko05203	Viral carcinogenesis	13/799	277/7206	0.000190505731932
ko05014	Amyotrophic lateral sclerosis (ALS)	19/799	74/7206	0.000488198705719
ko04141	Protein processing in endoplasmic reticulum	7/799	184/7206	0.00050779741407
ko04930	Type II diabetes mellitus	15/799	54/7206	0.000558757360504
ko00240	Pyrimidine metabolism	2/799	110/7206	0.000568948220485
ko04964	Proximal tubule bicarbonate reclamation	10/799	29/7206	0.000739968955355
ko04925	Aldosterone synthesis and secretion	23/799	105/7206	0.00136527884772
ko04915	Estrogen signaling pathway	27/799	131/7206	0.00168250122932
ko04610	Complement and coagulation cascades	1/799	79/7206	0.00176007778536
ko05168	Herpes simplex infection	8/799	182/7206	0.00177775344776
ko04621	NOD-like receptor signaling pathway	6/799	157/7206	0.00180408951112
ko05164	Influenza A	7/799	167/7206	0.00248623539566
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/799	14/7206	0.0024979620809
ko04612	Antigen processing and presentation	1/799	77/7206	0.0027308842118
ko04260	Cardiac muscle contraction	21/799	98/7206	0.00291845253769
ko04976	Bile secretion	18/799	80/7206	0.00329008865857
ko04960	Aldosterone-regulated sodium reabsorption	11/799	41/7206	0.00402002017696
ko04973	Carbohydrate digestion and absorption	11/799	42/7206	0.00491371769359
ko04971	Gastric acid secretion	20/799	98/7206	0.00560658036914
ko04710	Circadian rhythm	11/799	43/7206	0.00595767465457
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/799	79/7206	0.00610215670866
ko04060	Cytokine-cytokine receptor interaction	10/799	191/7206	0.0068585816379
ko00562	Inositol phosphate metabolism	18/799	89/7206	0.00996647697237
ko04110	Cell cycle	7/799	145/7206	0.0109600186551
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/799	59/7206	0.0120329199931
ko00330	Arginine and proline metabolism	1/799	61/7206	0.0123550720439
ko05414	Dilated cardiomyopathy	21/799	112/7206	0.0143473133048
ko04924	Renin secretion	17/799	86/7206	0.0149181847623
ko04918	Thyroid hormone synthesis	17/799	86/7206	0.0149181847623
ko04371	Apelin signaling pathway	30/799	177/7206	0.015263263496
ko04217	Necroptosis	10/799	178/7206	0.0153142645084
ko04923	Regulation of lipolysis in adipocytes	16/799	77/7206	0.015618688149
ko04146	Peroxisome	3/799	89/7206	0.0160884027517
ko05231	Choline metabolism in cancer	24/799	134/7206	0.0172060428679
ko05205	Proteoglycans in cancer	18/799	271/7206	0.0174241227948
ko04740	Olfactory transduction	16/799	80/7206	0.0180838927019
ko04120	Ubiquitin mediated proteolysis	7/799	138/7206	0.0194619346193
ko04966	Collecting duct acid secretion	7/799	26/7206	0.0199797794292
ko04540	Gap junction	23/799	128/7206	0.0216501339194
ko05169	Epstein-Barr virus infection	13/799	206/7206	0.0240672864989
ko05110	Vibrio cholerae infection	13/799	63/7206	0.0242282732647
ko04015	Rap1 signaling pathway	43/799	278/7206	0.024434034902
ko00590	Arachidonic acid metabolism	1/799	52/7206	0.0262789228337
ko05016	Huntington's disease	14/799	215/7206	0.0272570407528
ko04064	NF-kappa B signaling pathway	4/799	96/7206	0.0313688931493
ko05131	Shigellosis	3/799	82/7206	0.0315896964726
ko04213	Longevity regulating pathway - multiple species	16/799	86/7206	0.03601586275
ko05210	Colorectal cancer	16/799	86/7206	0.03601586275
ko04750	Inflammatory mediator regulation of TRP channels	21/799	122/7206	0.0401416765986
ko04722	Neurotrophin signaling pathway	26/799	160/7206	0.0412215102008
ko04919	Thyroid hormone signaling pathway	24/799	143/7206	0.0419845261799
ko04640	Hematopoietic cell lineage	2/799	64/7206	0.0429027231655
ko05130	Pathogenic Escherichia coli infection	3/799	77/7206	0.0431023844766
ko05230	Central carbon metabolism in cancer	15/799	81/7206	0.0472733638335
ko04711	Circadian rhythm - fly	4/799	13/7206	0.0473885503368