ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	156/928	423/7206	6.16068791499e-39
ko04724	Glutamatergic synapse	74/928	152/7206	1.81630756638e-27
ko05033	Nicotine addiction	42/928	56/7206	1.72768413514e-26
ko04728	Dopaminergic synapse	75/928	185/7206	1.12615137553e-21
ko05032	Morphine addiction	55/928	110/7206	2.27831791517e-21
ko04721	Synaptic vesicle cycle	44/928	80/7206	1.93767629381e-19
ko04713	Circadian entrainment	59/928	136/7206	5.64243100335e-19
ko04727	GABAergic synapse	50/928	110/7206	2.70895042036e-17
ko04024	cAMP signaling pathway	87/928	279/7206	2.58794209959e-16
ko04723	Retrograde endocannabinoid signaling	63/928	175/7206	2.24766089778e-15
ko04725	Cholinergic synapse	59/928	160/7206	5.13513948336e-15
ko04726	Serotonergic synapse	51/928	137/7206	2.49164289638e-13
ko04020	Calcium signaling pathway	78/928	265/7206	3.65952157628e-13
ko05031	Amphetamine addiction	38/928	91/7206	4.94487988067e-12
ko04921	Oxytocin signaling pathway	63/928	209/7206	2.78107441046e-11
ko04911	Insulin secretion	43/928	117/7206	3.18579273276e-11
ko04720	Long-term potentiation	38/928	99/7206	1.02319708872e-10
ko04742	Taste transduction	28/928	61/7206	2.26395098396e-10
ko04744	Phototransduction	20/928	36/7206	1.23943555119e-09
ko04261	Adrenergic signaling in cardiomyocytes	57/928	205/7206	7.69888745396e-09
ko05030	Cocaine addiction	27/928	73/7206	1.32271532902e-07
ko03010	Ribosome	1/928	129/7206	7.5177713761e-07
ko03040	Spliceosome	2/928	145/7206	9.43873050499e-07
ko04925	Aldosterone synthesis and secretion	32/928	105/7206	1.9914952905e-06
ko05322	Systemic lupus erythematosus	3/928	151/7206	3.22337919197e-06
ko04966	Collecting duct acid secretion	13/928	26/7206	5.08435374593e-06
ko05203	Viral carcinogenesis	13/928	277/7206	5.78109630348e-06
ko04970	Salivary secretion	29/928	95/7206	6.41480511834e-06
ko04745	Phototransduction - fly	16/928	38/7206	7.01727379014e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	24/928	74/7206	9.54353676508e-06
ko04010	MAPK signaling pathway	69/928	321/7206	1.13295574487e-05
ko04060	Cytokine-cytokine receptor interaction	7/928	191/7206	2.33814513981e-05
ko04971	Gastric acid secretion	28/928	98/7206	2.75050861722e-05
ko05168	Herpes simplex infection	7/928	182/7206	4.42610075597e-05
ko04514	Cell adhesion molecules (CAMs)	34/928	130/7206	4.9366091729e-05
ko05164	Influenza A	6/928	167/7206	5.64144520688e-05
ko04120	Ubiquitin mediated proteolysis	4/928	138/7206	8.68457928809e-05
ko04730	Long-term depression	23/928	78/7206	9.9712430108e-05
ko04070	Phosphatidylinositol signaling system	29/928	112/7206	0.000163064294169
ko04022	cGMP-PKG signaling pathway	47/928	216/7206	0.00026203275003
ko05110	Vibrio cholerae infection	19/928	63/7206	0.000399060319492
ko04922	Glucagon signaling pathway	31/928	128/7206	0.000425458157197
ko04141	Protein processing in endoplasmic reticulum	9/928	184/7206	0.000474234299341
ko05162	Measles	4/928	120/7206	0.000507102055801
ko04740	Olfactory transduction	22/928	80/7206	0.000540485703519
ko04110	Cell cycle	6/928	145/7206	0.000614060097324
ko04621	NOD-like receptor signaling pathway	7/928	157/7206	0.000639391210635
ko04072	Phospholipase D signaling pathway	42/928	197/7206	0.000756830121504
ko03013	RNA transport	8/928	166/7206	0.000896618884693
ko04626	Plant-pathogen interaction	8/928	18/7206	0.000974111179526
ko05169	Epstein-Barr virus infection	12/928	206/7206	0.00140206431583
ko04064	NF-kappa B signaling pathway	3/928	96/7206	0.001838594284
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	20/928	79/7206	0.00214870618163
ko04510	Focal adhesion	16/928	240/7206	0.00226751848856
ko05166	HTLV-I infection	21/928	292/7206	0.00229825466659
ko04972	Pancreatic secretion	26/928	111/7206	0.00230048519118
ko04964	Proximal tubule bicarbonate reclamation	10/928	29/7206	0.00237291171143
ko04612	Antigen processing and presentation	2/928	77/7206	0.00317450348562
ko03008	Ribosome biogenesis in eukaryotes	2/928	79/7206	0.00335329657127
ko04260	Cardiac muscle contraction	23/928	98/7206	0.00347170745921
ko04330	Notch signaling pathway	1/928	62/7206	0.00354357150732
ko05161	Hepatitis B	10/928	173/7206	0.00374593930757
ko05200	Pathways in cancer	43/928	492/7206	0.00414163516985
ko05140	Leishmaniasis	2/928	75/7206	0.00471708747994
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/928	14/7206	0.00537585926705
ko04915	Estrogen signaling pathway	28/928	131/7206	0.00548731400742
ko04014	Ras signaling pathway	52/928	279/7206	0.00598278249752
ko00480	Glutathione metabolism	1/928	55/7206	0.00772447769502
ko04924	Renin secretion	20/928	86/7206	0.0084093467547
ko04750	Inflammatory mediator regulation of TRP channels	26/928	122/7206	0.00887701621842
ko04710	Circadian rhythm	12/928	43/7206	0.00915353061759
ko05205	Proteoglycans in cancer	21/928	271/7206	0.00933406648165
ko04360	Axon guidance	44/928	233/7206	0.00933547497282
ko05217	Basal cell carcinoma	2/928	68/7206	0.00970907714106
ko00562	Inositol phosphate metabolism	20/928	89/7206	0.010319637976
ko04610	Complement and coagulation cascades	3/928	79/7206	0.0106252486993
ko00590	Arachidonic acid metabolism	1/928	52/7206	0.0114486159436
ko00010	Glycolysis / Gluconeogenesis	17/928	74/7206	0.0139371238029
ko00240	Pyrimidine metabolism	6/928	110/7206	0.0145484236647
ko05215	Prostate cancer	6/928	111/7206	0.0145675810428
ko04657	IL-17 signaling pathway	4/928	87/7206	0.0152983081852
ko04540	Gap junction	26/928	128/7206	0.015944686442
ko04630	Jak-STAT signaling pathway	8/928	132/7206	0.0173486211165
ko05120	Epithelial cell signaling in Helicobacter pylori infection	20/928	92/7206	0.0174229442972
ko04214	Apoptosis - fly	3/928	72/7206	0.0210223811656
ko04115	p53 signaling pathway	3/928	74/7206	0.0215176871298
ko04930	Type II diabetes mellitus	13/928	54/7206	0.0224114701982
ko04210	Apoptosis	13/928	180/7206	0.0233829299769
ko00071	Fatty acid degradation	1/928	45/7206	0.0248717774486
ko03420	Nucleotide excision repair	1/928	46/7206	0.0250668455942
ko00512	Mucin type O-glycan biosynthesis	8/928	29/7206	0.0263102744192
ko05202	Transcriptional misregulation in cancer	14/928	188/7206	0.0265112886143
ko04550	Signaling pathways regulating pluripotency of stem cells	12/928	165/7206	0.0332709028425
ko00680	Methane metabolism	9/928	34/7206	0.0337688161487
ko04146	Peroxisome	5/928	89/7206	0.0377385153172
ko05222	Small cell lung cancer	5/928	89/7206	0.0377385153172
ko03022	Basal transcription factors	1/928	44/7206	0.038086868249
ko04668	TNF signaling pathway	8/928	120/7206	0.0388517487126
ko00280	Valine, leucine and isoleucine degradation	2/928	54/7206	0.04044011881
ko05321	Inflammatory bowel disease (IBD)	2/928	56/7206	0.0418514484466
ko05230	Central carbon metabolism in cancer	17/928	81/7206	0.0428144510191
ko05414	Dilated cardiomyopathy	22/928	112/7206	0.0447518566777
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/928	59/7206	0.0480511651376
ko05034	Alcoholism	41/928	238/7206	0.0485162183706
ko05016	Huntington's disease	18/928	215/7206	0.0488345953208