ko pathway ratio_in_study ratio_in_pop p_value ko04668 TNF signaling pathway 19/127 120/7206 1.59675474948e-13 ko04380 Osteoclast differentiation 16/127 134/7206 1.17918099145e-09 ko04064 NF-kappa B signaling pathway 13/127 96/7206 9.96950165116e-09 ko04621 NOD-like receptor signaling pathway 15/127 157/7206 8.6121256419e-08 ko05164 Influenza A 14/127 167/7206 1.19292834145e-06 ko04620 Toll-like receptor signaling pathway 11/127 100/7206 1.23678454987e-06 ko05166 HTLV-I infection 18/127 292/7206 3.06353642999e-06 ko05140 Leishmaniasis 9/127 75/7206 5.81496358531e-06 ko04060 Cytokine-cytokine receptor interaction 14/127 191/7206 5.8759889248e-06 ko05167 Kaposi's sarcoma-associated herpesvirus infection 14/127 191/7206 5.8759889248e-06 ko04210 Apoptosis 13/127 180/7206 1.51550452622e-05 ko05168 Herpes simplex infection 13/127 182/7206 1.70667910086e-05 ko05161 Hepatitis B 12/127 173/7206 4.89108814164e-05 ko05145 Toxoplasmosis 10/127 126/7206 6.9343602347e-05 ko05160 Hepatitis C 11/127 153/7206 7.39240245663e-05 ko04657 IL-17 signaling pathway 8/127 87/7206 0.000135870864229 ko05323 Rheumatoid arthritis 8/127 89/7206 0.000159460156939 ko05418 Fluid shear stress and atherosclerosis 11/127 173/7206 0.00022141337491 ko00120 Primary bile acid biosynthesis 4/127 20/7206 0.00035820426887 ko04630 Jak-STAT signaling pathway 9/127 132/7206 0.000505284850767 ko04622 RIG-I-like receptor signaling pathway 6/127 62/7206 0.000729960107136 ko05133 Pertussis 7/127 87/7206 0.000812496124143 ko05144 Malaria 5/127 45/7206 0.00109147941132 ko05120 Epithelial cell signaling in Helicobacter pylori infection 7/127 92/7206 0.00113282864385 ko05162 Measles 8/127 120/7206 0.00120374210091 ko04660 T cell receptor signaling pathway 8/127 124/7206 0.00148740909802 ko04624 Toll and Imd signaling pathway 5/127 49/7206 0.00161058450465 ko05142 Chagas disease (American trypanosomiasis) 8/127 130/7206 0.00200996856945 ko05143 African trypanosomiasis 4/127 32/7206 0.00225793592953 ko04933 AGE-RAGE signaling pathway in diabetic complications 8/127 135/7206 0.00254780432261 ko04137 Mitophagy - animal 6/127 82/7206 0.00312359762604 ko05169 Epstein-Barr virus infection 10/127 206/7206 0.00333915899087 ko04672 Intestinal immune network for IgA production 4/127 37/7206 0.00387527587576 ko04217 Necroptosis 9/127 178/7206 0.00406998379323 ko04623 Cytosolic DNA-sensing pathway 4/127 41/7206 0.00562933735087 ko04080 Neuroactive ligand-receptor interaction 1/127 423/7206 0.00685692398297 ko05330 Allograft rejection 3/127 24/7206 0.00825664446052 ko04062 Chemokine signaling pathway 9/127 201/7206 0.00887836075526 ko05134 Legionellosis 5/127 74/7206 0.00959904545774 ko04612 Antigen processing and presentation 5/127 77/7206 0.0112934206292 ko05131 Shigellosis 5/127 82/7206 0.0145523691076 ko04932 Non-alcoholic fatty liver disease (NAFLD) 8/127 182/7206 0.014822506599 ko05340 Primary immunodeficiency 3/127 30/7206 0.0153423950606 ko04142 Lysosome 7/127 151/7206 0.0170278767997 ko04670 Leukocyte transendothelial migration 7/127 151/7206 0.0170278767997 ko05152 Tuberculosis 8/127 187/7206 0.017196901066 ko04940 Type I diabetes mellitus 3/127 32/7206 0.0182730671372 ko04662 B cell receptor signaling pathway 5/127 88/7206 0.0192312280799 ko04920 Adipocytokine signaling pathway 5/127 89/7206 0.0200966808111 ko04722 Neurotrophin signaling pathway 7/127 160/7206 0.0226317677565 ko04145 Phagosome 7/127 162/7206 0.0240322146266 ko05150 Staphylococcus aureus infection 3/127 36/7206 0.0250040892657 ko04915 Estrogen signaling pathway 6/127 131/7206 0.0278551452999 ko04010 MAPK signaling pathway 11/127 321/7206 0.0286559886235 ko04931 Insulin resistance 6/127 137/7206 0.0336719956011 ko00660 C5-Branched dibasic acid metabolism 1/127 2/7206 0.034940194606 ko05310 Asthma 2/127 17/7206 0.0352633813512 ko05332 Graft-versus-host disease 2/127 18/7206 0.0392219515367 ko04115 p53 signaling pathway 4/127 74/7206 0.0411340980612 ko04215 Apoptosis - multiple species 3/127 47/7206 0.0494411230574