ko pathway ratio_in_study ratio_in_pop p_value ko04668 TNF signaling pathway 4/11 120/7206 2.20556234989e-05 ko01521 EGFR tyrosine kinase inhibitor resistance 3/11 106/7206 0.000468521015103 ko04012 ErbB signaling pathway 3/11 109/7206 0.000508560580687 ko05205 Proteoglycans in cancer 4/11 271/7206 0.00052374312698 ko05215 Prostate cancer 3/11 111/7206 0.000536442019282 ko04915 Estrogen signaling pathway 3/11 131/7206 0.000870763769242 ko04931 Insulin resistance 3/11 137/7206 0.00099197867694 ko04010 MAPK signaling pathway 4/11 321/7206 0.000994187426841 ko05160 Hepatitis C 3/11 153/7206 0.00136642543545 ko05161 Hepatitis B 3/11 173/7206 0.00194690083268 ko05206 MicroRNAs in cancer 3/11 177/7206 0.00207891186263 ko04210 Apoptosis 3/11 180/7206 0.00218153219336 ko04215 Apoptosis - multiple species 2/11 47/7206 0.00220600572258 ko04932 Non-alcoholic fatty liver disease (NAFLD) 3/11 182/7206 0.00225168580458 ko05167 Kaposi's sarcoma-associated herpesvirus infection 3/11 191/7206 0.00258490572535 ko04060 Cytokine-cytokine receptor interaction 3/11 191/7206 0.00258490572535 ko05213 Endometrial cancer 2/11 62/7206 0.00381105234612 ko05223 Non-small cell lung cancer 2/11 66/7206 0.00430857215997 ko05014 Amyotrophic lateral sclerosis (ALS) 2/11 74/7206 0.00538934631348 ko01524 Platinum drug resistance 2/11 76/7206 0.00567718096712 ko05214 Glioma 2/11 79/7206 0.00612201151205 ko05230 Central carbon metabolism in cancer 2/11 81/7206 0.00642722994048 ko05212 Pancreatic cancer 2/11 83/7206 0.006739336873 ko05218 Melanoma 2/11 85/7206 0.0070582953544 ko05210 Colorectal cancer 2/11 86/7206 0.00722033241208 ko05203 Viral carcinogenesis 3/11 277/7206 0.00736900810099 ko04657 IL-17 signaling pathway 2/11 87/7206 0.00738406855637 ko04662 B cell receptor signaling pathway 2/11 88/7206 0.00754949920344 ko05120 Epithelial cell signaling in Helicobacter pylori infection 2/11 92/7206 0.00822807542033 ko04650 Natural killer cell mediated cytotoxicity 2/11 97/7206 0.00911387522882 ko05146 Amoebiasis 2/11 99/7206 0.00947977042577 ko04066 HIF-1 signaling pathway 2/11 123/7206 0.0143720699243 ko04211 Longevity regulating pathway 2/11 123/7206 0.0143720699243 ko01522 Endocrine resistance 2/11 124/7206 0.0145955156759 ko05145 Toxoplasmosis 2/11 126/7206 0.0150469939754 ko05142 Chagas disease (American trypanosomiasis) 2/11 130/7206 0.0159681778674 ko05231 Choline metabolism in cancer 2/11 134/7206 0.0169134375484 ko04380 Osteoclast differentiation 2/11 134/7206 0.0169134375484 ko04933 AGE-RAGE signaling pathway in diabetic complications 2/11 135/7206 0.0171534825044 ko04151 PI3K-Akt signaling pathway 3/11 390/7206 0.0187468328814 ko04725 Cholinergic synapse 2/11 160/7206 0.0236259323509 ko04152 AMPK signaling pathway 2/11 161/7206 0.0239032011772 ko04071 Sphingolipid signaling pathway 2/11 162/7206 0.0241818465086 ko05164 Influenza A 2/11 167/7206 0.0255955802779 ko04068 FoxO signaling pathway 2/11 167/7206 0.0255955802779 ko05418 Fluid shear stress and atherosclerosis 2/11 173/7206 0.027336649755 ko05224 Breast cancer 2/11 174/7206 0.0276315015939 ko05168 Herpes simplex infection 2/11 182/7206 0.0300376798073 ko04150 mTOR signaling pathway 2/11 184/7206 0.030652237813 ko05152 Tuberculosis 2/11 187/7206 0.0315837088845 ko05200 Pathways in cancer 3/11 492/7206 0.0345603593115 ko04072 Phospholipase D signaling pathway 2/11 197/7206 0.0347708603348 ko05010 Alzheimer's disease 2/11 202/7206 0.0364110309467 ko05016 Huntington's disease 2/11 215/7206 0.0408167546166 ko04320 Dorso-ventral axis formation 1/11 31/7206 0.0463482979607 ko04510 Focal adhesion 2/11 240/7206 0.0498379403167