ko pathway ratio_in_study ratio_in_pop p_value ko04668 TNF signaling pathway 23/141 120/7206 4.50645465343e-17 ko04621 NOD-like receptor signaling pathway 23/141 157/7206 2.10521045438e-14 ko04380 Osteoclast differentiation 20/141 134/7206 8.53058954711e-13 ko04064 NF-kappa B signaling pathway 17/141 96/7206 2.85947446424e-12 ko04217 Necroptosis 21/141 178/7206 2.32849559777e-11 ko04210 Apoptosis 21/141 180/7206 2.89051090873e-11 ko05161 Hepatitis B 20/141 173/7206 1.05843987156e-10 ko04620 Toll-like receptor signaling pathway 15/141 100/7206 6.8356544338e-10 ko05160 Hepatitis C 17/141 153/7206 5.50437921545e-09 ko04657 IL-17 signaling pathway 13/141 87/7206 1.04857262715e-08 ko05168 Herpes simplex infection 18/141 182/7206 1.23090932754e-08 ko05152 Tuberculosis 18/141 187/7206 1.89040206871e-08 ko05164 Influenza A 17/141 167/7206 2.09410684015e-08 ko04622 RIG-I-like receptor signaling pathway 11/141 62/7206 2.35749295221e-08 ko05167 Kaposi's sarcoma-associated herpesvirus infection 18/141 191/7206 2.6373151712e-08 ko04623 Cytosolic DNA-sensing pathway 9/141 41/7206 6.69985512675e-08 ko04060 Cytokine-cytokine receptor interaction 17/141 191/7206 1.53663334128e-07 ko05142 Chagas disease (American trypanosomiasis) 14/141 130/7206 1.98268064459e-07 ko05162 Measles 13/141 120/7206 5.17039106629e-07 ko04630 Jak-STAT signaling pathway 13/141 132/7206 1.5559312608e-06 ko05134 Legionellosis 9/141 74/7206 1.22218209347e-05 ko04624 Toll and Imd signaling pathway 7/141 49/7206 4.0893146385e-05 ko04933 AGE-RAGE signaling pathway in diabetic complications 11/141 135/7206 6.13663859085e-05 ko04115 p53 signaling pathway 8/141 74/7206 8.93474768028e-05 ko05140 Leishmaniasis 8/141 75/7206 9.83847771007e-05 ko05145 Toxoplasmosis 10/141 126/7206 0.000166590567659 ko05203 Viral carcinogenesis 15/141 277/7206 0.000316137039798 ko01524 Platinum drug resistance 7/141 76/7206 0.000670748884258 ko05169 Epstein-Barr virus infection 12/141 206/7206 0.000675875029318 ko04660 T cell receptor signaling pathway 9/141 124/7206 0.000686224910463 ko05321 Inflammatory bowel disease (IBD) 6/141 56/7206 0.000732755985238 ko04932 Non-alcoholic fatty liver disease (NAFLD) 11/141 182/7206 0.000837266133175 ko04659 Th17 cell differentiation 8/141 106/7206 0.00105762612938 ko05202 Transcriptional misregulation in cancer 11/141 188/7206 0.00109350570215 ko04722 Neurotrophin signaling pathway 10/141 160/7206 0.00111862387024 ko04931 Insulin resistance 9/141 137/7206 0.0013982931225 ko04917 Prolactin signaling pathway 7/141 87/7206 0.00150007174718 ko05133 Pertussis 7/141 87/7206 0.00150007174718 ko04662 B cell receptor signaling pathway 7/141 88/7206 0.00160354304348 ko04920 Adipocytokine signaling pathway 7/141 89/7206 0.00171249498072 ko05222 Small cell lung cancer 7/141 89/7206 0.00171249498072 ko04215 Apoptosis - multiple species 5/141 47/7206 0.00211691821227 ko04658 Th1 and Th2 cell differentiation 7/141 96/7206 0.00264541029556 ko04214 Apoptosis - fly 6/141 72/7206 0.00273133767371 ko04080 Neuroactive ligand-receptor interaction 1/141 423/7206 0.00323855915584 ko05200 Pathways in cancer 19/141 492/7206 0.00369293998619 ko05131 Shigellosis 6/141 82/7206 0.00522174830536 ko05120 Epithelial cell signaling in Helicobacter pylori infection 6/141 92/7206 0.00907545189935 ko05132 Salmonella infection 6/141 98/7206 0.0121853094709 ko05146 Amoebiasis 6/141 99/7206 0.012768370408 ko05219 Bladder cancer 4/141 48/7206 0.0140433279709 ko05014 Amyotrophic lateral sclerosis (ALS) 5/141 74/7206 0.0146198938106 ko04062 Chemokine signaling pathway 9/141 201/7206 0.0168201876913 ko05418 Fluid shear stress and atherosclerosis 8/141 173/7206 0.0199174322401 ko04930 Type II diabetes mellitus 4/141 54/7206 0.0208710145054 ko05215 Prostate cancer 6/141 111/7206 0.0213595541706 ko05206 MicroRNAs in cancer 8/141 177/7206 0.0225033908661 ko05212 Pancreatic cancer 5/141 83/7206 0.0229422116764 ko04940 Type I diabetes mellitus 3/141 32/7206 0.0240412100536 ko05143 African trypanosomiasis 3/141 32/7206 0.0240412100536 ko05323 Rheumatoid arthritis 5/141 89/7206 0.0299154431619 ko01522 Endocrine resistance 6/141 124/7206 0.0343624078067 ko05221 Acute myeloid leukemia 4/141 63/7206 0.0343971317144 ko04010 MAPK signaling pathway 12/141 321/7206 0.0347415058832 ko04650 Natural killer cell mediated cytotoxicity 5/141 97/7206 0.0411040470162 ko04915 Estrogen signaling pathway 6/141 131/7206 0.0431157754471 ko05332 Graft-versus-host disease 2/141 18/7206 0.0474022551905