ko pathway ratio_in_study ratio_in_pop p_value ko05340 Primary immunodeficiency 12/222 30/7206 2.88406126236e-11 ko05164 Influenza A 24/222 167/7206 2.02679983015e-10 ko04650 Natural killer cell mediated cytotoxicity 18/222 97/7206 6.10702190701e-10 ko04060 Cytokine-cytokine receptor interaction 24/222 191/7206 3.32844007507e-09 ko04612 Antigen processing and presentation 14/222 77/7206 6.92818150068e-08 ko05162 Measles 17/222 120/7206 1.25180612891e-07 ko05168 Herpes simplex infection 21/222 182/7206 1.51214126513e-07 ko04621 NOD-like receptor signaling pathway 19/222 157/7206 2.87478446568e-07 ko05133 Pertussis 14/222 87/7206 3.39376244789e-07 ko04380 Osteoclast differentiation 17/222 134/7206 6.33984234182e-07 ko04217 Necroptosis 19/222 178/7206 2.01838643668e-06 ko05330 Allograft rejection 7/222 24/7206 5.303878791e-06 ko04660 T cell receptor signaling pathway 15/222 124/7206 5.40059789429e-06 ko05150 Staphylococcus aureus infection 8/222 36/7206 1.02746906946e-05 ko05320 Autoimmune thyroid disease 7/222 29/7206 2.09694507015e-05 ko05145 Toxoplasmosis 14/222 126/7206 2.97938716676e-05 ko04658 Th1 and Th2 cell differentiation 12/222 96/7206 3.45128410118e-05 ko04064 NF-kappa B signaling pathway 12/222 96/7206 3.45128410118e-05 ko04062 Chemokine signaling pathway 18/222 201/7206 4.30722564298e-05 ko05152 Tuberculosis 17/222 187/7206 5.84255413618e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 17/222 191/7206 7.62637142281e-05 ko04659 Th17 cell differentiation 12/222 106/7206 9.26856426169e-05 ko04622 RIG-I-like receptor signaling pathway 9/222 62/7206 0.000104087382938 ko04672 Intestinal immune network for IgA production 7/222 37/7206 0.000112119134915 ko05332 Graft-versus-host disease 5/222 18/7206 0.000163697444793 ko04630 Jak-STAT signaling pathway 13/222 132/7206 0.000199211664466 ko03050 Proteasome 8/222 54/7206 0.00021911240147 ko04623 Cytosolic DNA-sensing pathway 7/222 41/7206 0.000220477550659 ko04620 Toll-like receptor signaling pathway 11/222 100/7206 0.000235174505793 ko05161 Hepatitis B 15/222 173/7206 0.000270370881694 ko04662 B cell receptor signaling pathway 10/222 88/7206 0.00034638848647 ko04666 Fc gamma R-mediated phagocytosis 12/222 122/7206 0.000354298414131 ko05160 Hepatitis C 13/222 153/7206 0.000836789817137 ko04210 Apoptosis 14/222 180/7206 0.00127093493464 ko05310 Asthma 4/222 17/7206 0.00152112832704 ko05321 Inflammatory bowel disease (IBD) 7/222 56/7206 0.00153772619363 ko05140 Leishmaniasis 8/222 75/7206 0.0020417576923 ko04940 Type I diabetes mellitus 5/222 32/7206 0.00270737397836 ko04610 Complement and coagulation cascades 8/222 79/7206 0.00284241552925 ko00120 Primary bile acid biosynthesis 4/222 20/7206 0.00287990701335 ko05131 Shigellosis 8/222 82/7206 0.0035893182638 ko05416 Viral myocarditis 6/222 55/7206 0.00657042662084 ko04664 Fc epsilon RI signaling pathway 7/222 77/7206 0.00925841145243 ko05034 Alcoholism 1/222 238/7206 0.0110950254656 ko04145 Phagosome 11/222 162/7206 0.0171605472317 ko00966 Glucosinolate biosynthesis 1/222 1/7206 0.0308076602831 ko05132 Salmonella infection 7/222 98/7206 0.0311043702687 ko04390 Hippo signaling pathway 1/222 188/7206 0.0315051387561 ko05020 Prion diseases 4/222 40/7206 0.0336940209659 ko04611 Platelet activation 10/222 163/7206 0.0344986328864 ko00051 Fructose and mannose metabolism 4/222 42/7206 0.0393657822777 ko00511 Other glycan degradation 3/222 26/7206 0.0445340171724 ko04723 Retrograde endocannabinoid signaling 1/222 175/7206 0.0452806769417 ko05224 Breast cancer 1/222 174/7206 0.0452826629683 ko04310 Wnt signaling pathway 1/222 181/7206 0.0460870412318 ko04728 Dopaminergic synapse 1/222 185/7206 0.0473967187808 ko05144 Malaria 4/222 45/7206 0.0488331684375