ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	34/289	152/7206	6.75349919205e-17
ko04080	Neuroactive ligand-receptor interaction	56/289	423/7206	4.47847525263e-16
ko04727	GABAergic synapse	24/289	110/7206	5.49437882912e-12
ko04728	Dopaminergic synapse	31/289	185/7206	6.66556295983e-12
ko05033	Nicotine addiction	17/289	56/7206	2.68568312581e-11
ko04721	Synaptic vesicle cycle	19/289	80/7206	2.03682254492e-10
ko05032	Morphine addiction	20/289	110/7206	1.0110461117e-08
ko04713	Circadian entrainment	22/289	136/7206	1.72904604369e-08
ko04723	Retrograde endocannabinoid signaling	24/289	175/7206	1.02951643929e-07
ko05030	Cocaine addiction	14/289	73/7206	8.90295915137e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	14/289	74/7206	1.0589836236e-06
ko04726	Serotonergic synapse	19/289	137/7206	1.93980390983e-06
ko04911	Insulin secretion	17/289	117/7206	3.56219450046e-06
ko04725	Cholinergic synapse	19/289	160/7206	1.9492069106e-05
ko04024	cAMP signaling pathway	26/289	279/7206	5.6222572447e-05
ko05031	Amphetamine addiction	13/289	91/7206	6.09895504997e-05
ko04261	Adrenergic signaling in cardiomyocytes	20/289	205/7206	0.000196148394395
ko04514	Cell adhesion molecules (CAMs)	15/289	130/7206	0.000204055384201
ko04730	Long-term depression	11/289	78/7206	0.000252477314728
ko04970	Salivary secretion	12/289	95/7206	0.000381819649838
ko04972	Pancreatic secretion	13/289	111/7206	0.000465650687464
ko04010	MAPK signaling pathway	26/289	321/7206	0.000626529935766
ko04964	Proximal tubule bicarbonate reclamation	6/289	29/7206	0.000859580968082
ko04540	Gap junction	13/289	128/7206	0.00178577321537
ko04961	Endocrine and other factor-regulated calcium reabsorption	8/289	59/7206	0.002269612021
ko04742	Taste transduction	8/289	61/7206	0.00281273351297
ko04966	Collecting duct acid secretion	5/289	26/7206	0.00329318303565
ko04145	Phagosome	15/289	162/7206	0.00329497446079
ko05034	Alcoholism	19/289	238/7206	0.00371618842496
ko04260	Cardiac muscle contraction	10/289	98/7206	0.00569565914232
ko04720	Long-term potentiation	10/289	99/7206	0.0061175888781
ko04060	Cytokine-cytokine receptor interaction	1/289	191/7206	0.0074371972248
ko04360	Axon guidance	18/289	233/7206	0.00943226788399
ko05168	Herpes simplex infection	1/289	182/7206	0.0109020388689
ko04921	Oxytocin signaling pathway	16/289	209/7206	0.0113216032914
ko05110	Vibrio cholerae infection	7/289	63/7206	0.0125551780282
ko05016	Huntington's disease	2/289	215/7206	0.0125880841027
ko05166	HTLV-I infection	4/289	292/7206	0.0140313662006
ko04976	Bile secretion	8/289	80/7206	0.0144103207398
ko04978	Mineral absorption	5/289	40/7206	0.0208923748236
ko04924	Renin secretion	8/289	86/7206	0.0214946274246
ko04621	NOD-like receptor signaling pathway	1/289	157/7206	0.0218000517676
ko04960	Aldosterone-regulated sodium reabsorption	5/289	41/7206	0.0230389532934
ko04973	Carbohydrate digestion and absorption	5/289	42/7206	0.0253233118096
ko04510	Focal adhesion	3/289	240/7206	0.0272465549398
ko05120	Epithelial cell signaling in Helicobacter pylori infection	8/289	92/7206	0.0307509701715
ko04141	Protein processing in endoplasmic reticulum	2/289	184/7206	0.0350187667254
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	7/289	79/7206	0.0384387975979
ko02025	Biofilm formation - Pseudomonas aeruginosa	1/289	1/7206	0.0401054676659
ko04120	Ubiquitin mediated proteolysis	1/289	138/7206	0.0453858406273
ko05418	Fluid shear stress and atherosclerosis	2/289	173/7206	0.048866508679
ko05161	Hepatitis B	2/289	173/7206	0.048866508679
ko04217	Necroptosis	2/289	178/7206	0.0497692989561