ko pathway ratio_in_study ratio_in_pop p_value ko04512 ECM-receptor interaction 22/377 79/7206 4.42865437003e-11 ko04060 Cytokine-cytokine receptor interaction 32/377 191/7206 3.13688378144e-09 ko04510 Focal adhesion 32/377 240/7206 7.86491166957e-07 ko04974 Protein digestion and absorption 18/377 96/7206 1.82624375747e-06 ko00643 Styrene degradation 4/377 4/7206 7.37932610869e-06 ko04672 Intestinal immune network for IgA production 10/377 37/7206 1.33192903236e-05 ko04933 AGE-RAGE signaling pathway in diabetic complications 20/377 135/7206 2.08440132146e-05 ko00350 Tyrosine metabolism 9/377 33/7206 3.35455408308e-05 ko00140 Steroid hormone biosynthesis 10/377 41/7206 3.5517369772e-05 ko05164 Influenza A 22/377 167/7206 5.25931482548e-05 ko04621 NOD-like receptor signaling pathway 20/377 157/7206 0.000183134298865 ko04380 Osteoclast differentiation 18/377 134/7206 0.000195869819263 ko04610 Complement and coagulation cascades 13/377 79/7206 0.000202119626711 ko00120 Primary bile acid biosynthesis 6/377 20/7206 0.000408093502246 ko04064 NF-kappa B signaling pathway 14/377 96/7206 0.000426949513905 ko05150 Staphylococcus aureus infection 8/377 36/7206 0.00043269093619 ko05144 Malaria 9/377 45/7206 0.000441090983207 ko04668 TNF signaling pathway 16/377 120/7206 0.000478833354861 ko05034 Alcoholism 2/377 238/7206 0.000508406300519 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 3/377 4/7206 0.000546346363507 ko05323 Rheumatoid arthritis 13/377 89/7206 0.000669821897453 ko05145 Toxoplasmosis 16/377 126/7206 0.000826291754926 ko04611 Platelet activation 19/377 163/7206 0.000957357144282 ko00281 Geraniol degradation 3/377 5/7206 0.00131281406651 ko00360 Phenylalanine metabolism 5/377 17/7206 0.00139976235974 ko04620 Toll-like receptor signaling pathway 13/377 100/7206 0.00201285709427 ko05321 Inflammatory bowel disease (IBD) 9/377 56/7206 0.00226783105008 ko00254 Aflatoxin biosynthesis 2/377 2/7206 0.00273024079905 ko04724 Glutamatergic synapse 1/377 152/7206 0.00486052581461 ko05146 Amoebiasis 12/377 99/7206 0.00528135380704 ko05162 Measles 14/377 120/7206 0.00532057684243 ko00565 Ether lipid metabolism 7/377 42/7206 0.0055921417404 ko03040 Spliceosome 1/377 145/7206 0.00711093065363 ko04110 Cell cycle 1/377 145/7206 0.00711093065363 ko05160 Hepatitis C 16/377 153/7206 0.00847891879188 ko04630 Jak-STAT signaling pathway 14/377 132/7206 0.00965022371672 ko03013 RNA transport 2/377 166/7206 0.0124048720834 ko00950 Isoquinoline alkaloid biosynthesis 3/377 10/7206 0.0129437382431 ko05161 Hepatitis B 17/377 173/7206 0.0136183408382 ko04622 RIG-I-like receptor signaling pathway 8/377 62/7206 0.0148082874941 ko04670 Leukocyte transendothelial migration 15/377 151/7206 0.0148968081352 ko04658 Th1 and Th2 cell differentiation 11/377 96/7206 0.0167535676321 ko05340 Primary immunodeficiency 5/377 30/7206 0.0184396182686 ko04728 Dopaminergic synapse 3/377 185/7206 0.0186450252952 ko04151 PI3K-Akt signaling pathway 31/377 390/7206 0.0186701732149 ko04960 Aldosterone-regulated sodium reabsorption 6/377 41/7206 0.0187474504422 ko05016 Huntington's disease 4/377 215/7206 0.0189185817656 ko05410 Hypertrophic cardiomyopathy (HCM) 11/377 100/7206 0.0194139706781 ko05416 Viral myocarditis 7/377 55/7206 0.0235785403739 ko05133 Pertussis 10/377 87/7206 0.0239912193995 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/377 5/7206 0.0245691474372 ko04662 B cell receptor signaling pathway 10/377 88/7206 0.0246699080977 ko03320 PPAR signaling pathway 8/377 69/7206 0.0267413200605 ko04022 cGMP-PKG signaling pathway 19/377 216/7206 0.0277976840428 ko00362 Benzoate degradation 2/377 6/7206 0.0355917645455 ko04660 T cell receptor signaling pathway 12/377 124/7206 0.0380057074805 ko05212 Pancreatic cancer 9/377 83/7206 0.0399293837172 ko00040 Pentose and glucuronate interconversions 4/377 26/7206 0.0442771459214 ko05142 Chagas disease (American trypanosomiasis) 12/377 130/7206 0.0461781498735 ko04810 Regulation of actin cytoskeleton 21/377 264/7206 0.0483900932873 ko04640 Hematopoietic cell lineage 7/377 64/7206 0.0485698734135 ko04726 Serotonergic synapse 2/377 137/7206 0.0492335691271 ko04120 Ubiquitin mediated proteolysis 2/377 138/7206 0.0497449188529