ko pathway ratio_in_study ratio_in_pop p_value ko04110 Cell cycle 35/318 145/7206 3.70442870812e-17 ko03440 Homologous recombination 18/318 41/7206 2.01410742243e-14 ko03008 Ribosome biogenesis in eukaryotes 23/318 79/7206 1.5823038357e-13 ko04111 Cell cycle - yeast 24/318 90/7206 3.93959145634e-13 ko03460 Fanconi anemia pathway 16/318 51/7206 2.5075498741e-10 ko03040 Spliceosome 25/318 145/7206 3.24602880311e-09 ko04113 Meiosis - yeast 17/318 70/7206 5.59128324809e-09 ko05322 Systemic lupus erythematosus 25/318 151/7206 7.70401927687e-09 ko03013 RNA transport 24/318 166/7206 2.25060905406e-07 ko03030 DNA replication 10/318 38/7206 3.81498517581e-06 ko04114 Oocyte meiosis 19/318 139/7206 9.81117732669e-06 ko03018 RNA degradation 14/318 84/7206 1.53783586039e-05 ko03022 Basal transcription factors 10/318 44/7206 1.58093887715e-05 ko03410 Base excision repair 9/318 38/7206 2.97317560969e-05 ko05034 Alcoholism 25/318 238/7206 6.23817608076e-05 ko04144 Endocytosis 3/318 342/7206 0.000217673142104 ko03430 Mismatch repair 6/318 22/7206 0.000288358737012 ko04015 Rap1 signaling pathway 2/318 278/7206 0.000501829011239 ko04914 Progesterone-mediated oocyte maturation 13/318 104/7206 0.000612324250332 ko05203 Viral carcinogenesis 25/318 277/7206 0.000789507188596 ko04151 PI3K-Akt signaling pathway 5/318 390/7206 0.000824877285735 ko00240 Pyrimidine metabolism 13/318 110/7206 0.00104642936431 ko04810 Regulation of actin cytoskeleton 2/318 264/7206 0.00107219139105 ko04022 cGMP-PKG signaling pathway 1/318 216/7206 0.00109272962697 ko04921 Oxytocin signaling pathway 1/318 209/7206 0.00163063454797 ko04062 Chemokine signaling pathway 1/318 201/7206 0.00241226552396 ko05010 Alzheimer's disease 1/318 202/7206 0.00245016713345 ko04360 Axon guidance 2/318 233/7206 0.0030768737751 ko05166 HTLV-I infection 24/318 292/7206 0.00313452987293 ko05152 Tuberculosis 1/318 187/7206 0.0033656542606 ko03450 Non-homologous end-joining 4/318 15/7206 0.00345010881544 ko03420 Nucleotide excision repair 7/318 46/7206 0.00370258991199 ko04115 p53 signaling pathway 9/318 74/7206 0.00499607345566 ko04010 MAPK signaling pathway 5/318 321/7206 0.00759437607703 ko03020 RNA polymerase 5/318 29/7206 0.00803982079245 ko04722 Neurotrophin signaling pathway 1/318 160/7206 0.0103247114552 ko04725 Cholinergic synapse 1/318 160/7206 0.0103247114552 ko04071 Sphingolipid signaling pathway 1/318 162/7206 0.0104355054699 ko04014 Ras signaling pathway 4/318 279/7206 0.0104559883745 ko04072 Phospholipase D signaling pathway 2/318 197/7206 0.0126010549274 ko04218 Cellular senescence 15/318 177/7206 0.0142014167156 ko05167 Kaposi's sarcoma-associated herpesvirus infection 2/318 191/7206 0.0182181232777 ko04913 Ovarian steroidogenesis 7/318 63/7206 0.0202694532119 ko04371 Apelin signaling pathway 2/318 177/7206 0.0248845485059 ko04932 Non-alcoholic fatty liver disease (NAFLD) 2/318 182/7206 0.0256796087167 ko04915 Estrogen signaling pathway 1/318 131/7206 0.0310261065929 ko04630 Jak-STAT signaling pathway 1/318 132/7206 0.0310540375157 ko04380 Osteoclast differentiation 1/318 134/7206 0.0312855007609 ko04933 AGE-RAGE signaling pathway in diabetic complications 1/318 135/7206 0.0314888777172 ko04726 Serotonergic synapse 1/318 137/7206 0.0320707533937 ko05205 Proteoglycans in cancer 5/318 271/7206 0.0336159388726 ko05418 Fluid shear stress and atherosclerosis 2/318 173/7206 0.0360766063481 ko04666 Fc gamma R-mediated phagocytosis 1/318 122/7206 0.0446089229348 ko04660 T cell receptor signaling pathway 1/318 124/7206 0.0448005247798 ko00190 Oxidative phosphorylation 1/318 127/7206 0.0456841299602 ko01200 Carbon metabolism 1/318 128/7206 0.0461366304592 ko04530 Tight junction 4/318 228/7206 0.0475409021165