ko pathway ratio_in_study ratio_in_pop p_value ko04137 Mitophagy - animal 22/611 82/7206 7.12702395412e-07 ko04060 Cytokine-cytokine receptor interaction 37/611 191/7206 1.90742869564e-06 ko04710 Circadian rhythm 14/611 43/7206 6.60557176537e-06 ko04650 Natural killer cell mediated cytotoxicity 21/611 97/7206 4.68642888292e-05 ko04380 Osteoclast differentiation 26/611 134/7206 5.24596594585e-05 ko04610 Complement and coagulation cascades 18/611 79/7206 8.00909347024e-05 ko03010 Ribosome 1/611 129/7206 0.000306873839559 ko03040 Spliceosome 2/611 145/7206 0.000430118236137 ko05340 Primary immunodeficiency 9/611 30/7206 0.000601220703893 ko05321 Inflammatory bowel disease (IBD) 13/611 56/7206 0.000639131081389 ko05034 Alcoholism 7/611 238/7206 0.000803929739535 ko00120 Primary bile acid biosynthesis 7/611 20/7206 0.000884862876945 ko04922 Glucagon signaling pathway 22/611 128/7206 0.00114992977241 ko04022 cGMP-PKG signaling pathway 32/611 216/7206 0.00171251638224 ko04659 Th17 cell differentiation 19/611 106/7206 0.00216174781009 ko04020 Calcium signaling pathway 37/611 265/7206 0.0022351013188 ko04110 Cell cycle 3/611 145/7206 0.00226910932609 ko03013 RNA transport 4/611 166/7206 0.00263977522071 ko05152 Tuberculosis 28/611 187/7206 0.00302427458142 ko04672 Intestinal immune network for IgA production 9/611 37/7206 0.00305711804767 ko00592 alpha-Linolenic acid metabolism 6/611 19/7206 0.00376638395168 ko04068 FoxO signaling pathway 25/611 167/7206 0.00453723568572 ko04660 T cell receptor signaling pathway 20/611 124/7206 0.00488204514262 ko04371 Apelin signaling pathway 26/611 177/7206 0.00566196521767 ko04072 Phospholipase D signaling pathway 28/611 197/7206 0.00603729701528 ko00051 Fructose and mannose metabolism 9/611 42/7206 0.00748796741299 ko05203 Viral carcinogenesis 12/611 277/7206 0.0082024472748 ko04138 Autophagy - yeast 14/611 81/7206 0.0083053557833 ko04658 Th1 and Th2 cell differentiation 16/611 96/7206 0.00832991778084 ko04070 Phosphatidylinositol signaling system 18/611 112/7206 0.0088939423366 ko05150 Staphylococcus aureus infection 8/611 36/7206 0.00915519919722 ko04630 Jak-STAT signaling pathway 20/611 132/7206 0.0104689928215 ko05224 Breast cancer 6/611 174/7206 0.0124768368756 ko04136 Autophagy - other 7/611 31/7206 0.0132424959458 ko05322 Systemic lupus erythematosus 5/611 151/7206 0.017353052361 ko04621 NOD-like receptor signaling pathway 22/611 157/7206 0.0191448126837 ko04711 Circadian rhythm - fly 4/611 13/7206 0.0196940161909 ko04146 Peroxisome 14/611 89/7206 0.0203072905851 ko05323 Rheumatoid arthritis 14/611 89/7206 0.0203072905851 ko04640 Hematopoietic cell lineage 11/611 64/7206 0.0209640844411 ko04930 Type II diabetes mellitus 10/611 54/7206 0.0222456618558 ko03015 mRNA surveillance pathway 2/611 93/7206 0.0228557759933 ko05145 Toxoplasmosis 18/611 126/7206 0.023668667799 ko05230 Central carbon metabolism in cancer 13/611 81/7206 0.0242474312246 ko04270 Vascular smooth muscle contraction 21/611 154/7206 0.0272386880933 ko04113 Meiosis - yeast 1/611 70/7206 0.0285829079666 ko04921 Oxytocin signaling pathway 27/611 209/7206 0.0309030208182 ko04611 Platelet activation 22/611 163/7206 0.0311940696623 ko05140 Leishmaniasis 12/611 75/7206 0.0330420438837 ko04745 Phototransduction - fly 7/611 38/7206 0.0380555645584 ko00590 Arachidonic acid metabolism 9/611 52/7206 0.0388622848485 ko00950 Isoquinoline alkaloid biosynthesis 3/611 10/7206 0.0463688671963 ko04066 HIF-1 signaling pathway 17/611 123/7206 0.0473903883982 ko05167 Kaposi's sarcoma-associated herpesvirus infection 24/611 191/7206 0.04742455485 ko04925 Aldosterone synthesis and secretion 15/611 105/7206 0.0489301656621